Neisseria lactamica: NLA_19380
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Entry
NLA_19380 CDS
T01368
Symbol
purL
Name
(GenBank) phophoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
nla
Neisseria lactamica
Pathway
nla00230
Purine metabolism
nla01100
Metabolic pathways
nla01110
Biosynthesis of secondary metabolites
Module
nla_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nla00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NLA_19380 (purL)
Enzymes [BR:
nla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NLA_19380 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CBN88139
UniProt:
E4ZA67
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Position
2078209..2082165
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AA seq
1318 aa
AA seq
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MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFVGSEKALDAATVEKLQAL
LAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWLEG
ALTDEQKQQWAALLHDRMTESVLPDFQTASKLFHHLESETFSTVDVLGGGKEALVKANTE
TGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSL
FGMIRDTHNAHLEGTVVAYKDNSSVIEGAKIERFYPDAAENQGYRFHEEDTHIIMKVETH
NHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPGLKQPWEQDYGKP
EHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSI
QAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMNTGTNDASLDFNSVQRGNPEIERR
AQEVIDRCWQLGDKNPIISIHDVGAGGLSNAFPELVNDAGRGAVFELREVPLEEHGLTPL
QIWCNESQERYVLSILEKDLDAFRAICERERCPFAVVGTATGDGHLKVRDDLFSNNPVDL
PLNVLLGKPPKTTRTDKTVAPSEKPFNAGDIDITEAAYRVLRLPAVAAKNFLITIGDRSV
GGMTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPAAALFNAPASGRMCVGEAI
TNIAAANIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSM
KTVWQDGEEKKSVVSPLSLIISAFAPVQDVRKTVTPELKNVEDSVLLFIDLGFGKARMGG
SAFGQVYNNMSGDAPDLDDTSRLKAFYNVIQQLIAEDKLLAYHDRSDGGLFATLAEMAFA
GRCGISADIDCLMDKFLPIHYPDFQGDPAEDLSDELYNHAAIKILFNEELGAVIQIRQQD
RDYVDAAFEAAGLTGAVSRIGSPDFDNESISFFGYGYFLEQNRADLQRAWQETSHAIQKL
RDNPACADSEFAMIGDNGRSTLFADVKFDVNEDIAAPFINSGAKPKIAILREQGVNGQIE
MAAAFTRAGFDAYDVHMSDLMAGRFRLADFKMLAACGGFSYGDVLGAGEGWAKSILFHPA
LRDQFAAFFADPNTLTLGVCNGCQMVSNLAEIIPGTAGWPKFKRNLSEQFEARLSMVHVP
KSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQYVDGQNQVTQTYPLNP
NGSPQGIAGVTNADGRVTIMMPHPERVYRAAQMSWKPENWTELSGWYRLFAGARKALG
NT seq
3957 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtcgttttgcccttgcgcggcgttaccgccctttccgatttccgtgttgaaaaa
ctcttgcaaaaagccgccgcactcggtctgcccgaagtcaaattaagcagcgaattttgg
tatttcgtcggcagcgagaaagcacttgatgccgcgactgtcgaaaaactgcaggcctta
ctggcagcgcaaagcgttgaacaaacgccaaaagcgcgcgagggcttgcatttgtttttg
gtcacaccccgtttgggtacgatttcgccgtgggcttccaaggcgaccaatatcgcggaa
aactgcggtttggcaggcatcgaacgcatcgagcgcggtatggcggtgtggctggaaggt
gcgcttaccgatgaacagaaacagcaatgggcggctttgctgcacgaccgcatgactgaa
tccgtgctgcccgattttcagacggcatccaaattattccaccatctcgaatccgaaacc
ttttccaccgtcgatgttttgggcggcggtaaagaggctttggtcaaagccaataccgaa
acgggtttggcactctccgccgacgaaatcgattatctggttgaaaactatcaggctttg
cagcgcaatccgtccgatgtggaactgatgatgttcgcacaggcaaacagcgaacactgc
cgccacaaaatcttcaacgccgacttcatcctcaacggcgaaaaacagccgaaatccctc
ttcggtatgatacgcgacacgcacaacgcgcatctcgaaggcacggtcgtcgcttataaa
gacaattcgtccgtaatcgaaggcgcgaaaatcgagcgtttctatccggatgcggcggaa
aaccaaggctaccgtttccacgaggaagacacgcatatcatcatgaaagtggaaacgcac
aaccatccgaccgccattgcgccgtttgcgggagcggcgacgggcgcgggcggcgaaatc
cgcgacgaaggtgcgacgggcaaaggttcgcgtccgaaagcaggcctgaccggctttacc
gtgtccaacctcaacatccccggcctcaaacagccgtgggaacaagactacggcaagccg
gaacatatttcctcgccgctggacattatgattgaaggccccatcggcggcgcggcgttt
aacaacgaattcggccgccccaacctcttgggctacttccgcacttttgaagaaaaattc
gacggtcaggttcgcggctaccacaaaccgattatgattgcgggcggcttgggcagcatt
caggcgcagcaaacacataaagacgaaatccccgaaggcgcgttgctgatccaactgggc
ggcccgggcatgcttatcggcttgggcggcggtgcggcttcttcgatgaataccggtaca
aatgacgcgtctttggacttcaactccgtgcaacgcggcaaccccgaaatcgaacgccgt
gcgcaggaagtcatcgaccgctgctggcagctcggcgacaaaaacccgattatctccatc
cacgacgtgggcgcgggcggtctgtccaacgccttccccgaactcgtcaacgatgccgga
cgcggcgcggtattcgagctgcgcgaagtgccgttggaagaacacggtttaacgcctttg
caaatctggtgcaacgaatcgcaagagcgttatgtgttgtcgattttggaaaaagatttg
gatgccttccgcgccatctgcgaacgcgaacgctgcccgtttgccgtggtcggcacggcg
accggcgacggtcatttgaaagtgcgcgacgatttgttctccaacaaccctgtcgatttg
ccgctgaacgtcttgctcggcaaaccgcccaaaaccacgcgtaccgacaaaacggttgcg
ccgtctgaaaaaccgtttaacgcgggcgatatcgacattaccgaagccgcctaccgcgtt
ttgcgcctgcctgccgtagccgccaaaaacttcttgattaccatcggcgaccgcagcgtc
ggcggcatgacccaccgcgaccaaatggtcggcaaataccaaaccccggtagccgactgc
gccgtgactatgatgggcttcaacacctatcgcggcgaagcgatgtctatgggcgaaaaa
ccggccgccgccctgtttaacgcgcctgcctcgggcagaatgtgcgtcggcgaagccatc
accaacatcgcggcagccaacatcggcgacatcggcaacatcaaactctccgccaactgg
atggcggcgtgcggcaacgagggcgaagacgaaaaactctaccgtaccgtcgaagcggtt
tctaaagcctgtcaggcattggatttgagcatccccgtgggcaaagacagcctgtcgatg
aaaaccgtttggcaggatggcgaagagaaaaaatccgtcgtttcgcctttaagcctgatt
atttctgcgttcgcgccggttcaagacgtgcgcaaaaccgttacgcccgaattgaaaaac
gtcgaagacagcgtattgctgtttatcgatttgggcttcggcaaagcgcgtatgggcggc
tcggcgtttggtcaggtgtacaacaatatgagcggcgacgcgcccgatttggacgataca
agtcgtctgaaagcgttttacaacgtgattcagcagcttatcgccgaagacaaactcttg
gcgtatcacgaccgcagcgacggcggcttgtttgcgacgctggcggaaatggcgtttgcg
gggcggtgcggtatcagtgccgatatagattgcctgatggataaattcctgccgattcat
tatccggatttccaaggcgacccggccgaagacttatctgacgaactttataatcatgcc
gccattaaaatcttatttaatgaagaattaggtgcggttatccaaatccgccaacaagat
agggattatgttgatgcggcatttgaagcggccggcttaaccggtgcggtcagccggatt
ggctctcctgattttgacaatgaatctatttctttctttggttacggttatttcctagaa
caaaaccgtgccgacctgcaacgcgcatggcaggaaacttctcacgccattcaaaaactg
cgcgacaaccccgcctgcgccgacagcgagtttgccatgattggcgacaacggacgcagc
acattgtttgccgacgtgaaatttgatgtaaacgaagacatcgccgcgccgtttatcaac
agcggcgcgaaacccaaaatcgccatcctgcgcgaacagggcgtgaacgggcaaatcgaa
atggccgccgccttcacacgcgccggattcgatgcctacgacgtgcatatgtccgacctg
atggcaggccgcttccgccttgccgacttcaaaatgctggcggcgtgcggcggcttcagc
tacggcgacgtactcggcgcgggcgaaggctgggcgaaatccatcctgttccaccccgcc
ttacgcgaccaatttgccgccttctttgccgatccgaacacgctgacattgggcgtgtgc
aacggctgccaaatggtcagcaacctcgccgaaatcatccccggcacggcaggctggccg
aagttcaaacgcaacttgagcgaacagtttgaagcgcgcctgagtatggttcatgttcca
aaatccgcatcgctgattctgaacgaaatgcaaggctccagcctgcctgtcgtggtcagc
cacggcgaaggacgcgccgacttcgcgcttcacggcggcaatatttccgctgatttgggc
attgcgctgcaatatgtagacggacaaaaccaggttacccaaacctacccgctcaaccct
aacggctcaccacaaggtatcgccggtgtaaccaacgccgacggccgcgtgaccatcatg
atgccgcatccggaacgcgtgtaccgcgccgcgcaaatgagctggaaaccggaaaactgg
acggaactctccggctggtaccgcctctttgccggtgcaagaaaagccttgggctaa
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