KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100588160
Entry
100588160         CDS       T03265                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04022  cGMP-PKG signaling pathway
nle04137  Mitophagy - animal
nle04141  Protein processing in endoplasmic reticulum
nle04151  PI3K-Akt signaling pathway
nle04210  Apoptosis
nle04211  Longevity regulating pathway
nle04261  Adrenergic signaling in cardiomyocytes
nle04668  TNF signaling pathway
nle04720  Long-term potentiation
nle04722  Neurotrophin signaling pathway
nle04725  Cholinergic synapse
nle04728  Dopaminergic synapse
nle04911  Insulin secretion
nle04912  GnRH signaling pathway
nle04915  Estrogen signaling pathway
nle04918  Thyroid hormone synthesis
nle04922  Glucagon signaling pathway
nle04925  Aldosterone synthesis and secretion
nle04926  Relaxin signaling pathway
nle04927  Cortisol synthesis and secretion
nle04928  Parathyroid hormone synthesis, secretion and action
nle04932  Non-alcoholic fatty liver disease
nle04934  Cushing syndrome
nle04935  Growth hormone synthesis, secretion and action
nle05010  Alzheimer disease
nle05012  Parkinson disease
nle05014  Amyotrophic lateral sclerosis
nle05020  Prion disease
nle05022  Pathways of neurodegeneration - multiple diseases
nle05030  Cocaine addiction
nle05031  Amphetamine addiction
nle05034  Alcoholism
nle05161  Hepatitis B
nle05163  Human cytomegalovirus infection
nle05166  Human T-cell leukemia virus 1 infection
nle05203  Viral carcinogenesis
nle05207  Chemical carcinogenesis - receptor activation
nle05215  Prostate cancer
nle05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100588160 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100588160 (ATF4)
   04668 TNF signaling pathway
    100588160 (ATF4)
   04022 cGMP-PKG signaling pathway
    100588160 (ATF4)
   04151 PI3K-Akt signaling pathway
    100588160 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100588160 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    100588160 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100588160 (ATF4)
   04922 Glucagon signaling pathway
    100588160 (ATF4)
   04912 GnRH signaling pathway
    100588160 (ATF4)
   04915 Estrogen signaling pathway
    100588160 (ATF4)
   04926 Relaxin signaling pathway
    100588160 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    100588160 (ATF4)
   04918 Thyroid hormone synthesis
    100588160 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    100588160 (ATF4)
   04925 Aldosterone synthesis and secretion
    100588160 (ATF4)
   04927 Cortisol synthesis and secretion
    100588160 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100588160 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    100588160 (ATF4)
   04728 Dopaminergic synapse
    100588160 (ATF4)
   04720 Long-term potentiation
    100588160 (ATF4)
   04722 Neurotrophin signaling pathway
    100588160 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    100588160 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100588160 (ATF4)
   05203 Viral carcinogenesis
    100588160 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    100588160 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100588160 (ATF4)
   05161 Hepatitis B
    100588160 (ATF4)
   05163 Human cytomegalovirus infection
    100588160 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100588160 (ATF4)
   05012 Parkinson disease
    100588160 (ATF4)
   05014 Amyotrophic lateral sclerosis
    100588160 (ATF4)
   05020 Prion disease
    100588160 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    100588160 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    100588160 (ATF4)
   05031 Amphetamine addiction
    100588160 (ATF4)
   05034 Alcoholism
    100588160 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100588160 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100588160 (ATF4)
   04934 Cushing syndrome
    100588160 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:nle03000]
    100588160 (ATF4)
Transcription factors [BR:nle03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    100588160 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF3450 DUF4407 Nop53 DUF4192 AAA_13 bZIP_Maf Laminin_II
Other DBs
NCBI-GeneID: 100588160
NCBI-ProteinID: XP_003264824
Ensembl: ENSNLEG00000015257
UniProt: G1RZ45
LinkDB
Position
7b:complement(10978517..10980946)
AA seq 351 aa
MTEMSFLSSKVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFRPHGFSSDKAKAGSSE
WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDFDALLGIDDLETMPDDLLTTLDDTC
DLFDPLVQETNKEPPQTVNPIGHLPESLIKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
ELGSEVDITEGDRKPDSTAYVVMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEDVRKARGKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgaccgaaatgagcttcctgagcagcaaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggaaagcctaggtctcttagatgactacctggaggtg
gccaagcacttcagacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtccttccaacaacagcaaggaggatgccttctcc
gggacagattggatgttggagaaaatggatttgaaggagttcgactttgatgccctgttg
ggtatagatgacctggaaaccatgccagatgaccttttgaccactttggatgacacttgt
gatctctttgaccctctagtccaggagactaataaggagcccccccagacggtgaaccca
attggccatctcccagaaagtttaataaaacccgaccaggttgcccccttcaccttcttg
caacctcttcccctttccccaggagtcctgtcctccactccagatcattcctttagttta
gagctgggcagtgaagtggatatcactgaaggagataggaagccagactccactgcttac
gttgtcatgatccctcagtgcataaaggaggaagacaccccttcagataatgatagtgga
atatgtatgagcccagagtcgtatctggggtctcctcagcatagcccttctaccaggggc
tctccaaataggagtctcccatctccaggtgttctctgtgggtctgcccgccccaaacct
tacgatcctcctggagagaagatggtagcagcaaaagtaaagggtgagaaattggataag
aagctgaaaaaaatggagcaaaacaagacagcagccactaggtaccgccagaagaagagg
gcggagcaggaggctctcactggcgagtgcaaagagctagaaaagaagaacgaggctcta
aaagagagggcggattccctggccaaggagatccagtacttgaaagatttgatagaagat
gtccgcaaggcacgggggaagaaaagggtcccctag

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