Nomascus leucogenys (northern white-cheeked gibbon): 100592456
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Entry
100592456 CDS
T03265
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00220
Arginine biosynthesis
nle00330
Arginine and proline metabolism
nle01100
Metabolic pathways
nle04020
Calcium signaling pathway
nle04022
cGMP-PKG signaling pathway
nle04066
HIF-1 signaling pathway
nle04071
Sphingolipid signaling pathway
nle04151
PI3K-Akt signaling pathway
nle04370
VEGF signaling pathway
nle04371
Apelin signaling pathway
nle04611
Platelet activation
nle04915
Estrogen signaling pathway
nle04921
Oxytocin signaling pathway
nle04926
Relaxin signaling pathway
nle04931
Insulin resistance
nle04933
AGE-RAGE signaling pathway in diabetic complications
nle05415
Diabetic cardiomyopathy
nle05417
Lipid and atherosclerosis
nle05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100592456 (NOS3)
00330 Arginine and proline metabolism
100592456 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100592456 (NOS3)
04371 Apelin signaling pathway
100592456 (NOS3)
04066 HIF-1 signaling pathway
100592456 (NOS3)
04020 Calcium signaling pathway
100592456 (NOS3)
04071 Sphingolipid signaling pathway
100592456 (NOS3)
04022 cGMP-PKG signaling pathway
100592456 (NOS3)
04151 PI3K-Akt signaling pathway
100592456 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100592456 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100592456 (NOS3)
04921 Oxytocin signaling pathway
100592456 (NOS3)
04926 Relaxin signaling pathway
100592456 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100592456 (NOS3)
05418 Fluid shear stress and atherosclerosis
100592456 (NOS3)
05415 Diabetic cardiomyopathy
100592456 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100592456 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100592456 (NOS3)
Enzymes [BR:
nle01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100592456 (NOS3)
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GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100592456
NCBI-ProteinID:
XP_030682013
Ensembl:
ENSNLEG00000003964
LinkDB
All DBs
Position
13:99126154..99147845
Genome browser
AA seq
1203 aa
AA seq
DB search
MGNLNSVAKEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT
QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCHGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFLLPPELILEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
RDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQCGVFGRVLTAFSRE
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPLGSDT
NSP
NT seq
3612 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaacagcgtggccaaggagcctgggccaccctgcggcctggggctgggg
ctgggcctcgggctgtgcggcaagcagggcccagccaccccggcccctgagcccagccgg
gccccggcatccctactcccgccagcgccagaacacagccccccgagctccccactaacc
cagcccccagaggggcccaagttccctcgtgtgaagaactgggaggtggggagcatcacc
tatgacaccctcagcgcccaggcgcaacaggatgggccctgcaccccaagacgctgcctg
ggctccctggtatttccacggaaactacagggccggccctcccccggccccccggcccct
gagcagctgctaagtcaggcccgcgacttcatcaaccagtactacagctccatcaagagg
agcggctcccaggcccacgaacagcggcttcaagaggtggaagccgaggtggcagccaca
ggcacctaccagcttagggagagtgagctggtgttcggggccaagcaggcctggcgcaac
gctccccgctgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggac
tgcaggtctgcacaggaaatgttcacctacatctgtaaccacatcaagtatgccaccaac
cggggcaaccttcgctcggccatcacagtgttcccgcagcgctgccatggccgaggagac
ttccgaatctggaacagccagctggtgcgctatgcgggctaccggcagcaggacggctct
gtgcggggggacccagccaacgtggagatcaccgagctctgcattcagcacggctggacc
ccaggaaacggtcgcttcgacgtgctgccactgctgctgcaggccccagatgagccccca
gaactcttccttctgccccccgagctgatccttgaggtgcccctggagcaccccacgctg
gagtggtttgcagccctgggcctgcgctggtacgccctcccggcagtgtccaacatgctg
ctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcact
gagattggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggatgtggct
gtctgcatggacctggatacccggacaacctcgtccctgtggaaagacaaggcagcagtg
gaaatcaatgtggccgtgctgcacagttaccagctggccaaagtcacaatcgtggaccac
cacgccgccacggcctccttcatgaagcatctggagaatgagcagaaggccagggggggc
tgccctgcagactgggcctggatcgtgccccctatctcaggcagcctcactcctgtcttc
catcaggagatggtcaactatttcctgtccccagccttccgatatcagccagacccctgg
aaggggagtgccgccaagggcactggcatcaccaggaagaagaccttcaaagaagtggcc
aacgccgtgaagatctccgcctcgctcatgggcacagtgatggcgaagcgagtaaaggcg
acaatcctgtatggctccgagaccggccgggcccagagctacgcacagcagctggggaga
ctcttccggaaggcttttgatccccgggtcctatgtatggatgagtatgacgtggtgtcc
cttgaacacgagacgctggtgctggtagtaaccagcacatttgggaatggggatccgccg
gagaatggagagagctttgcagctgccctgatggagatgtccggcccctacaacagctcc
cctcggccggaacagcacaagagttataagatccgcttcaacagcatctcctgctcagac
ccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggg
gccctgggcaccctcaggttctgtgtgttcgggctgggctcccgggcatacccccacttc
tgcgcctttgctcgtgcggtggacacacggctggaggaactgggcggggagcggctgctg
cagctgggccagggcgacgagctgtgcggccaggaggaggccttccgcggctgggcccag
gccgccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaaggccgccgcc
cgagatatcttcagccccaaacggagctggaagcgccagaggtaccggctgagcgcccag
gccgagggcctgcagttgctgccaggtctgatccacgtgcacagacggaagatgttccag
gctacaatcctctcagtggaaaacctgcaaagcagcaagtccacgagggccaccatcctg
gtgcgcctggacaccggaggccaggaggggctgcagtaccagccgggggaccacataggt
gtctgcccacccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccg
ccggcgcccactgagcccgtggcagtagagcagctggagaagggcagccctggtggccct
ccccccggctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctcacc
ttcttcctggacatcacctccccgcccagccctcagctcttgcggttgctcagcaccttg
gcagaagagcccagggaacagcaggagctggaggccctcagccaggatccccgacgctat
gaggagtggaagtggttccgctgtcccacgctgctggaggtgctggagcagttcccgtcg
gtggcactgcctgccccactgctcctcacccagctgcctctgctccagccccggtactac
tcagtcagctcggcacccagcacccacccaggagagatccacctcactgtagctgtgctg
gcatacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggctt
agccaactcaagcctggagaccctgtgccctgcttcatccggggggctccctccttccgg
ctgccacccgatcccagcttgccctgcatcctggtgggcccaggcactggcattgccccc
ttccggggattctggcaggagcggctgcatgacattgagagcaaagggctgcagcccact
cccatgactttggtgttcggctgccgatgctcccaactcgaccatctctaccgcgacgag
gtgcagaacgcccagcagtgcggggtgtttggccgagtcctcaccgccttctcccgggaa
cctgacaaccccaagacctacgtgcaggacatcctgaggacggaactggctgcggaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggca
accaacgtcctgcagaccgtgcagcgcatcctggcgacggagggcgacatggagctggac
gaagccggcgacgtcattggcgtgctgcgggatcagcaacgctaccacgaagacattttc
gggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttg
caggagcggcagttgcggggcgcagtgccctgggcgttcgacccgctcggctcagacacc
aacagcccctga
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integrated database retrieval system
