Neisseria lactamica: NLA_4660
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Entry
NLA_4660 CDS
T01368
Symbol
murF
Name
(GenBank) UDP-MurNAc-pentapeptide synthetase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nla
Neisseria lactamica
Pathway
nla00300
Lysine biosynthesis
nla00550
Peptidoglycan biosynthesis
nla01100
Metabolic pathways
nla01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nla00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NLA_4660 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NLA_4660 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NLA_4660 (murF)
Enzymes [BR:
nla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NLA_4660 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CBN86706
UniProt:
E4ZBH9
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Position
444839..446197
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AA seq
452 aa
AA seq
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MKPLDLNFICQALKLPMPSENKPVSRIVTDSRDIRAGDVFFALAGGRFDAHDFVEDVLAA
GAAAVVVSREDCASLKDALKVDDTLAALQTLAKAWRENVNPFVFGITGSVGKTTVKEMLA
AVLRRRFGNDAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALANNAMRAHIGCGFDGVGDIAKAKSEIYQGLCSDGIALIPQEDANLAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGNERAAVVLPVPGRHNVHNAAAAAALALAAG
LGLNDVAEGLKGFSNIKGRLNVKSGIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAETFGADGLWFAAKDPLIQ
VLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccactggatctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
aacaaacccgtgtcgcgcatcgtcaccgacagccgcgacatccgcgcgggcgatgtgttt
ttcgcattggcgggcgggcggtttgacgcgcatgattttgttgaagacgtattggctgcg
ggtgcggcggcggttgtggtttcgcgcgaagattgcgcgtctttgaaagacgcgttgaaa
gtcgatgacacgcttgccgcattgcaaacgctggcaaaggcgtggcgtgaaaatgtgaat
ccgtttgtgttcggtattaccggttcggtcggcaagacgacggtaaaggaaatgctggct
gcggtattgcgccgccgtttcggcaatgatgctgtgttggcgacggcgggcaatttcaac
aaccacatcggattgccgcttactttgttgaaattaaacgaaaaacaccgctatgccgtg
attgaaatgggcatgaaccattttggcgaactggcggttttaacgcaaatcgccaaaccc
gatgccgccttggccaacaatgccatgcgcgcccatatcggctgcggttttgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatcaaggcttatgttcagacggcattgcg
ctgattcctcaagaagatgccaatctggctgttttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgtccacgcggaaaatatcgtgctgaaacct
ttgtcgtgcgaatttgatttggtgtgcggaaacgaacgcgcagccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctggctttggctgcgggt
ttgggtttgaacgatgtggcggaaggtttgaaaggtttcagcaacatcaaaggccgtctg
aacgtcaaatccggcatcaagggcgcgaccctgattgatgatacctacaatgcgaatccc
gacagtatgaaagccgcgattgacgtgttggcgcgtatgcctgcgccgcgtattttcgtg
atgggcgatatgggcgaactgggcgaggacgaagcagccgccatgcacgccgaagtcggc
gcgtatgcccgcgaccaaggcatcgaagcggcttattttgtcggcgacaacagcgtcgaa
gcggcggaaacatttggcgcggacggtttgtggttcgccgccaaagacccgttgattcaa
gtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga
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