Nitrosopumilus adriaticus: NADRNF5_0861
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Entry
NADRNF5_0861 CDS
T03758
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nin
Nitrosopumilus adriaticus
Pathway
nin00290
Valine, leucine and isoleucine biosynthesis
nin00620
Pyruvate metabolism
nin01100
Metabolic pathways
nin01110
Biosynthesis of secondary metabolites
nin01210
2-Oxocarboxylic acid metabolism
nin01230
Biosynthesis of amino acids
Module
nin_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nin00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NADRNF5_0861 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NADRNF5_0861 (leuA)
Enzymes [BR:
nin01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NADRNF5_0861 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
DUF4147
Glyco_hydro_97
Motif
Other DBs
NCBI-ProteinID:
AJW70555
UniProt:
A0A0D5C2J8
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All DBs
Position
712433..713947
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AA seq
504 aa
AA seq
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MNVRIFDTTLRDGEQTIGVSLSPDQKLAIAKKLDELGVDAIEAGFPVISEGELKAVKMIT
SEGLSCEIAGLTRTIKKDIDAAIDAGLNYIHTFIATSDIHLEHKLKMTRDQALEKAIEAV
EYGKSRGLQVEFSAEDASRTEREFLKKVFGEVAKAGADRVNIPDTVGYSTPEYMAEITRD
TVEVTKLPVSVHCHNDFGLAVANSLAGIHAGASCAHVTINGIGERAGNASLEELSMALKC
LPYDQKYETNIKSELIYETSRFISKTVGIIVQPNKAIVGANAFGHESGIHTHGVLSNPLT
YEPISPELVGRKRWLQVGKHAGVHGMNAMLAEYGVKPTDEQSKQILEKVKVLGDQGKQIT
DVELLSIASDVLGEKDLKRIVQLSGFSVSTGIGTMPYAFVKLNIDGQDHIGTDYGVGPVD
AALNAIQKITGKISEIRIKDYGLASISGGSSALCEVTVKVEDALGNKVSAKSVGEDIVTT
SVKAVIDAINRIMLKKMLQEKQVN
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
ttgaacgttagaatatttgataccactttaagagatggagagcaaacaattggtgtatca
ttatcgccagatcaaaaattagcaatagcaaaaaaacttgatgaattaggcgttgatgca
attgaagctggctttccagttatttcagaaggagaattaaaagcagttaagatgataact
agtgaaggattatcttgtgagattgcaggattaacaaggaccataaaaaaagatattgac
gctgcaattgatgctggattaaattacattcataccttcattgcaacatctgacattcac
ttggagcataaactcaaaatgacaagagatcaagcccttgaaaaagcaattgaagctgta
gagtatggtaaatcacgtggtcttcaagtagagttttcagctgaagatgcttcaagaaca
gaaagagagtttttaaaaaaagtgtttggtgaagtggcaaaggcaggagctgatagagtt
aacattcctgacactgtaggatattctactcctgaatacatggcagaaattactagagat
acagtagaggtcacaaaacttccagtaagtgttcattgtcataatgattttggactagct
gttgcaaactcattagctggaattcatgcaggagcatcatgtgctcatgtaacaattaat
ggaattggtgaacgtgcaggaaatgcatccctagaagaactttctatggcattgaaatgt
ttgccatatgatcaaaaatatgaaaccaatatcaaatctgaattaatttacgaaacatcg
agatttatctcaaagactgttggaatcatagttcagccaaacaaagcaattgttggcgct
aatgcatttggtcatgaatcaggcattcacacacatggtgttttgagtaatcctctaacc
tacgagcctataagccctgaattagttggacgaaaaagatggcttcaagttggaaaacat
gcaggagttcatggaatgaatgcaatgcttgcagaatatggcgttaaaccaactgatgag
caatcaaaacaaatcctagagaaagtcaaagtgttaggtgaccaaggaaaacaaatcact
gatgtggagttactttcgattgcaagtgatgttttgggagaaaaggatctcaaaagaatt
gttcaattaagtggattctcagtatcaacaggtattggaacgatgccttatgcatttgta
aaattaaacattgatggtcaggatcatataggaactgattatggggtgggcccagtagat
gctgccctaaacgctatccaaaagattactggaaagatttcggagattagaatcaaagat
tatggattagcttctatttctggtggttcctctgcgttatgtgaagtaacagtaaaggtt
gaagatgctcttgggaataaagtatctgcaaaatcagtcggtgaggatattgttactact
tctgtaaaggcagtaattgatgcaatcaatcgaatcatgctcaaaaagatgcttcaagaa
aagcaagtcaactaa
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