KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100586279
Entry
100586279         CDS       T03265                                 
Symbol
GSTM4
Name
(RefSeq) glutathione S-transferase Mu 4 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00480  Glutathione metabolism
nle00980  Metabolism of xenobiotics by cytochrome P450
nle00982  Drug metabolism - cytochrome P450
nle00983  Drug metabolism - other enzymes
nle01100  Metabolic pathways
nle01524  Platinum drug resistance
nle05200  Pathways in cancer
nle05204  Chemical carcinogenesis - DNA adducts
nle05207  Chemical carcinogenesis - receptor activation
nle05208  Chemical carcinogenesis - reactive oxygen species
nle05225  Hepatocellular carcinoma
nle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100586279 (GSTM4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100586279 (GSTM4)
   00982 Drug metabolism - cytochrome P450
    100586279 (GSTM4)
   00983 Drug metabolism - other enzymes
    100586279 (GSTM4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100586279 (GSTM4)
   05204 Chemical carcinogenesis - DNA adducts
    100586279 (GSTM4)
   05207 Chemical carcinogenesis - receptor activation
    100586279 (GSTM4)
   05208 Chemical carcinogenesis - reactive oxygen species
    100586279 (GSTM4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100586279 (GSTM4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100586279 (GSTM4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100586279 (GSTM4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:nle02000]
    100586279 (GSTM4)
Enzymes [BR:nle01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100586279 (GSTM4)
Transporters [BR:nle02000]
 Other transporters
  Pores ion channels [TC:1]
   100586279 (GSTM4)
SSDB
Motif
Pfam: GST_N GST_C GST_C_3 GST_C_6 GST_N_3 GST_N_2 GST_C_2 GST_C_7 Bromo_TP
Other DBs
NCBI-GeneID: 100586279
NCBI-ProteinID: XP_003267962
Ensembl: ENSNLEG00000003159
UniProt: G1QSD7
LinkDB
Position
12:complement(66253015..66276240)
AA seq 218 aa
MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
EKLKPEYLEGLPTMVQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPKCLDAFPN
LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
NT seq 657 nt   +upstreamnt  +downstreamnt
atgtccatgacactggggtactgggacatccgcgggctggcccatgccatccgcctgctc
ctggaatacacagactcaagctacgaggaaaagaagtacacgatgggggacgctcctgac
tatgacagaagccagtggctgaatgaaaaattcaagctgggcctggactttcccaatctg
ccctacttgattgatggggctcacaagatcacccagagcaacgccatcctgcgctacatt
gcccgcaagcacaatctgtgtggggagacagaagaggagaagattcgtgtggacattttg
gagaaccaggctatggacgtctccaatcagctggccagagtctgctacagccctgacttt
gagaaactgaagccagaatacttggagggacttcctacaatggtgcagcacttctcacag
ttcctggggaagaggccatggtttgttggagacaagatcacctttgtagatttccttgcc
tatgatgtccttgacctccaccgtatatttgagcccaagtgcttggacgcctttccaaat
ctgaaggacttcatctcccgctttgagggcttggagaagatctctgcctacatgaagtcc
agccgcttcctcccaaaacctctgtacacaagggtggctgtctggggcaacaagtaa

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