Candidatus Nitrosopumilus sediminis: NSED_06260
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Entry
NSED_06260 CDS
T02303
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nir
Candidatus Nitrosopumilus sediminis
Pathway
nir00290
Valine, leucine and isoleucine biosynthesis
nir00620
Pyruvate metabolism
nir01100
Metabolic pathways
nir01110
Biosynthesis of secondary metabolites
nir01210
2-Oxocarboxylic acid metabolism
nir01230
Biosynthesis of amino acids
Module
nir_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NSED_06260
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NSED_06260
Enzymes [BR:
nir01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NSED_06260
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
DUF4147
Glyco_hydro_97
Motif
Other DBs
NCBI-ProteinID:
AFS83054
UniProt:
K0BC52
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All DBs
Position
complement(1037294..1038808)
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AA seq
504 aa
AA seq
DB search
MKIRIFDTTLRDGEQTIGVSLSPDQKLSIAKKLDELGVDAIEAGFPVISEGELKAVKMIT
SEGLSCEIAGLTRTIKKDIDAAVDAGLNYIHTFIATSDIHLEHKLKMTRDQALEKAIEAV
EYGKSRGLQVEFSAEDASRTDREFLKKVFGEVAKAGADRVNIPDTVGYSTPEYMAKITKD
TVEATKLPVSVHCHNDFGLAVANSLAGIHAGAACAHVTINGIGERAGNASLEELSMALKC
LPYDQKYETNIKSELIYDASRFISKTVGIIVQPNKAIVGANAFGHESGIHTHGVLSNPLT
YEPISPELVGRKRWLQVGKHAGVHGMNAMLSEYGVKPTEEQSQQILDKVKVLGDQGKQIT
DVELLSIASDVLGEKDLKKIVQLTGFSVSTGIGTMPYAFVKLNIDGQDHVGTDYGVGPVD
AALNAIQKITGKLSEIRIKDYGLASISGGSSALCEVTVKVEDALGNKVSAKSVGEDIVTT
SVKAVIDAINHIMLKKLLHEKQVR
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgaaaattagaatatttgatacaacattaagagatggggaacaaacaattggtgtttct
ttatctccagatcaaaaattatccattgccaaaaaactcgatgaacttggtgttgatgca
attgaagctggttttccagtaatctctgaaggtgagttaaaagcagtaaaaatgattact
agtgaaggattgtcatgtgaaattgcaggattaacaagaactattaaaaaagacattgat
gctgcagttgacgctggattaaactacatccacacattcattgcaacttctgatattcat
ttagaacataaactcaaaatgactcgagatcaagctcttgagaaagcaattgaagcagta
gagtatggaaaatctcgtggattgcaagttgaattttcagctgaagatgcttctagaact
gatagagaatttttaaaaaaagtatttggcgaggttgcaaaagccggagcagaccgtgta
aacattcctgatactgtggggtactctactcctgaatacatggcaaaaatcactaaagat
acagtagaagctacaaaacttccagtaagtgttcattgtcataatgattttggattggca
gttgcaaattctttggcaggaattcatgcaggagctgcatgtgcacatgttacaataaat
ggaattggtgaacgagctggtaatgcttcattagaagaactttctatggcattgaagtgt
ttaccatatgatcaaaaatatgagacgaacatcaaatctgaattaatttacgatgcctca
agatttatctctaaaactgtgggtattattgttcagcctaacaaggccatagttggagca
aacgcatttggccatgaatcaggaattcatacacatggtgtattgagtaatccgctaaca
tacgagccgattagcccggaattagtaggacgaaaaagatggcttcaagttggaaaacat
gcaggggttcatggtatgaatgcaatgctttctgaatatggagtaaaacctactgaagaa
caatcccagcaaatcttagacaaagtcaaagtgttaggtgaccaaggaaaacagatcact
gatgtggagttgctctctattgcaagtgacgtcttgggagaaaaagacctcaaaaaaatt
gttcaactaactggattctcagtatccactggaattggaactatgccttatgcatttgta
aaactaaacattgatggtcaggaccatgtcggaactgattatggggtaggacctgtggat
gcagcactaaatgcaattcaaaaaattactggaaagctttctgaaatcagaattaaggat
tatggattagcatcaatttctggcggttctagtgcattatgtgaggttacagtaaaggtt
gaagatgcattaggaaacaaagtctctgcaaaatctgttggtgaagacattgtaactaca
tcagttaaagcagtaattgatgccattaatcatatcatgctcaaaaaattgttacatgaa
aaacaggtacgataa
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