| Entry |
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| Symbol |
ATF4
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| Name |
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
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| KO |
| K04374 | cyclic AMP-dependent transcription factor ATF-4 |
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| Organism |
nle Nomascus leucogenys (northern white-cheeked gibbon)
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| Pathway |
| nle04141 | Protein processing in endoplasmic reticulum |
| nle04261 | Adrenergic signaling in cardiomyocytes |
| nle04925 | Aldosterone synthesis and secretion |
| nle04927 | Cortisol synthesis and secretion |
| nle04928 | Parathyroid hormone synthesis, secretion and action |
| nle04932 | Non-alcoholic fatty liver disease |
| nle04935 | Growth hormone synthesis, secretion and action |
| nle05022 | Pathways of neurodegeneration - multiple diseases |
| nle05163 | Human cytomegalovirus infection |
| nle05166 | Human T-cell leukemia virus 1 infection |
| nle05207 | Chemical carcinogenesis - receptor activation |
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| Brite |
KEGG Orthology (KO) [BR:nle00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100588160 (ATF4)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100588160 (ATF4)
04668 TNF signaling pathway
100588160 (ATF4)
04022 cGMP-PKG signaling pathway
100588160 (ATF4)
04151 PI3K-Akt signaling pathway
100588160 (ATF4)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
100588160 (ATF4)
09143 Cell growth and death
04210 Apoptosis
100588160 (ATF4)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100588160 (ATF4)
04922 Glucagon signaling pathway
100588160 (ATF4)
04912 GnRH signaling pathway
100588160 (ATF4)
04915 Estrogen signaling pathway
100588160 (ATF4)
04926 Relaxin signaling pathway
100588160 (ATF4)
04935 Growth hormone synthesis, secretion and action
100588160 (ATF4)
04918 Thyroid hormone synthesis
100588160 (ATF4)
04928 Parathyroid hormone synthesis, secretion and action
100588160 (ATF4)
04925 Aldosterone synthesis and secretion
100588160 (ATF4)
04927 Cortisol synthesis and secretion
100588160 (ATF4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100588160 (ATF4)
09156 Nervous system
04725 Cholinergic synapse
100588160 (ATF4)
04728 Dopaminergic synapse
100588160 (ATF4)
04720 Long-term potentiation
100588160 (ATF4)
04722 Neurotrophin signaling pathway
100588160 (ATF4)
09149 Aging
04211 Longevity regulating pathway
100588160 (ATF4)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100588160 (ATF4)
05203 Viral carcinogenesis
100588160 (ATF4)
09162 Cancer: specific types
05215 Prostate cancer
100588160 (ATF4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100588160 (ATF4)
05161 Hepatitis B
100588160 (ATF4)
05163 Human cytomegalovirus infection
100588160 (ATF4)
09164 Neurodegenerative disease
05010 Alzheimer disease
100588160 (ATF4)
05012 Parkinson disease
100588160 (ATF4)
05014 Amyotrophic lateral sclerosis
100588160 (ATF4)
05020 Prion disease
100588160 (ATF4)
05022 Pathways of neurodegeneration - multiple diseases
100588160 (ATF4)
09165 Substance dependence
05030 Cocaine addiction
100588160 (ATF4)
05031 Amphetamine addiction
100588160 (ATF4)
05034 Alcoholism
100588160 (ATF4)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100588160 (ATF4)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100588160 (ATF4)
04934 Cushing syndrome
100588160 (ATF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:nle03000]
100588160 (ATF4)
Transcription factors [BR:nle03000]
Eukaryotic type
Basic leucine zipper (bZIP)
AP-1(-like) components, CRE-BP/ATF
100588160 (ATF4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
7b:complement(10978517..10980946)
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| AA seq |
351 aa
MTEMSFLSSKVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFRPHGFSSDKAKAGSSE
WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDFDALLGIDDLETMPDDLLTTLDDTC
DLFDPLVQETNKEPPQTVNPIGHLPESLIKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
ELGSEVDITEGDRKPDSTAYVVMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEDVRKARGKKRVP |
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| NT seq |
1056 nt +upstreamnt +downstreamnt
atgaccgaaatgagcttcctgagcagcaaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggaaagcctaggtctcttagatgactacctggaggtg
gccaagcacttcagacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtccttccaacaacagcaaggaggatgccttctcc
gggacagattggatgttggagaaaatggatttgaaggagttcgactttgatgccctgttg
ggtatagatgacctggaaaccatgccagatgaccttttgaccactttggatgacacttgt
gatctctttgaccctctagtccaggagactaataaggagcccccccagacggtgaaccca
attggccatctcccagaaagtttaataaaacccgaccaggttgcccccttcaccttcttg
caacctcttcccctttccccaggagtcctgtcctccactccagatcattcctttagttta
gagctgggcagtgaagtggatatcactgaaggagataggaagccagactccactgcttac
gttgtcatgatccctcagtgcataaaggaggaagacaccccttcagataatgatagtgga
atatgtatgagcccagagtcgtatctggggtctcctcagcatagcccttctaccaggggc
tctccaaataggagtctcccatctccaggtgttctctgtgggtctgcccgccccaaacct
tacgatcctcctggagagaagatggtagcagcaaaagtaaagggtgagaaattggataag
aagctgaaaaaaatggagcaaaacaagacagcagccactaggtaccgccagaagaagagg
gcggagcaggaggctctcactggcgagtgcaaagagctagaaaagaagaacgaggctcta
aaagagagggcggattccctggccaaggagatccagtacttgaaagatttgatagaagat
gtccgcaaggcacgggggaagaaaagggtcccctag |
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