Nomascus leucogenys (northern white-cheeked gibbon): 100585363
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Entry
100585363 CDS
T03265
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00230
Purine metabolism
nle00670
One carbon pool by folate
nle01100
Metabolic pathways
nle01523
Antifolate resistance
Module
nle_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100585363 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100585363 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100585363 (GART)
Enzymes [BR:
nle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
100585363 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
100585363 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
100585363 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_4
Dala_Dala_lig_C
ATP-grasp_3
Sacchrp_dh_NADP
RimK
LUD_dom
Motif
Other DBs
NCBI-GeneID:
100585363
NCBI-ProteinID:
XP_003263923
Ensembl:
ENSNLEG00000003903
UniProt:
G1QV60
LinkDB
All DBs
Position
25:complement(18901733..18942518)
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISVSDHTALAQ
FCKEEKIEFVVVGPEAPLAAGIVGNLMSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVIEELLDGEEVSCLCFTDGRAVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGMLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAINFEGAIYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNILVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDDVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPKVFSWLQQEG
HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRDDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttataattggcagtggaggaagggaacatacgctggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaacgcaggcactgcc
tgctctgaaaagatttcaaataccgccatctcagtcagtgaccacactgcccttgctcaa
ttctgcaaagaggagaaaattgaatttgtagttgttggaccagaagcacctctggctgct
gggattgttgggaacctgatgtctgcaggagtgcgatgctttggcccaacagcagaagcg
gctcagttagagtccagcaaaaggtttgccaaagagtttatggacagacatggaatccca
actgcacaatggaaggctttcaccaaacctgaagaggcctgcagcttcattttgagtgca
gacttccctgctttggtggtgaaggccagtggtcttgcagctggaaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaagagatcatgcaggagaaagccttt
ggggcagctggagaaacaattgttattgaagaacttcttgacggagaagaggtgtcttgt
ctgtgtttcactgatggcagggctgtggcccccatgcccccagcacaggaccataagcga
ttactggagggagatggcggccctaacacagggggaatgggagcctattgtccagcccct
caggtttctaatgatctattactaaaaattaaagatactgttcttcagaggacagtggat
ggcatgcagcaagagggtactccatatacaggtattctctatgctggaataatgctgacc
aaggatggcccaaaagttctagagtttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtccaccttagatggaatg
ctctgcacatctctgcctgtttggctagaaaaccacaccgccctaactgttgtcatggca
agcaaaggttatcctggagactacaccaagggtgtagagataacagggtttcctgaggct
caagctctaggactggaggtgttccatgcaggcactgccctcaaaaatggcaaagtagta
actcatgggggtagagttcttgcagtcacagccatccgggaaaatctcatatcagccctc
gaggaagccaagaaaggactagctgctataaactttgagggagcaatttataggaaagac
atcggctttcgtgccatagctttcctccagcagcccaggggtttgacttacaaggaatct
ggagtagacattgcagctggaaatattctggtcaagaaaattcagcctttagcaaaagcc
acttccagatcaggctgtaaagttgatcttggaggttttgctggtctttttgatttaaaa
gcagctggtttcaaagatccccttctggcatctggaacagatggcgttggaactaaacta
aagattgcccagctgtgcaataaacatgataccattggtcaagatttggtagcaatgtgt
gttaatgatattctggcacaaggagcagagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcagtgtaactgaagctgttgttgctggaattgccaaagcttgtgga
aaagctggatgtgctctccttggaggtgaaacagcagaaatgcctgacatgtatccacct
ggagagtatgacctagctgggtttgccgttggtgccatggagcgagatcagaaactccct
cacctagaaagaatcactgagggtgatgatgttgttggaatagcttcatctggtcttcat
agcaatggatttagccttgtgaggaaaatcgtggcaaaatcttccctccagtactcctct
ccagcgcctgatggttgtggtgaccagactttaggggacttacttctcacgcctaccaga
atctacagccattcactgttacccgtcctacgttcaggacatgtcaaagcctttgcccat
attactggtggaggattactagagaacatccccagagtcctccctgagaaacttggggta
gatttagatgcccagacctggaggatccccaaggtcttctcatggttacagcaggaagga
cacctctctgaggaagagatggccagaacatttaactgtggggttggcgctgtccttgtg
gtatcaaaggagcagacagagcagattctgagggatatccagcagcacaaggaagaagcc
tgggtgattggcagtgtggttgcacgagccgaaggttcgccacgtgtgaaagtcaagaat
ctgattgaaagcatgcaaataaatgggtcagtgttgaagaatggctccctgacaaatcat
ttctcttttgaaaaaaaaaaggccagagtggctgtcttaatatctggaacaggatcgaac
ctgcaagcactcatagacagtactcgggaaccaaatagttctgcacaaatcgatattgtt
atctccaacaaagccgcagtagctgggttagataaagcggaaagagctggtattcccact
agagtaattaatcataaattgtataaaaatcgtgtagaatttgacagtgcaattgaccta
gtccttgaagagttctccatagacatagtctgtcttgcaggattcatgagaattctttct
ggcccctttgtccgaaagtggaatggaaaaatgctcaatatccacccatccttgctccct
tcttttaagggttcgaatgcccatgagcaagccctggaaaccggagtcacagttactggg
tgcactgtacactttgtagctgaagatgtagacgctgggcaaattattttgcaagaagct
gttcccgtgaagagggatgatactgtcgcaactctttctgaaagagtaaaactagcagaa
cataaaatatttcctgcagcccttcagctggtggccagtggaactgtacagcttggagaa
aatggcaagatctgttgggttaaagaggaatga
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