| Entry |
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| Symbol |
PPP3CA
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| Name |
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
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| KO |
| K04348 | serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] |
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| Organism |
nle Nomascus leucogenys (northern white-cheeked gibbon)
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| Pathway |
| nle04625 | C-type lectin receptor signaling pathway |
| nle04650 | Natural killer cell mediated cytotoxicity |
| nle04658 | Th1 and Th2 cell differentiation |
| nle04660 | T cell receptor signaling pathway |
| nle04662 | B cell receptor signaling pathway |
| nle05022 | Pathways of neurodegeneration - multiple diseases |
| nle05163 | Human cytomegalovirus infection |
| nle05166 | Human T-cell leukemia virus 1 infection |
| nle05167 | Kaposi sarcoma-associated herpesvirus infection |
| nle05170 | Human immunodeficiency virus 1 infection |
| nle05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
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| Brite |
KEGG Orthology (KO) [BR:nle00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100583664 (PPP3CA)
04310 Wnt signaling pathway
100583664 (PPP3CA)
04370 VEGF signaling pathway
100583664 (PPP3CA)
04020 Calcium signaling pathway
100583664 (PPP3CA)
04022 cGMP-PKG signaling pathway
100583664 (PPP3CA)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
100583664 (PPP3CA)
04218 Cellular senescence
100583664 (PPP3CA)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100583664 (PPP3CA)
04650 Natural killer cell mediated cytotoxicity
100583664 (PPP3CA)
04660 T cell receptor signaling pathway
100583664 (PPP3CA)
04658 Th1 and Th2 cell differentiation
100583664 (PPP3CA)
04659 Th17 cell differentiation
100583664 (PPP3CA)
04662 B cell receptor signaling pathway
100583664 (PPP3CA)
09152 Endocrine system
04922 Glucagon signaling pathway
100583664 (PPP3CA)
04921 Oxytocin signaling pathway
100583664 (PPP3CA)
04924 Renin secretion
100583664 (PPP3CA)
09156 Nervous system
04724 Glutamatergic synapse
100583664 (PPP3CA)
04728 Dopaminergic synapse
100583664 (PPP3CA)
04720 Long-term potentiation
100583664 (PPP3CA)
09158 Development and regeneration
04360 Axon guidance
100583664 (PPP3CA)
04380 Osteoclast differentiation
100583664 (PPP3CA)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100583664 (PPP3CA)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100583664 (PPP3CA)
05170 Human immunodeficiency virus 1 infection
100583664 (PPP3CA)
05163 Human cytomegalovirus infection
100583664 (PPP3CA)
05167 Kaposi sarcoma-associated herpesvirus infection
100583664 (PPP3CA)
09171 Infectious disease: bacterial
05152 Tuberculosis
100583664 (PPP3CA)
09164 Neurodegenerative disease
05010 Alzheimer disease
100583664 (PPP3CA)
05014 Amyotrophic lateral sclerosis
100583664 (PPP3CA)
05020 Prion disease
100583664 (PPP3CA)
05022 Pathways of neurodegeneration - multiple diseases
100583664 (PPP3CA)
09165 Substance dependence
05031 Amphetamine addiction
100583664 (PPP3CA)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100583664 (PPP3CA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:nle01009]
100583664 (PPP3CA)
Enzymes [BR:nle01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
100583664 (PPP3CA)
Protein phosphatases and associated proteins [BR:nle01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Catalytic subunits
100583664 (PPP3CA)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
9:complement(83401809..83732285)
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| AA seq |
521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ |
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| NT seq |
1566 nt +upstreamnt +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaggcacatcttatgaaggagggaaggctggaagagagtgtt
gcattgagaataataacagagggtgcatcaattcttcgacaggaaaaaaatttgctggat
attgatgcgccagtcacagtttgtggggacattcatggacaattctttgacttgatgaag
ctctttgaagtcgggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaggaatgtaaaataaagtattcagaacgcgtatatgacgcctgtatggat
gcctttgactgccttcccctggctgccctgatgaaccaacagtttctgtgtgtacatggt
ggtttgtctccagagattaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcgtatggacctatgtgtgatatcctgtggtcagaccccctggaagattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcgtacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatacttcgagcc
cacgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgtttttacttggtcccttccatttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactagggtcagaa
gaagatggatttgatggtgcaacagctgcagcccggaaagaagtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcttgaccccaactggcatgctccccagcggagtactttctggaggg
aagcaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaagccaagggcttagaccgaattaat
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcacctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga |
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