Nomascus leucogenys (northern white-cheeked gibbon): 100590165
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Entry
100590165 CDS
T03265
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521
EGFR tyrosine kinase inhibitor resistance
nle01522
Endocrine resistance
nle04010
MAPK signaling pathway
nle04012
ErbB signaling pathway
nle04014
Ras signaling pathway
nle04062
Chemokine signaling pathway
nle04068
FoxO signaling pathway
nle04072
Phospholipase D signaling pathway
nle04150
mTOR signaling pathway
nle04151
PI3K-Akt signaling pathway
nle04510
Focal adhesion
nle04540
Gap junction
nle04630
JAK-STAT signaling pathway
nle04650
Natural killer cell mediated cytotoxicity
nle04660
T cell receptor signaling pathway
nle04662
B cell receptor signaling pathway
nle04664
Fc epsilon RI signaling pathway
nle04714
Thermogenesis
nle04722
Neurotrophin signaling pathway
nle04810
Regulation of actin cytoskeleton
nle04910
Insulin signaling pathway
nle04912
GnRH signaling pathway
nle04915
Estrogen signaling pathway
nle04917
Prolactin signaling pathway
nle04926
Relaxin signaling pathway
nle04935
Growth hormone synthesis, secretion and action
nle05034
Alcoholism
nle05160
Hepatitis C
nle05161
Hepatitis B
nle05163
Human cytomegalovirus infection
nle05165
Human papillomavirus infection
nle05200
Pathways in cancer
nle05205
Proteoglycans in cancer
nle05206
MicroRNAs in cancer
nle05207
Chemical carcinogenesis - receptor activation
nle05208
Chemical carcinogenesis - reactive oxygen species
nle05210
Colorectal cancer
nle05211
Renal cell carcinoma
nle05213
Endometrial cancer
nle05214
Glioma
nle05215
Prostate cancer
nle05220
Chronic myeloid leukemia
nle05221
Acute myeloid leukemia
nle05223
Non-small cell lung cancer
nle05224
Breast cancer
nle05225
Hepatocellular carcinoma
nle05226
Gastric cancer
nle05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100590165 (SOS1)
04012 ErbB signaling pathway
100590165 (SOS1)
04014 Ras signaling pathway
100590165 (SOS1)
04630 JAK-STAT signaling pathway
100590165 (SOS1)
04068 FoxO signaling pathway
100590165 (SOS1)
04072 Phospholipase D signaling pathway
100590165 (SOS1)
04151 PI3K-Akt signaling pathway
100590165 (SOS1)
04150 mTOR signaling pathway
100590165 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100590165 (SOS1)
04540 Gap junction
100590165 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100590165 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100590165 (SOS1)
04660 T cell receptor signaling pathway
100590165 (SOS1)
04662 B cell receptor signaling pathway
100590165 (SOS1)
04664 Fc epsilon RI signaling pathway
100590165 (SOS1)
04062 Chemokine signaling pathway
100590165 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
100590165 (SOS1)
04912 GnRH signaling pathway
100590165 (SOS1)
04915 Estrogen signaling pathway
100590165 (SOS1)
04917 Prolactin signaling pathway
100590165 (SOS1)
04926 Relaxin signaling pathway
100590165 (SOS1)
04935 Growth hormone synthesis, secretion and action
100590165 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
100590165 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
100590165 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100590165 (SOS1)
05206 MicroRNAs in cancer
100590165 (SOS1)
05205 Proteoglycans in cancer
100590165 (SOS1)
05207 Chemical carcinogenesis - receptor activation
100590165 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
100590165 (SOS1)
05231 Choline metabolism in cancer
100590165 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
100590165 (SOS1)
05225 Hepatocellular carcinoma
100590165 (SOS1)
05226 Gastric cancer
100590165 (SOS1)
05214 Glioma
100590165 (SOS1)
05221 Acute myeloid leukemia
100590165 (SOS1)
05220 Chronic myeloid leukemia
100590165 (SOS1)
05211 Renal cell carcinoma
100590165 (SOS1)
05215 Prostate cancer
100590165 (SOS1)
05213 Endometrial cancer
100590165 (SOS1)
05224 Breast cancer
100590165 (SOS1)
05223 Non-small cell lung cancer
100590165 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
100590165 (SOS1)
05160 Hepatitis C
100590165 (SOS1)
05163 Human cytomegalovirus infection
100590165 (SOS1)
05165 Human papillomavirus infection
100590165 (SOS1)
09165 Substance dependence
05034 Alcoholism
100590165 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100590165 (SOS1)
01522 Endocrine resistance
100590165 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
100590165
NCBI-ProteinID:
XP_003262811
Ensembl:
ENSNLEG00000016450
UniProt:
G1S388
LinkDB
All DBs
Position
19:47687574..47828461
Genome browser
AA seq
1332 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
QTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHR
DGPPLLENAHSS
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccctacgagtttttcagcgaagagaacgcgcccaagtggcgg
ggattgctggtgcctgcgctgaaaaaggtccaggggcaagttcatcctactctcgagtct
aacgatgatgctcttcagtatgttgaagaattaattttgcaattattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
cctattgataagtgggcaatagctgatgcccaatcagctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtcttagaatacatttctgcagac
attttaaagctggttgggaattatgtaagaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgacaaggtattgatggatatgtttcatcaagatgta
gaagatattaatatattatctttaactgatgaagagccttccacctcaggagaacaaact
tactatgatttggtaaaagcatttatggcagaaattcgacaatatataagggaactaaat
ctaattataaaagtttttagagagccctttgtctccaattcaaaactgttttcagctaat
gatgtagaaaatatatttagtcgcatagtagatatacatgaacttagcgtaaagttactg
ggccatatagaagatacagtagaaatgacagatgaaggcagtccccatcctctagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcgtatgctcga
gatattttgcgacctggttttcatgatcgtttccttagtcagttatcaaagcctggggca
gcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcaatatgttttaccc
aggctacttctggcccctgtttaccactgtctccattactttgaacttttgaagcagtta
gaagaaaaaagtgaagatcaagaagacaaggaatgtttaaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatccgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcgaaaggtacaa
attaatgataaagatgacaccaatgaatacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtaacaatgctacag
gaagagaaagaggagcagatgaggctgcctagtgctgatgtttatagatttgcagagcct
gactctgaagagaatattatatttgaagagaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggcttacgtaccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgcaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagaactaaaaagatttagaaaagaa
tatatacagcctgtgcaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctatgattttgaaagagatgcatatcttttgcaacgaatggaagaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatatcacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctataccgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaactctcctaat
cttctgaaaatgattcgacataccaccaacctcactctgtggtttgagaaatgtattgta
gaaactgaaaatttagaagaaagggtagctgtggtgagtcgaataattgagattctacaa
gtctttcaagagttgaacaactttaatggtgtccttgaggttgtcagtgctatgaattca
tcacctgtttacagactagaccacacatttgagcaaataccaagtcgccagaagaaaatt
ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctcactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaagacatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttactgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccgatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgaggcatcccacacctctgcagcaggagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctccgcctgcttctggtgcttccagtaccacagat
gtttgcagtgtatttgattccgatcattcgagcccttttcactcaagcaatgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttctgtatcatctataagttta
accaaaggcactgatgaagtgcctgtccctcctcctgttcctccacgaagacgaccagaa
tctgccccagcagaatcttcaccatctaagattatgtctaagcatttggacagcccccca
gccattcctcctaggcaacccacatcaaaagcctattcaccacgatattcaatatcagac
cggacctctatctcagaccctcctgaaagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggtaaa
aaaagtgatcatggcaatgccttcttcccaaacagcccttccccctttacaccacctcct
caaacaccttctcctcacggcacaagaaggcatctgccatcaccaccattgacacaagaa
gtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcaacat
atccctaaactccctccaaaaacttacaaaagggagcacacacacccatccatgcacaga
gatggaccaccactgttggagaatgcccattcttcctga
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integrated database retrieval system
