Nomascus leucogenys (northern white-cheeked gibbon): 100589003
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Entry
100589003 CDS
T03265
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00220
Arginine biosynthesis
nle00330
Arginine and proline metabolism
nle01100
Metabolic pathways
nle04020
Calcium signaling pathway
nle04066
HIF-1 signaling pathway
nle04146
Peroxisome
nle04371
Apelin signaling pathway
nle04926
Relaxin signaling pathway
nle05010
Alzheimer disease
nle05014
Amyotrophic lateral sclerosis
nle05022
Pathways of neurodegeneration - multiple diseases
nle05133
Pertussis
nle05140
Leishmaniasis
nle05142
Chagas disease
nle05145
Toxoplasmosis
nle05146
Amoebiasis
nle05152
Tuberculosis
nle05200
Pathways in cancer
nle05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100589003 (NOS2)
00330 Arginine and proline metabolism
100589003 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
100589003 (NOS2)
04066 HIF-1 signaling pathway
100589003 (NOS2)
04020 Calcium signaling pathway
100589003 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100589003 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
100589003 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100589003 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
100589003 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
100589003 (NOS2)
05152 Tuberculosis
100589003 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100589003 (NOS2)
05145 Toxoplasmosis
100589003 (NOS2)
05140 Leishmaniasis
100589003 (NOS2)
05142 Chagas disease
100589003 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
100589003 (NOS2)
05014 Amyotrophic lateral sclerosis
100589003 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
100589003 (NOS2)
Enzymes [BR:
nle01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100589003 (NOS2)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DUF1400
Motif
Other DBs
NCBI-GeneID:
100589003
NCBI-ProteinID:
XP_003277133
Ensembl:
ENSNLEG00000001492
UniProt:
G1QMC7
LinkDB
All DBs
Position
19:38736713..38781068
Genome browser
AA seq
1153 aa
AA seq
DB search
MACPWKFLFKTKFHHYAMNGEKDINNNVEKASCATSSPVTQDDLQYHRLSKQQNESPQPF
VETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIM
TPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYSTNNGNI
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG
RFDVVPLVLQADGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVG
GLEFPACPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINI
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEM
LNYVLSPFYYYQVEAWKTHVWQDEKRRPRRREIPLKVLVKAVLFACMLMRKTMASRVRVT
ILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPS
NGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPTGEGD
ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHRYRLVQDSQPLDL
SKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEEGQGLNYLPGEHLGVFPGNQ
PALVQGILERVVDNPAPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQ
LLLQKLAQVATEDPERQRLEALCQPSEYSKWKFTNSLTFLEVLEEFPSLRVSADFLLSQL
PILKPRFYSISSSQDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCF
VRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPD
EDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHEEPGHLY
VCGDVRMARDVAHTLKQLVAAKLKLNEEQAEDYFFQLKSQKRYHEDIFGAVFPYEVKKDR
AAVQPSSLEMSAL
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtccttggaaatttctgttcaagaccaaattccaccactatgcaatgaatgga
gaaaaagacatcaacaacaacgtggagaaagcctcctgtgccacctccagtccagtgaca
caggatgacctccagtatcacaggctcagcaagcagcagaatgagtccccgcagcccttc
gtggagacgggaaagaagtctccagaatctctggtcaagctggatgcgaccccattgtcc
tccccacggcatgtgaggatcaaaaactggggcagtgggatgactttccaagacacactt
caccacaaggccaaagggattttgacttgcaggtccaaatcttgcctggggtccattatg
actcccaaaagtttgaccagaggacccagggacaagcctacccctccagatgagcttcta
cctcaagctatcgaatttgtcaaccaatattacggctccttcaaagaggcaaaaatagag
gaacatctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctaccaa
ctgacgggagatgagctcatcttcgccaccaagcaggcctggcgcaatgccccacgctgc
attgggaggatccagtggtccaacctgcaggtctttgatgcccgcagctgttccaccgcc
caggaaatgtttgaacacatctgcagacacgtgcgttactccaccaacaatggcaacatc
aggtcggccatcaccgtgttcccccagcggagtgatggcaagcacgacttccgggtgtgg
aatgctcagctcatccgctatgctggctaccagatgccagatggcagcatcagaggggac
cctgccaacgtggaattcactcagctgtgcatcgacctgggctggaagcccaagtacggc
cgcttcgatgtggtccccctggtcctgcaggccgatggccgtgaccctgagctcttcgaa
atcccacctgaccttgtgcttgaggtggccatggaacatcctaaatacgagtggtttcgg
gaactggagctaaagtggtacgccctgcctgcagtggccaacatgctgctcgaggtgggc
ggcctggagttcccagcgtgccccttcaatggctggtacatgggcacagagatcggagtc
cgggacttctgtgacgtccagcgctacaacatcctggaggaagtgggcaggagaatgggc
ttggaaacgcacaagctggcctcgctctggaaagaccaggctgtcgttgagatcaacatt
gctgtgctccatagtttccagaagcagaatgtgaccatcatggaccaccactcggctgca
gaatccttcatgaagtacatgcagaatgaataccggtcccgtgggggctgcccggcagac
tggatttggctggtccctcccatgtctgggagcatcacccccgtgtttcaccaggagatg
ctgaactatgtcctgtcccctttctactactatcaggtagaggcctggaaaacccatgtc
tggcaggacgagaagcggagacccaggagaagagagattccattgaaagtcttggtgaaa
gctgtgctctttgcctgtatgctgatgcgcaagacaatggcgtcccgagtcagagtcacc
atcctctttgcgacagagacaggaaaatcagaggcgctggcctgggatctgggggccttg
ttcagctgtgccttcaatcccaaggttgtctgcatggataagtacaggctgagctgcctg
gaggaagagcggctgctgttggtggtgaccagtacctttggcaatggagactgccccagc
aatggagagaaactgaagaaatcgctcttcatgctgaaagagctcaacaacaaattcagg
tacgctgtgtttggcctcggctccagcatgtaccctcggttctgcgcctttgctcatgac
attgatcagaagctgtcccacctgggggcctctcagctcaccccgactggagaaggggat
gagctcagcgggcaggaggatgccttccgcagctgggccgtgcaaaccttcaaggcagcc
tgtgagacgtttgatgtccgaggcaaacagcacattcagatccccaagctctacacctcc
aacgtgacctgggacccgcaccgctacaggcttgtgcaggactcacagcctttggacctc
agcaaagccctcagcagcatgcacgccaagaatgtgttcaccatgaggctcaaatctcgg
cagaatctacagagtccaacatccagccgtgccaccatcctggtggaactctcctgtgag
gagggccaaggcctgaactacctgccgggggagcatcttggggttttcccaggcaaccag
ccggccctcgtccaaggcatcctggagcgagtggtggacaaccctgcgccccaccagaca
gtgcgcctggaggccctggatgagagcggcagctactgggtcagtgacaagaggctgccc
ccctgctcactcagccaggccctcacctacttcctggacatcaccactcccccgacccag
ctgctgctccaaaagctggcccaggtggccacagaagacccggagagacagaggctggag
gccttgtgtcagccctcagagtacagcaagtggaagttcaccaacagcctcacgttcctg
gaggtgctagaggagttcccatccctgcgggtgtctgctgacttcctgctttcccagctc
cccattctgaagcccaggttctactctatcagctcctcccaggatcacacgcccacagag
atccacctgactgtggccgtggtcacctaccacacccgagatggccagggtcccctgcac
catggcgtctgcagcacatggctcaacagcctgaagccccaagacccagtgccctgcttt
gtgcggaatgccagcggcttccacctccccgaggacccctcccatccttgcatcctcatc
gggcctggcacaggcatcgcgcccttccgcagtttctggcagcagcggctccatgactcc
cagcacaagggagtgcggggaggccggatgaccttggtgtttgggtgccgccgcccagat
gaagaccacatctaccaggaggagatgctggagatggcccagaagggggtgctgcatgcg
gtgcacacagcctattcccgtctgcctggcaagcccaaggtctatgttcaggacatcctg
cggcagcagctggccagcgaggtgctccgtgtgctccatgaggagccgggccacctctat
gtttgcggggatgtgcgcatggcccgggacgtggcccacaccctgaagcagctggtggct
gccaagctgaaactgaatgaggagcaggctgaggactatttctttcagctcaagagccag
aagcgctatcatgaagatatctttggtgctgtatttccctacgaggtgaagaaggacagg
gcagcggtgcagcccagcagcctggagatgtcagcgctctga
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