KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100595306
Entry
100595306         CDS       T03265                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X3
  KO
K05459  insulin-like growth factor 1
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521  EGFR tyrosine kinase inhibitor resistance
nle01522  Endocrine resistance
nle04010  MAPK signaling pathway
nle04014  Ras signaling pathway
nle04015  Rap1 signaling pathway
nle04066  HIF-1 signaling pathway
nle04068  FoxO signaling pathway
nle04081  Hormone signaling
nle04114  Oocyte meiosis
nle04115  p53 signaling pathway
nle04150  mTOR signaling pathway
nle04151  PI3K-Akt signaling pathway
nle04152  AMPK signaling pathway
nle04211  Longevity regulating pathway
nle04213  Longevity regulating pathway - multiple species
nle04510  Focal adhesion
nle04550  Signaling pathways regulating pluripotency of stem cells
nle04730  Long-term depression
nle04750  Inflammatory mediator regulation of TRP channels
nle04913  Ovarian steroidogenesis
nle04914  Progesterone-mediated oocyte maturation
nle04935  Growth hormone synthesis, secretion and action
nle04960  Aldosterone-regulated sodium reabsorption
nle05200  Pathways in cancer
nle05202  Transcriptional misregulation in cancer
nle05205  Proteoglycans in cancer
nle05214  Glioma
nle05215  Prostate cancer
nle05218  Melanoma
nle05224  Breast cancer
nle05410  Hypertrophic cardiomyopathy
nle05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100595306 (IGF1)
   04014 Ras signaling pathway
    100595306 (IGF1)
   04015 Rap1 signaling pathway
    100595306 (IGF1)
   04066 HIF-1 signaling pathway
    100595306 (IGF1)
   04068 FoxO signaling pathway
    100595306 (IGF1)
   04151 PI3K-Akt signaling pathway
    100595306 (IGF1)
   04152 AMPK signaling pathway
    100595306 (IGF1)
   04150 mTOR signaling pathway
    100595306 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100595306 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100595306 (IGF1)
   04115 p53 signaling pathway
    100595306 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100595306 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    100595306 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100595306 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    100595306 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    100595306 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100595306 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    100595306 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100595306 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    100595306 (IGF1)
   04213 Longevity regulating pathway - multiple species
    100595306 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100595306 (IGF1)
   05202 Transcriptional misregulation in cancer
    100595306 (IGF1)
   05205 Proteoglycans in cancer
    100595306 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    100595306 (IGF1)
   05218 Melanoma
    100595306 (IGF1)
   05215 Prostate cancer
    100595306 (IGF1)
   05224 Breast cancer
    100595306 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100595306 (IGF1)
   05414 Dilated cardiomyopathy
    100595306 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100595306 (IGF1)
   01522 Endocrine resistance
    100595306 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:nle04052]
    100595306 (IGF1)
Cytokines and neuropeptides [BR:nle04052]
 Cytokines
  Growth factors (RTK binding)
   100595306 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 100595306
NCBI-ProteinID: XP_003269978
Ensembl: ENSNLEG00000006394
UniProt: A0A2I3H886
LinkDB
Position
10:complement(69551562..69634294)
AA seq 153 aa
MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM
NT seq 462 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtgaagatgcacaccatgtcctcctcgcatctcttctacctggcgctgtgcctgctc
accttcaccagctctgccacagctggaccggagacgctctgcggggctgagctggtggat
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacagggtatggc
tccagcagtcggagggcacctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctgaggaggctggagatgtattgcgcacccctcaagcctgccaagtcagcccgctct
gtccgtgcccagcgccacaccgacatgcccaagacccagaaggaagtacatttgaagaac
gcaagtagagggagtgcaggaaacaagaactacagaatgtag

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