Nomascus leucogenys (northern white-cheeked gibbon): 100587596
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Entry
100587596 CDS
T03265
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00240
Pyrimidine metabolism
nle00670
One carbon pool by folate
nle01100
Metabolic pathways
nle01232
Nucleotide metabolism
nle01523
Antifolate resistance
nle04981
Folate transport and metabolism
Module
nle_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
100587596 (TYMS)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100587596 (TYMS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100587596 (TYMS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100587596 (TYMS)
Enzymes [BR:
nle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
100587596 (TYMS)
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Gene cluster
GFIT
Motif
Pfam:
Thymidylat_synt
Motif
Other DBs
NCBI-GeneID:
100587596
NCBI-ProteinID:
XP_030666540
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All DBs
Position
4:59544527..59556225
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AA seq
313 aa
AA seq
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MPVAGSELPRRPLPSAAQERDAEPRPPHGELQYLGQIEHILRCGVRKDDRTGTGTLSVFG
MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS
LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC
AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI
TGLKPGDFIHTLGDAHVYLNHIEPLKIQLQREPRPFPKLKILRKVEKIDDFKAEDFQIEG
YNPHPTIKMEMAV
NT seq
942 nt
NT seq
+upstream
nt +downstream
nt
atgcccgtcgccggctccgagctgccgcgccggcccttgccgtccgccgcacaggagcgg
gacgctgagccgcgtccgccgcacggggagctgcagtacctggggcagatcgagcacatt
ctccgctgcggcgtcaggaaggacgaccgcacgggcaccggcaccctgtcggtattcggc
atgcaggcgcgctatagcctgagagatgaatttcctctgctgacaaccaaacgtgtgttc
tggaagggtgttttggaggagttgctgtggtttatcaagggatccacaaatgctaaagag
ctgtcttccaagggagtgaaaatctgggatgccaatggatcccgagactttttggacagc
ctgggattctccaccagagaagaaggggacttgggcccagtttatggcttccagtggagg
cattttggggcagaatacagagatatggaatcagattattcaggacagggagttgaccaa
ctgcaaagagtgattgacaccatcaaaaccaaccctgacgacagaagaatcatcatgtgc
gcttggaatccaagagatcttcctctgatggcgctgcctccatgccatgccctctgccag
ttctatgtggtgaacagtgagctgtcctgccagctgtaccagagatcgggagacatgggc
ctaggtgtgcctttcaacatcgccagctacgccctgctcacgtacatgattgcacacatc
acgggcctgaagccaggtgactttatacacactttgggagatgcacatgtttacctgaat
cacatcgagccactgaaaattcagcttcagcgagaacccagacctttcccaaagctcaag
attcttcgaaaagttgagaaaattgatgacttcaaagctgaagactttcagattgaaggg
tacaatccacatccaactattaaaatggaaatggctgtttag
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