KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100591033
Entry
100591033         CDS       T03265                                 
Symbol
HDAC1
Name
(RefSeq) histone deacetylase 1 isoform X3
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle03082  ATP-dependent chromatin remodeling
nle03083  Polycomb repressive complex
nle04110  Cell cycle
nle04213  Longevity regulating pathway - multiple species
nle04330  Notch signaling pathway
nle04350  TGF-beta signaling pathway
nle04613  Neutrophil extracellular trap formation
nle04919  Thyroid hormone signaling pathway
nle05016  Huntington disease
nle05031  Amphetamine addiction
nle05034  Alcoholism
nle05165  Human papillomavirus infection
nle05169  Epstein-Barr virus infection
nle05200  Pathways in cancer
nle05202  Transcriptional misregulation in cancer
nle05203  Viral carcinogenesis
nle05206  MicroRNAs in cancer
nle05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:nle00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    100591033 (HDAC1)
   03083 Polycomb repressive complex
    100591033 (HDAC1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    100591033 (HDAC1)
   04350 TGF-beta signaling pathway
    100591033 (HDAC1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100591033 (HDAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100591033 (HDAC1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    100591033 (HDAC1)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    100591033 (HDAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100591033 (HDAC1)
   05202 Transcriptional misregulation in cancer
    100591033 (HDAC1)
   05206 MicroRNAs in cancer
    100591033 (HDAC1)
   05203 Viral carcinogenesis
    100591033 (HDAC1)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    100591033 (HDAC1)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    100591033 (HDAC1)
   05165 Human papillomavirus infection
    100591033 (HDAC1)
  09164 Neurodegenerative disease
   05016 Huntington disease
    100591033 (HDAC1)
  09165 Substance dependence
   05031 Amphetamine addiction
    100591033 (HDAC1)
   05034 Alcoholism
    100591033 (HDAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:nle03036]
    100591033 (HDAC1)
Enzymes [BR:nle01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     100591033 (HDAC1)
Chromosome and associated proteins [BR:nle03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     100591033 (HDAC1)
   HDAC complexes
    Sin3A-HDAC complex
     100591033 (HDAC1)
    BRAF-HDAC complex
     100591033 (HDAC1)
    REST complex
     100591033 (HDAC1)
    SHIP complex
     100591033 (HDAC1)
    MiDAC complex
     100591033 (HDAC1)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     100591033 (HDAC1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    100591033 (HDAC1)
  Chromatin remodeling factors
   NuRD complex
    100591033 (HDAC1)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 100591033
NCBI-ProteinID: XP_003276411
Ensembl: ENSNLEG00000002473
UniProt: G1QQE9
LinkDB
Position
12:1518845..1559920
AA seq 482 aa
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN
AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS
AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG
DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG
GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE
KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEF
SDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDSEEKKEVTEEEKTKEEKPEAKGVKEEVK
LA
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggcgcagacgcagggcacccggaggaaagtctgttactactacgacggggatgttgga
aattactattatggacaaggccacccaatgaagcctcaccgaatccgcatgactcataat
ttgctgctcaactatggtctctaccgaaagatggaaatctatcgccctcacaaagccaat
gccgaggagatgaccaagtaccacagcgatgactacattaaattcttgcgctccatccgt
ccagataacatgtcggagtacagcaagcagatgcagagattcaacgttggtgaggactgt
ccagtattcgatggcctgtttgagttctgtcagttgtctactggtggttctgtggcaagt
gctgtgaaacttaataagcagcagacggacatcgctgtgaattgggctgggggcctgcac
catgcaaagaagtccgaggcatctggcttctgttacgtcaatgatatcgtcttggctatc
ctggaactgctgaagtatcaccagagggtgctgtatattgacattgatattcaccatggc
gacggcgtggaagaggccttctataccacagaccgggtcatgactgtgtcttttcataag
tatggagagtacttcccaggaactggggacctacgggatatcggggctggcaaaggcaag
tattatgctgttaactacccgctccgagacgggattgatgacgagtcctatgaggccatt
ttcaagccggtcatgtccaaagtaatggagatgttccagcctagcgcggtggtcttacag
tgtggctcagactccctgtctggggaccggttaggttgcttcaatctaactatcaaaggg
catgccaagtgtgtggaatttgtcaagagctttaacctgcctatgctgatgctgggaggc
ggtggttacaccattcgtaatgttgcccggtgctggacatacgagacagctgtggccctg
gatacggagatccctaatgagcttccatacaacgactactttgaatactttggaccagat
ttcaagctccacatcagtccttccaatatgactaaccagaacacaaatgagtacctggag
aagatcaaacagcgactgtttgagaaccttagaatgctgccgcatgcacccggggtccag
atgcaggcgattcctgaggacgccatccctgaggagagtggcgatgaggacgaagaagac
cctgacaagcgcatctcgatctgctcctctgacaaacgaattgcctgtgaggaagagttc
tccgattctgaagaggagggagaggggggccgcaagaactcttccaacttcaaaaaagcc
aagagagtcaagacagaggatgagaaagagaaagactcagaggagaagaaagaagtcaca
gaagaggagaaaaccaaggaggagaagccagaagccaaaggggtcaaggaggaggtcaag
ttggcctga

DBGET integrated database retrieval system