Entry |
|
Symbol |
EIF2S1
|
Name |
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
|
KO |
K03237 | translation initiation factor 2 subunit 1 |
|
Organism |
nle Nomascus leucogenys (northern white-cheeked gibbon)
|
Pathway |
nle04141 | Protein processing in endoplasmic reticulum |
nle04932 | Non-alcoholic fatty liver disease |
nle05022 | Pathways of neurodegeneration - multiple diseases |
nle05168 | Herpes simplex virus 1 infection |
|
Brite |
KEGG Orthology (KO) [BR:nle00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100587728 (EIF2S1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100587728 (EIF2S1)
04137 Mitophagy - animal
100587728 (EIF2S1)
09143 Cell growth and death
04210 Apoptosis
100587728 (EIF2S1)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
100587728 (EIF2S1)
05164 Influenza A
100587728 (EIF2S1)
05162 Measles
100587728 (EIF2S1)
05168 Herpes simplex virus 1 infection
100587728 (EIF2S1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100587728 (EIF2S1)
05012 Parkinson disease
100587728 (EIF2S1)
05014 Amyotrophic lateral sclerosis
100587728 (EIF2S1)
05020 Prion disease
100587728 (EIF2S1)
05022 Pathways of neurodegeneration - multiple diseases
100587728 (EIF2S1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100587728 (EIF2S1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100587728 (EIF2S1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03012 Translation factors [BR:nle03012]
100587728 (EIF2S1)
04131 Membrane trafficking [BR:nle04131]
100587728 (EIF2S1)
Translation factors [BR:nle03012]
Eukaryotic type
Initiation factors
eIF-2
100587728 (EIF2S1)
Membrane trafficking [BR:nle04131]
Autophagy
ER-phagy
ER stress-related proteins
100587728 (EIF2S1)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Position |
1a:84352361..84380265
|
AA seq |
315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTT
TLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEV
DGDDDAEEMEAKAED |
NT seq |
948 nt +upstreamnt +downstreamnt
atgccgggtctaagttgtagattttatcaacacaaatttcctgaggtggaagatgtagtg
atggtgaatgtcagatccattgctgaaatgggggcttatgtcagcttgctggaatacaac
aacattgaaggcatgattcttcttagtgaattatccagaaggcgtatccgttctatcaac
aaactcatccgaattggcaggaatgagtgtgtggttgtcattagggtggacaaagaaaaa
ggatatattgatttgtcaaaaagaagagtttctccagaggaagcaatcaaatgtgaagac
aaattcacaaaatccaaaactgtttatagcattcttcgtcatgttgctgaggtgttagaa
tacaccaaggatgagcagctggaaagcctattccagaggactgcctgggtctttgatgac
aagtacaagagacctggatatggtgcctatgatgcatttaagcatgcagtctcagaccca
tctattttggatagtttagatttgaatgaagatgaacgggaagtactcattaataatatt
aataggcgcttgaccccacaggctgtcaaaattcgagcagatattgaagtggcttgttat
ggttatgaaggcattgatgctgtaaaagaagccctaagagcaggtttgaattgttctaca
gaaaacatgcccattaagattaatctaatagctcctcctcggtatgtaatgactacgaca
accctggagagaacagaaggcctttctgtcctcagtcaagctatggctgttatcaaagaa
aagattgaggaaaagaggggtgtgttcaatgttcaaatggagcccaaagtggtcacagat
acagatgagactgaacttgcgaggcagatggagaggcttgaaagagaaaatgccgaagtg
gatggagatgatgatgcagaagaaatggaagccaaagctgaagattaa |