KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100587718
Entry
100587718         CDS       T03265                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04012  ErbB signaling pathway
nle04620  Toll-like receptor signaling pathway
nle04664  Fc epsilon RI signaling pathway
nle04668  TNF signaling pathway
nle04912  GnRH signaling pathway
nle04926  Relaxin signaling pathway
nle04935  Growth hormone synthesis, secretion and action
nle04936  Alcoholic liver disease
nle05132  Salmonella infection
nle05135  Yersinia infection
nle05142  Chagas disease
nle05161  Hepatitis B
nle05166  Human T-cell leukemia virus 1 infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05169  Epstein-Barr virus infection
nle05208  Chemical carcinogenesis - reactive oxygen species
nle05417  Lipid and atherosclerosis
nle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100587718 (MAP2K4)
   04012 ErbB signaling pathway
    100587718 (MAP2K4)
   04668 TNF signaling pathway
    100587718 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100587718 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    100587718 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100587718 (MAP2K4)
   04926 Relaxin signaling pathway
    100587718 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    100587718 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    100587718 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100587718 (MAP2K4)
   05161 Hepatitis B
    100587718 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100587718 (MAP2K4)
   05169 Epstein-Barr virus infection
    100587718 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100587718 (MAP2K4)
   05135 Yersinia infection
    100587718 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100587718 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100587718 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    100587718 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100587718 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nle01001]
    100587718 (MAP2K4)
Enzymes [BR:nle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100587718 (MAP2K4)
Protein kinases [BR:nle01001]
 Serine/threonine kinases: STE group
  STE7 family
   100587718 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 100587718
NCBI-ProteinID: XP_003262638
Ensembl: ENSNLEG00000014536
UniProt: G1RWT9
LinkDB
Position
19:complement(65784989..65909246)
AA seq 399 aa
MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFT
LNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMV
HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL
MSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRS
GNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL
ATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKE
LLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1200 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcagcggcacc
ccgggcccagtagggtccccggcgccgggccacccggccgtcagcagcatgcagggtaaa
cgcaaagcactgaagttgaattttgcaaatccacctttcaaatctacagcaaggtttact
ctgaatcccaatcctaccggagttcagaacccacacatagagagactgagaacacacagc
attgagtcatcaggaaaactgaagatctcccctgaacaacactgggatttcactgcagag
gacttgaaagaccttggagaaattggacgaggagcttatggttctgtcaacaaaatggtc
cacaaaccaagtgggcaaataatggcagttaaaagaattcggtcaacagtggatgaaaaa
gaacaaaaacaacttcttatggatttggatgtagtaatgcggagtagtgattgcccatac
attgttcagttttatggtgcactcttcagagagggtgactgttggatctgtatggaactc
atgtctacctcgtttgataagttttacaaatatgtatatagtgtattagatgatgttatt
ccagaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccacttaaaa
gaaaacttgaaaataattcacagagatatcaaaccttccaatattcttctggacagaagt
ggaaatattaagctctgtgacttcggcatcagtggacagcttgtggactctattgccaag
acaagagatgctggctgtaggccatacatggcacctgaaagaatagacccaagtgcatca
cgacaaggatatgatgtccgctctgatgtctggagtttggggatcacattgtatgagttg
gccacgggccgatttccttatccaaagtggaatagtgtatttgatcaactaacacaagtc
gtgaaaggagatcctccgcagctgagtaattctgaggaaagggaattctccccgagtttc
atcaactttgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtataaagag
cttctgaaacatccctttattttgatgtatgaagaacgtgctgttgaggtcgcatgctat
gtttgtaaaatcctggatcaaatgccagctactcccagctctcccatgtatgtcgattga

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