Nomascus leucogenys (northern white-cheeked gibbon): 100583180
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Entry
100583180 CDS
T03265
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00280
Valine, leucine and isoleucine degradation
nle00640
Propanoate metabolism
nle00785
Lipoic acid metabolism
nle01100
Metabolic pathways
nle01210
2-Oxocarboxylic acid metabolism
Module
nle_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
100583180 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100583180 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100583180 (BCKDHA)
Enzymes [BR:
nle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
100583180 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100583180
NCBI-ProteinID:
XP_030651600
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Position
17:84446970..84477168
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AA seq
445 aa
AA seq
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MAVAIVAARVWRPNRGLSQAALLLLRRPGARGLARSHPHRQQQQFSSLDDKPQFPGASAE
FIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILY
ESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYG
NISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGA
ASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDG
NDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHP
ISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPTQL
RKQQESLARHLQTYGEHYPLEHFDK
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
atggcggtagcgattgttgcagcgagggtctggcggccaaaccgtggcctgagccaggct
gccctcctgctgctgcggcggcctggggctcgaggactggctagatctcacccccacagg
cagcagcagcagttctcatctctggatgacaagccccagttcccaggggcctcggcagag
tttatagacaagttggaattcatccagcccaacgtcatctctggaatccccatctaccgc
gtcatggaccggcaaggccagatcatcaaccccagcgaggacccccacctgccgaaggag
aaggtgctgaagctctataagagcatgacactgcttaacaccatggaccgcatcctctat
gagtctcagcggcagggccggatctccttctacatgaccaactatggtgaggagggcacg
cacgtggggagtgctgccgccctggacaacacggacctggtgtttggccagtaccgggag
gcaggtgtgctgatgtatcgggactaccccctggaactattcatggcccagtgctatggc
aacatcagtgacttgggcaaggggcgccagatgcccgtccactacggctgcaaggaacgc
cacttcgtcactatctcctctccactggccacgcagatccctcaggcggtgggggcggcc
tacgcagccaagcgggccaacgccaacagggtggtcatctgttactttggcgagggggcg
gccagcgaaggggacgcccatgccggcttcaacttcgctgccacacttgagtgccccatc
atcttcttctgccggaacaatggctacgccatctccacgcccacctccgagcagtatcgc
ggcgatggcattgcagcacgaggccctgggtatggcatcatgtcaatccgcgtggatggt
aatgatgtgtttgctgtgtacaatgccacaaaggaggcccgacgccgggctgtggcagag
aaccagcccttcctcatcgaggccatgacctacaggattgggcaccacagcaccagtgac
gacagttcagcgtaccgctcagtggacgaggtcaattactgggacaagcaggaccacccc
atctcccggctgcggcactacctgctgagccaaggctggtgggatgaggagcaggagaag
gcctggaggaagcagtcccgcaagaaggtgatggaggcctttgagcaggctgagcggaag
cccaaacccaaccccaacctgctcttctcagacgtttatcaagagatgcccacccagctc
cgcaagcagcaggagtccctggcccgccacctgcagacctacggggagcactaccccctg
gagcacttcgataagtga
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