Neisseria lactamica: NLA_15420
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Entry
NLA_15420 CDS
T01368
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
nla
Neisseria lactamica
Pathway
nla00790
Folate biosynthesis
nla01100
Metabolic pathways
nla01240
Biosynthesis of cofactors
Module
nla_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
nla00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NLA_15420 (folC)
Enzymes [BR:
nla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NLA_15420 (folC)
6.3.2.17 tetrahydrofolate synthase
NLA_15420 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CBN87752
UniProt:
E4ZEG6
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Position
1660641..1661915
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AA seq
424 aa
AA seq
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MKTLQDWLSHLETAHSGGLIDMGLERVGEVKKRMKLEPQCPVVVVAGTNGKGSVCAYLTQ
IYKQAGYKTGTLTSPHLLRYNERIAVNAEPVSDDTITASFERIEAAHGEISLTYFEFNTL
AAVDIFMREQVDVMILEVGLGGRLDAVNVFDGDCAVVTSVDLDHQAFLGDTVEQVGFEKA
GVFRSGKPAICGQNPAPESLVAHAEAIGAKLLMVQRDFEFHAMENIQWNYRFHPQHSDDR
ARNRNALPFPALRGAYQLSNAACALTVLECLNGKLPADIGAIKRGLLLVENPGRFQVLPG
RPLTVLDVGHNPHAARALRRSLMNLAFAQKRTAVFSMLSDKDIDGVLEIVKDQFDEWYIA
PLDVPRGMTLESLQDKLHEHGIENIQTFAAVREAYRAAASKAGENDRIVVFGSFHTVADV
MSVL
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacactgcaagactggctctcgcatttggaaaccgcccacagcggcggcttgatc
gatatgggcttggaacgcgtaggcgaagtgaaaaaacggatgaagctcgagccgcaatgc
cccgtcgtcgtcgtcgcgggaacaaacggcaaaggctcggtctgcgcctatctgacacag
atttacaaacaggcgggctacaaaaccggcacattaaccagcccccatttattgcgttac
aacgaacgtatcgccgtcaacgccgagccggtttcagacgacacaatcaccgcttccttc
gaacgcattgaagcagcgcacggcgaaatatcgctgacttattttgaattcaacacttta
gccgcagtggatatttttatgcgcgaacaagtcgatgtgatgatattggaagtcggcttg
ggcggacgcttggacgcggttaatgtgttcgacggcgattgcgcggtggttaccagcgtg
gatttggaccatcaggcgtttttgggcgatacggtcgaacaggtcggttttgaaaaagca
ggcgtgttccgcagcggcaaacccgccatctgcggtcaaaaccccgcgcccgaatcattg
gtcgcacacgccgaagccataggcgcgaaactgctgatggtacagcgcgatttcgagttt
cacgcgatggaaaacatccaatggaactaccgcttccatccgcagcattcagacgaccgg
gcgcgcaaccgcaatgccctgcccttccccgcattgcgcggcgcataccagctttccaac
gccgcctgcgcgctgaccgtgttggaatgcttgaacggcaaactgccggcggacatcggc
gccatcaagcgcggtttgttgctggttgaaaaccccggacgcttccaagtcctgcccggc
cgtccgctgaccgttttggatgtcggacacaatccccacgccgcccgcgccctgcgacgc
agcctgatgaatctggcgtttgcgcaaaaacgcaccgccgtgttcagtatgctgtccgac
aaagacatagacggcgtgttggaaattgtcaaagaccagtttgacgaatggtatatcgca
cctttggacgtgccgcgcggaatgacgctcgagagcctgcaagacaaactgcacgaacac
ggcatcgaaaacatacagacattcgccgccgtccgcgaagcctaccgggcggcagcctca
aaagcgggcgaaaacgacagaatcgtcgtattcggctcatttcataccgttgccgacgtg
atgtcggtactgtaa
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