KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100596183
Entry
100596183         CDS       T03265                                 
Symbol
TGFB2
Name
(RefSeq) transforming growth factor beta-2 proprotein isoform X1
  KO
K13376  transforming growth factor beta-2
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04060  Cytokine-cytokine receptor interaction
nle04068  FoxO signaling pathway
nle04110  Cell cycle
nle04218  Cellular senescence
nle04350  TGF-beta signaling pathway
nle04380  Osteoclast differentiation
nle04390  Hippo signaling pathway
nle04933  AGE-RAGE signaling pathway in diabetic complications
nle05140  Leishmaniasis
nle05142  Chagas disease
nle05144  Malaria
nle05145  Toxoplasmosis
nle05146  Amoebiasis
nle05152  Tuberculosis
nle05161  Hepatitis B
nle05166  Human T-cell leukemia virus 1 infection
nle05200  Pathways in cancer
nle05205  Proteoglycans in cancer
nle05206  MicroRNAs in cancer
nle05210  Colorectal cancer
nle05211  Renal cell carcinoma
nle05212  Pancreatic cancer
nle05220  Chronic myeloid leukemia
nle05225  Hepatocellular carcinoma
nle05226  Gastric cancer
nle05321  Inflammatory bowel disease
nle05323  Rheumatoid arthritis
nle05410  Hypertrophic cardiomyopathy
nle05414  Dilated cardiomyopathy
nle05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100596183 (TGFB2)
   04350 TGF-beta signaling pathway
    100596183 (TGFB2)
   04390 Hippo signaling pathway
    100596183 (TGFB2)
   04068 FoxO signaling pathway
    100596183 (TGFB2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100596183 (TGFB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100596183 (TGFB2)
   04218 Cellular senescence
    100596183 (TGFB2)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100596183 (TGFB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100596183 (TGFB2)
   05206 MicroRNAs in cancer
    100596183 (TGFB2)
   05205 Proteoglycans in cancer
    100596183 (TGFB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100596183 (TGFB2)
   05212 Pancreatic cancer
    100596183 (TGFB2)
   05225 Hepatocellular carcinoma
    100596183 (TGFB2)
   05226 Gastric cancer
    100596183 (TGFB2)
   05220 Chronic myeloid leukemia
    100596183 (TGFB2)
   05211 Renal cell carcinoma
    100596183 (TGFB2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100596183 (TGFB2)
   05161 Hepatitis B
    100596183 (TGFB2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100596183 (TGFB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100596183 (TGFB2)
   05144 Malaria
    100596183 (TGFB2)
   05145 Toxoplasmosis
    100596183 (TGFB2)
   05140 Leishmaniasis
    100596183 (TGFB2)
   05142 Chagas disease
    100596183 (TGFB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100596183 (TGFB2)
   05321 Inflammatory bowel disease
    100596183 (TGFB2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100596183 (TGFB2)
   05414 Dilated cardiomyopathy
    100596183 (TGFB2)
   05415 Diabetic cardiomyopathy
    100596183 (TGFB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100596183 (TGFB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:nle04052]
    100596183 (TGFB2)
   00536 Glycosaminoglycan binding proteins [BR:nle00536]
    100596183 (TGFB2)
Cytokines and neuropeptides [BR:nle04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   100596183 (TGFB2)
Glycosaminoglycan binding proteins [BR:nle00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100596183 (TGFB2)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta CBM96 SPEG_u2
Other DBs
NCBI-GeneID: 100596183
NCBI-ProteinID: XP_003265139
Ensembl: ENSNLEG00000014141
UniProt: A0A2I3GW08
LinkDB
Position
5:complement(28752719..28859136)
AA seq 414 aa
MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEP
EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPP
TFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSP
TQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIP
NKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRK
KRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQH
SRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS
NT seq 1245 nt   +upstreamnt  +downstreamnt
atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggtcgcgctcagc
ctgtctacctgcagcacactcgatatggaccagttcatgcgcaagaggatcgaggcgatc
cgcgggcagatcctgagcaagctgaagctcaccagtcccccagaagactatcctgagccc
gaggaagtccccccggaggtgatttccatctacaacagcaccagggacttgctccaggag
aaggcgagccggagggcggccgcctgcgagcgcgagagaagcgacgaagagtactacgcc
aaggaggtttacaaaatagacatgccgcccttcttcccctccgaaaatgccatcccgccc
actttctacagaccctacttcagaattgttcgatttgacgtctcagcaatggagaagaat
gcttccaatttggtgaaagcagagttcagagtctttcgtttgcagaacccaaaagccaga
gtgcctgaacaacggattgagctgtatcagattctcaagtccaaagatttaacatctcca
acccagcgctacatcgacagcaaagttgtgaaaacaagagcagaaggcgaatggctctcc
ttcgatgtaactgatgctgttcatgaatggcttcaccataaagacaggaacctgggattt
aaaataagcttacactgtccctgctgcacttttgtaccatctaataattacatcatccca
aataaaagcgaagaactagaagcaagatttgcaggtattgatggcacctccacatatacc
agtggtgatcagaaaactataaagtccactaggaaaaaaaacagtgggaagaccccacat
ctcctgctaatgttattgccctcctacagacttgagtcacaacagaccaaccggcggaag
aagcgtgctttggatgcagcctattgctttagaaatgtgcaggataattgctgcctacgt
ccactttacattgatttcaagagggatctagggtggaaatggatacacgaacccaaaggg
tacaatgccaacttctgtgctggagcgtgcccgtatttatggagttcagacactcagcac
agcagggtcctgagcttatataataccataaatccagaagcatctgcttctccttgctgc
gtgtcccaagatttagaacctctaaccattctctactacattggcaaaacacccaagatt
gaacagctttctaatatgattgtaaagtcttgcaaatgcagctaa

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