Nomascus leucogenys (northern white-cheeked gibbon): 100595901
Help
Entry
100595901 CDS
T03265
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04217
Necroptosis
nle04380
Osteoclast differentiation
nle04620
Toll-like receptor signaling pathway
nle04621
NOD-like receptor signaling pathway
nle04630
JAK-STAT signaling pathway
nle04658
Th1 and Th2 cell differentiation
nle04659
Th17 cell differentiation
nle05145
Toxoplasmosis
nle05160
Hepatitis C
nle05161
Hepatitis B
nle05162
Measles
nle05164
Influenza A
nle05165
Human papillomavirus infection
nle05167
Kaposi sarcoma-associated herpesvirus infection
nle05168
Herpes simplex virus 1 infection
nle05169
Epstein-Barr virus infection
nle05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100595901 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100595901 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100595901 (TYK2)
04621 NOD-like receptor signaling pathway
100595901 (TYK2)
04658 Th1 and Th2 cell differentiation
100595901 (TYK2)
04659 Th17 cell differentiation
100595901 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
100595901 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
100595901 (TYK2)
05160 Hepatitis C
100595901 (TYK2)
05171 Coronavirus disease - COVID-19
100595901 (TYK2)
05164 Influenza A
100595901 (TYK2)
05162 Measles
100595901 (TYK2)
05168 Herpes simplex virus 1 infection
100595901 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100595901 (TYK2)
05169 Epstein-Barr virus infection
100595901 (TYK2)
05165 Human papillomavirus infection
100595901 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100595901 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nle01001
]
100595901 (TYK2)
Enzymes [BR:
nle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100595901 (TYK2)
Protein kinases [BR:
nle01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100595901 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
100595901
NCBI-ProteinID:
XP_030676737
Ensembl:
ENSNLEG00000012193
LinkDB
All DBs
Position
10:60711171..60739365
Genome browser
AA seq
1202 aa
AA seq
DB search
MPAEPAARSMPLRHWGTARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSL
TAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRN
WHGMNPQEPAVYRCGPPGTEASSDHTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELS
SEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTR
LRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPC
YIRDSGEAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVQEEVNKEEVSKASSGSSGRNLQ
ASLSGKKAKAHKAVGQPADRPQEPLWAYFCDFRDITHVVLKERSVSIHRQDNKCLELSLP
SRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED
GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQNGAFVLEGWGRSFPSVRE
LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASTRTFNLSQLSFHRVDQKE
ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH
HDIALAFYETASLMSQVSHAHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM
AWKMMVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVSLGALS
REERVERIPWMAPECLPGGPNSLSTAMDKWGFGATLLEICFDGEAPLQSRNPSEKEHFYQ
RQHRLPEPSCPELATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADILTVNPDSL
ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRLGWK
QEIDILRTLYHEHIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQ
QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV
FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGVAQGQMTVLRLT
ELLERGERLPRPNKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS
VC
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgcctgctgagccagctgccaggagcatgcctctgcgccactgggggacggccaggggc
agcaaacctgttggggatggagcccagcccatggctgccatggggggcctgaaggtgctt
ctgcactgggctggtccaggcggtggggagccctgggtcactttcagtgagtcatcgctg
acagctgaggaagtctgcatccacattgcacataaagttggtatcactcctccttgtttc
aatctcttcgccctcttcgatgctcaagcccaagtctggttgcccccaaaccacatcctg
gagatccccagagacgcaagtctgatgctatatttccgcataaggttttatttccggaac
tggcatggcatgaatcctcaggaaccggctgtgtaccgttgtgggcccccaggaaccgag
gcatcctcagatcacacagcacaggggatgcaactcctggacccagcctcatttgagtac
ctctttgagcagggcaagcatgagtttgtgaatgacgtggcatcactgtgggagctgtcg
agcgaggaggagatccaccactttaagaatgagagcctgggcatggcctttctgcacctc
tgtcacctcgctctccgccatggcatccccctggaggaggtggccaagaagaccagcttc
aaggactgcatcccgcgctccttccgtcggcatatccgtcagcacagcgccctgacccgg
ctgcgccttcggaacgtcttccgcaggttcctgcgggacttccagccgggccgactctcc
cagcagatggtcatggtcaaatacctagccacactcgagcggctggcaccccgcttcggc
acagagcgtgtgcccgtgtgccacctgaggctgctggcccaggccgagggggagccctgc
tatatcagggacagtggggaggcccctacagaccctggccctgagtctgctgctgggccc
ccaacccacgaggtgctggtgacaggcactggtggcatccagtggtggccagtacaggag
gaggtgaacaaggaggaggtgagtaaggcttctagtggtagcagtggcaggaacctccaa
gccagcctgtctgggaagaaggccaaggctcacaaggcagttggccagccggcggacagg
ccgcaggagccactgtgggcctacttctgcgacttccgggacatcacccacgtggtgctg
aaagagcgcagtgtcagcatccaccggcaggacaacaagtgcctggagctgagtctgcct
tcccgggctgcggcgctgtccttcgtgtcgctggtggatggctatttccgcctgacggcc
gactccagccactacctgtgccatgaggtggctcccccacggctggtgatgagcatccgg
gatgggatccacggacctctgctggagccatttgtgcaggccaagctacggcccgaggac
ggcctgtacctcattcactggagcaccagccacccctaccgcctgatcctcacagtggcc
cagcgtagccaggcaccagacggcatgcagagcttgcggctccggaagttccccattgag
cagcagaacggggccttcgtgctggagggctggggccggtccttccccagcgttcgggaa
cttggggctgccttgcagggctgcttgctgagggccggggatgactgcttctctctgcgt
cgctgttgcctgccccaaccaggagaaacctccaatctcatcatcatgcggggggctcgg
gccagcaccaggacattcaacctcagccagctcagcttccaccgggttgaccagaaggag
atcacccagctgtcccacttgggccagggcacaaggaccaatgtgtatgagggccgcctg
cgagtggagggcagcggggaccctgaggagggcaagatggatgacgaggaccccctcgtg
cctggcagggaccgtgggcaggagctacgagtggtgctcaaagtgctggaccctagtcac
catgacattgccctggccttctacgagacagccagcctcatgagccaggtctcccacgcg
cacctggccttcgtgcatggcgtctgtgtgcgtggtcctgaaaatatcatggtgacagag
tacgtggagcacggacccctggatgtgtggttgcggagggagcggggccatgtgcccatg
gcttggaagatgatggtggcccagcagctggccagtgccctcagctacctggagaacaag
aaccttgttcatggtaatgtgtgtggccggaacatcctgctggcccggctggggctggca
gagggcaccagccccttcatcaagctgagtgatcccggcgtgagcctgggcgccctctcc
agggaggagcgggtggagaggatcccctggatggcccccgaatgcctaccaggtgggccc
aacagcctaagcactgccatggacaagtgggggtttggcgccaccctcctggagatctgc
tttgacggagaggcccctctgcagagccgcaacccctccgagaaggagcatttctaccag
aggcagcaccggctgcctgagccctcctgcccagagctggccacactcaccagccagtgt
ctgacctatgagccaacccagaggccatcattccgcaccatcctgcgtgacctcacccgg
ctgcagccccacactcttccagatcttgctgacatcttgactgtgaacccggactcactg
gcgtcagaccctacggttttccacaagcgctatttgaaaaagatccgagatctgggcgag
ggtcacttcggcaaggtcagcttgtactgctacgatccgaccaacgacggcactggcgag
atggtggcggtgaaagccctcaaggcagactgcggcccccagcaccgcttgggctggaag
caggagattgacattctgcgcacgctctatcacgagcacatcgtcaagtacaagggctgc
tgcgaggaccaaggcgagaagtcgctgcagctggtcatggagtacgtgcccctgggcagc
ctccgagactacctgccccggcacagcgtcgggctggcccagctgctgctcttcgcccag
cagatctgcgagggcatggcctatctgcacgcgcagcactacatccaccgagacctagcc
gcgcgcaacgtgcttctggacaacgacaggctggtcaagatcggggactttggcctagcc
aaagccgtgcccgaaggccacgagtactaccgcgtgcgcgaggatggggacagccccgtg
ttctggtatgccccagagtgcctgaaggagtataagttctactatgcgtccgatgtctgg
tcgttcggggtgaccctgtatgagctgctgacgcactgtgactccagccagagcccccct
acgaaattccttgagctcataggcgttgctcagggtcagatgacagttctgagactcacc
gagttgctggaacgaggggagaggctgccacggcccaacaaatgtccctgtgaggtctat
catctcatgaagaactgctgggagacagaggcgtccttccgcccaacctttgagaacctc
atacccatcctgaagacagtccatgagaagtaccaaggccaggctccttcagtgttcagc
gtgtgctga
DBGET
integrated database retrieval system
