Nomascus leucogenys (northern white-cheeked gibbon): 100579676
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Entry
100579676 CDS
T03265
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X1
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00010
Glycolysis / Gluconeogenesis
nle00620
Pyruvate metabolism
nle01100
Metabolic pathways
nle01200
Carbon metabolism
nle01230
Biosynthesis of amino acids
nle04910
Insulin signaling pathway
nle04930
Type II diabetes mellitus
nle04932
Non-alcoholic fatty liver disease
nle04950
Maturity onset diabetes of the young
Module
nle_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
nle_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100579676 (PKLR)
00620 Pyruvate metabolism
100579676 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100579676 (PKLR)
04950 Maturity onset diabetes of the young
100579676 (PKLR)
04932 Non-alcoholic fatty liver disease
100579676 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
nle04147
]
100579676 (PKLR)
Enzymes [BR:
nle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
100579676 (PKLR)
Exosome [BR:
nle04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100579676 (PKLR)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK
PK_C
IMPDH
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
100579676
NCBI-ProteinID:
XP_030680175
Ensembl:
ENSNLEG00000012082
LinkDB
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Position
12:45909900..45922063
Genome browser
AA seq
604 aa
AA seq
DB search
MSIQENISSLQLWSWVSKSQRDLAKSILIGAPGAQLGFMPLTTQQCGADPQRGRPREVCS
GMEGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSI
IATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANIRKAVESFAASPLSYRP
VAIALDTKGPEIRTGIPQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRV
VPVGGHIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVR
DLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVS
DGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSD
VANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRD
PTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCR
GVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRV
LSIS
NT seq
1815 nt
NT seq
+upstream
nt +downstream
nt
atgtcgatccaggagaacatatcatccctgcagctttggtcatgggtctctaagtcccaa
agagacttagcaaagtccatcctgattggggctccaggagcccagctgggcttcatgcct
ctgacaacccaacagtgtggagcagacccacagagagggagacccagagaggtgtgcagt
ggcatggaagggccagcagggtatctgcggcgggccagtgtggcccaactgacccaggag
ctgggcactgccttcttccagcagcagcagctgccagctgctatggcagacaccttcctg
gaacacctctgcctactggacatcgactcggagcccgtggctgctcgcagtaccagcatc
attgccaccatcgggccggcatctcgctcggtggagcgcctcaaggagatgatcaaggcc
gggatgaacattgcgcgactcaacttctcccatggctcccacgagtaccacgctgagtcc
atcgccaacatccggaaggcggtggagagctttgcagcttccccgctcagttaccggccc
gtggccatcgccctggacaccaagggaccggagatccgcactgggatcccgcaggggggt
ccagagtcggaagtggagctggtgaagggctcccaggtgctggtgactgtggaccccgcg
ttccggacgcgggggaacgcgaacaccgtgtgggtggactaccccaatattgtccgggtc
gtgccggtggggggccacatctacattgacgacgggctcatctccctagtggtccagaaa
atcggcccagagggactggtgacccaagtggagaacggcggcgtcctgggcagccggaag
ggcgtgaacttgccaggggcccaggtggacttgcccgggctgtccgagcaggacgtccga
gacctgcgcttcggggtggagcatggcgtggacatcgtctttgcctcctttgtgcggaaa
gccagcgacgtggctgccgtcagggctgctctgggtccggaaggacacggcatcaagatc
atcagcaaaattgagaaccacgaaggcgtgaagaggtttgatgaaatcctggaggtgagc
gacggcatcatggtggcacggggggacctaggcatcgagatcccagcagagaaggttttc
ctggctcagaagatgatgattgggcgctgcaacttggcgggcaagcctgttgtctgtgct
acacagatgctggagagcatgattaccaagccccggccaacgagggcagagacaagtgat
gtggccaacgctgtgctggatggggctgactgcatcatgctgtcaggggagactgccaag
ggcaacttccctgtggaagccgtgaagatgcagcatgcgatcgcccgggaggcagaggcc
gcagtgtatcaccggcagctgtttgaggagctacgtcgggcagcgccactaagccgtgat
cccactgaggtcaccgccattggcgcagtggaggctgccttcaagtgctgtgctgctgcc
atcattgtgctgaccacaactggccgctcagcccagcttctgtctcggtaccgacctcgg
gcagcagtcattgctgtcacccgctctgcccaggctgcccgccaggtccacttatgccga
ggagtcttccccttgctttaccgtgaacctccagaagccatctgggcagatgatgtagat
cgccgggtgcaatttggcattgaaagtggaaagctccgtggcttcctccgtgttggagac
ctggtgattgtggtgacaggctggcgacctggctccggctacaccaacatcatgcgggtg
ctgagcatatcctga
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