Nomascus leucogenys (northern white-cheeked gibbon): 100588621
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Entry
100588621 CDS
T03265
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X2
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04066
HIF-1 signaling pathway
nle04137
Mitophagy - animal
nle04140
Autophagy - animal
nle04148
Efferocytosis
nle04659
Th17 cell differentiation
nle04919
Thyroid hormone signaling pathway
nle05167
Kaposi sarcoma-associated herpesvirus infection
nle05200
Pathways in cancer
nle05205
Proteoglycans in cancer
nle05208
Chemical carcinogenesis - reactive oxygen species
nle05211
Renal cell carcinoma
nle05230
Central carbon metabolism in cancer
nle05231
Choline metabolism in cancer
nle05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100588621 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100588621 (HIF1A)
04137 Mitophagy - animal
100588621 (HIF1A)
04148 Efferocytosis
100588621 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100588621 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100588621 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100588621 (HIF1A)
05205 Proteoglycans in cancer
100588621 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
100588621 (HIF1A)
05230 Central carbon metabolism in cancer
100588621 (HIF1A)
05231 Choline metabolism in cancer
100588621 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100588621 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
100588621 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
100588621 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
nle03000
]
100588621 (HIF1A)
Transcription factors [BR:
nle03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
100588621 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
100588621
NCBI-ProteinID:
XP_003267827
Ensembl:
ENSNLEG00000013874
UniProt:
G1RUP5
LinkDB
All DBs
Position
1a:78602573..78655583
Genome browser
AA seq
826 aa
AA seq
DB search
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGREQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET
DDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTSETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTVT
VFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYR
DTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKR
KMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLAC
RLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2481 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa
aagtctcgagatgcagccagatctcggcgaagtaaagaatctgaagttttttatgagctt
gctcatcagttgccacttccacataatgtgagttcgcatcttgataaggcctctgttatg
aggcttaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttggatatt
gaagatgaaatgaaagcacagatgaattgcttttatttgaaagccttggatggttttgtt
atggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatacatg
ggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacacacagaaatggccctgtgaaaaagggtagagaa
caaaacacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgaggaaga
actatgaacataaagtctgcaacatggaaggtattgcactgcacaggccatattcacgta
tatgataccaacagtaaccaacctcagtgtgggtataagaaaccacctatgacctgcttg
gtgctgatttgtgaacccattcctcacccatcaaatattgaaattcctttagatagcaag
actttcctcagtcgacacagcctggatatgaaattttcttattgtgacgaaagaattacc
gaattgatgggatatgagccagaagaacttttaggccgctcaatttatgaatattatcat
gctttggactctgatcatctgaccaaaactcatcatgatatgtttactaaaggacaagtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaactgtcatatataacaccaagaactctcaaccacagtgcattgtatgtgtgaattat
gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
cttaaaccggttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca
gaagacacaagtagcctctttgacaaacttaagaaggaacctgatgctttaactttgctg
gccccagccgctggagacacaatcatatctttagattttggcagcaacgacacagaaact
gatgaccagcaacttgaggaagtaccattgtataatgatgtaatgctcccctcacccaac
gaaaaattacagaatataaatttggcaatgtctccattacccacctctgaaacaccaaag
ccgcttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagaacca
aatccagagtcactggaactttcttttaccatgccccagattcaggatcagccacctagt
ccttctgatggaagcactagacaaagttcacctgagcctaatagtcccagtgaatattgt
ttttatgtggatagtgatatggtcaatgaattcaagttggaattggtagaaaaacttttt
gctgaagacacagaagcaaagaacccattttccactcaggacacagatttagacttggag
atgttagctccctatatcccaatggatgatgacttccagttacgttccttcgatcagttg
tcaccattagaaagcagttccgcaagccctgaaagcgcaagtcctcaaagcacagttaca
gtattccagcagactcaaatacaagaacctactgctaatgccaccactaccactgccacc
actgatgaattaaaaacagtgacaaaagaccgtatggaagacattaagatattgattgca
tctccatctcctacccacatacataaagaaactactagtgccacgtcatcaccatataga
gatactcaaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacagaca
gaaaaatctcatccaagaagccctaacgtgttatctgtcgctttgagtcaaagaactaca
gttcctgaggaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcga
aaaatggaacatgatggttcactttttcaagcagtaggaattggaacattattacagcag
ccagacgatcatgcagctactacatcactttcttggaaacgtgtaaaaggatgcaaatct
agtgaacagaatggaatggagcaaaagacaattattttaataccctctgatttagcatgt
agactgctggggcaatcaatggatgaaagtggattaccacagctgaccagttatgattgt
gaagttaatgctcctatacaaggcagcagaaacctactgcagggtgaagaattactcaga
gctttggatcaagttaactga
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