Neisseria lactamica: NLA_9550
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Entry
NLA_9550 CDS
T01368
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nla
Neisseria lactamica
Pathway
nla00290
Valine, leucine and isoleucine biosynthesis
nla00620
Pyruvate metabolism
nla01100
Metabolic pathways
nla01110
Biosynthesis of secondary metabolites
nla01210
2-Oxocarboxylic acid metabolism
nla01230
Biosynthesis of amino acids
Module
nla_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NLA_9550 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NLA_9550 (leuA)
Enzymes [BR:
nla01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NLA_9550 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
CBN87182
UniProt:
E4ZCU9
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All DBs
Position
1005393..1006946
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AA seq
517 aa
AA seq
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MTQTNRVIIFDTTLRDGEQSPGAAMTKEEKIRVARQLEKLGVDIIEAGFAAASPGDFDSV
NAIAKIITKSTVCSLARAVENDVRKAGEAVSPAPKKRIHTFIATSPIHMEHKLKMKPQQV
VDAAVKAVKIAKEYTDDVEFSAEDAVRSDLDFLAKIFTAVIEAGATTINIPDTVGYSIPS
VWYERISNIIKSVPNGDKVVWSTHCHNDLGMAVANSLAAVQAGARQVECTVNGLGERAGN
ASLEEIVMALKVRHDLFGLETGIDTTQIVPSSKLVSTITGYPVQPNKAIVGANAFSHESG
IHQDGVLKHRETYEIMSAESVGWATNRLSLGKLSGRNAFKTKLADLGIELESEEALNAAF
ARFKELADKKREIFDEDLHALVSDEMGNMNAESYKFISQKISTETGEEPRADIVFSIKGE
EKRASATGSGPVDAIFKAIESVAQSGAALQIYSVNAVTQGTESQGETSVRLARGNRVVNG
QGADTDVLVATAKAYLSALSKLEFSAAKPKAQGSGTI
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgacacagaccaaccgcgtaattatttttgatactaccctgcgcgacggcgaacaatcg
cccggcgccgctatgaccaaagaggaaaaaatccgcgtcgcccgccaattggaaaaattg
ggcgtggacatcatcgaagcgggttttgccgctgccagcccgggcgatttcgattcggtc
aatgcgattgccaaaatcatcaccaaatccacagtctgctcgttggcgcgtgccgttgaa
aacgatgtgcgtaaggcaggcgaagccgtttcgcctgcgccgaaaaaacgcatccatacc
ttcatcgccaccagccccatccatatggagcacaaactgaaaatgaagccgcagcaggtc
gtcgatgcggcggtcaaagcagtgaaaatcgccaaagaatacaccgacgatgtggaattt
tccgccgaagacgccgtgcgttcggatttggacttcctcgccaaaatctttacggcggtt
atcgaagcgggtgcgaccaccatcaatattcccgataccgtcggctattccattccttct
gtgtggtacgaacgtatcagcaacatcatcaaaagcgtgcccaacggcgacaaagtagtc
tggtcgacccactgccacaacgatttgggtatggcggttgccaattcgctggccgctgtt
caggcaggcgcgcgccaggtggaatgtaccgtcaacggtttgggcgaacgcgcgggcaat
gccagccttgaagaaatcgtgatggcgttgaaagtgcgccacgacttgttcggtttggaa
accggcatcgacaccacgcaaatcgtgccttcgtccaaactggtgtccaccattaccggc
tatcccgtccagcccaacaaagccatcgtcggcgcgaatgcgttttcgcacgaatcgggc
atccatcaggacggcgtgctgaaacaccgagaaacttatgagattatgtccgccgaatcg
gtcggttgggcaacaaatcgtttgagcttgggcaaattgtccggccgcaacgccttcaaa
accaagctggcggatttgggcatcgagttggaaagcgaagaagcgttgaacgccgcgttt
gcccgcttcaaagaactcgccgacaaaaaacgcgaaatcttcgatgaagacctgcacgcg
ctggtgtcggacgaaatgggcaatatgaatgccgaaagctacaaattcatctcccaaaaa
atcagcaccgaaaccggcgaagagccgcgcgccgacatcgtgttcagcatcaagggtgaa
gaaaaacgcgcttccgccacaggctccggccccgtggatgcgattttcaaagcgattgaa
agcgtggcgcaaagcggcgcggctttgcagatttattccgtcaacgccgtcacgcaaggt
acggaaagccagggcgaaaccagcgtccgtctggcgcgcggcaaccgcgtcgtcaacggt
cagggcgcggataccgacgttttggtcgccaccgccaaagcctacctttccgccttgagc
aaactggaatttagtgccgccaaaccgaaggcgcagggcagcggtacgatttga
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