Nomascus leucogenys (northern white-cheeked gibbon): 100596241
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Entry
100596241 CDS
T03265
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100596241 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
nle03032
]
100596241 (TOP2B)
03036 Chromosome and associated proteins [BR:
nle03036
]
100596241 (TOP2B)
Enzymes [BR:
nle01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100596241 (TOP2B)
DNA replication proteins [BR:
nle03032
]
Eukaryotic type
DNA Topoisomerases
100596241 (TOP2B)
Chromosome and associated proteins [BR:
nle03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100596241 (TOP2B)
Centrosome formation proteins
Centriole proteins
100596241 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
100596241
NCBI-ProteinID:
XP_003256818
Ensembl:
ENSNLEG00000003693
UniProt:
A0A2I3H296
LinkDB
All DBs
Position
4:125667931..125736061
Genome browser
AA seq
1621 aa
AA seq
DB search
MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL
LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC
IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG
YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS
KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV
ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK
NKAGVSVKPFQVKNHIWIFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN
CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS
AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD
AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK
QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE
DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI
LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL
MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDN
LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD
PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML
NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD
HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT
IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY
ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERE
DILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL
DTATVKVEFDEEFSGAPVEGAGEEASTPSAPINKGPKPRREKKEPGTRVRKTPTSSGKPS
AKKMKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD
DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG
NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTAP
KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS
KTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEEDVDFAMF
N
NT seq
4866 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggctgcggcgcgggagccggcgtgggcggcggcaacggggcactg
acctgggtgaacaatgctgcaaaaaaagaagagtcagaaactgccaacaaaaatgattct
tcaaagaagttgtctgttgagagagtgtatcagaagaagacacaacttgaacacattctt
cttcgtcctgatacatatattgggtcagtggagccattgacgcagttcatgtgggtatat
gatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaagatc
tttgatgaaattttggttaatgctgctgacaataaacagagggataagaacatgacttgt
attaaagtttctattgatcctgaatctaacattataagcatttggaataatgggaaaggc
attccagtagtagaacacaaggtagagaaagtttatgttcctgctttaatttttggacag
cttttaacatccagtaactatgatgatgatgagaaaaaagttacaggtggtcgtaatggt
tatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaacagcttgcaaa
gaatacaaacacagttttaagcagacatggatgaataatatgatgaagacttctgaagcc
aaaattaaacattttgatggtgaagattacacatgcataacattccaaccagatctgtcc
aaatttaagatggaaaaacttgacaaggatattgtggccctcatgactagaagggcatat
gatttggctggttcatgtagaggggtcaaggtcatgtttaatggaaagaaattgcctgta
aatggatttcgtagttacgtagatctttatgtgaaagacaaattggatgaaactggggtg
gccctgaaagttattcatgagcttgcaaatgaaagatgggatgtttgtctcacattgagt
gaaaaaggattccagcaaatcagctttgtaaatagtattgcaactacaaaaggtggacgg
cacgtggattatgtggtagatcaagttgttggtaaactgattgaagtagttaagaaaaag
aacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatatatggatttttatt
aattgccttatcgaaaatccaacttttgattctcagactaaggaaaacatgaccctgcag
cccaaaagttttgggtctaaatgccagctgtcagaaaaattttttaaagcagcctctaat
tgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagactcagctgaat
aagaagtgttcatcagtaaaatacagtaaaatcaaaggtattcccaaactggatgacgct
aatgatgctggtggtaaacattccctggagtgtacactgatattaacagagggagactct
gccaaatcactggctgtgtctggattaggtgtgattggacgagacagatacggagttttt
ccactcaggggcaaaattcttaatgtacgggaagcttctcataaacagatcatggaaaat
gctgaaataaataatattattaaaatagttggtctacaatataagaaaagttatgatgat
gcagaatctctgaaaactttacgctatggaaagattatgattatgactgatcaggatcaa
gatggttctcacataaaaggcctgcttattaatttcatccatcacaattggccatcactt
ttgaagcatggttttctcgaagagttcattactcctattgtaaaggcaagcaaaaataag
caggaactttccttctacagtattcctgaatttgatgaatggaaaaaacatatagaaaac
cagaaagcctggaaaataaagtactataaaggattgggtactagtacagctaaagaagca
aaggaatattttgctgatatggaaaggcatcgcatcttgtttagatatgctggtcctgaa
gatgatgctgccattaccttggcatttagtaagaagaagattgatgacagaaaagaatgg
ttaacaaattttatggaagaccggagacagcgtaggctacatggcttaccagagcaattt
ttatatggtactgcaacaaagcatttgacttataatgatttcatcaacaaggaattgatt
ctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggctttaaacct
ggccagcggaaagttttatttacctgtttcaagaggaatgataaacgtgaagtaaaagtt
gcccagttggctggatctgttgctgagatgtcggcttatcatcatggagaacaagcattg
atgatgactattgtgaatttggctcagaactttgtgggaagtaacaacattaacttgctt
cagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagcccccgt
tatattttcacaatgttaagctctttagcaaggctactttttcctgctgtggatgacaac
ctccttaagttcctttatgatgataatcaacgtgtagagcctgagtggtatatacctata
attcccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaacta
cccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcctggat
cctcatcccatgcttccaaactacaaaaactttaaaggcacgattcaagaacttggtcaa
aaccagtatgcagtcagtggtgaaatatttgtagtggacagaaacacagtagaaattaca
gagcttccagttagaacatggacacaggtatataaagaacaggttttagaacctatgcta
aatgggacagacaaaacaccagcattaatttctgattataaagaatatcatactgacaca
actgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagctgctgga
ctgcataaagtttttaaacttcaaactactcttacttgtaattccatggtactctttgat
catatgggatgtctgaagaaatatgaaactgtgcaagacattctgaaagaattctttgat
ttacgattaagttattacggtttacgtaaggagtggcttgtgggaatgttgggagcagaa
tctacaaagcttaacaatcaagcccgtttcattttagagaagatacaagggaaaattact
atagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatct
gacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggatgaaacacaa
aaccagcatgatgatagttcctccgattcaggaactccttcaggcccagattttaattat
attttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgattaaacag
agagatgcaaaagggcgagaagtcaatgatcttaaaagaaaatctccttcagatctttgg
aaagaagatttagcagcctttgttgaagaactggataaagtggaatctcaagaacgagaa
gatattctggctggaatgtctggaaaagcaattaaaggtaaagttggcaaacctaaggtg
aagaaactccaattggaagagacaatgccctcaccttatggcagaagaataattcctgaa
attacagctatgaaggcagatgccagcaaaaagttgctgaagaagaagaagggtgatctt
gatactgcaacagtgaaagtggaatttgatgaagaattcagtggagcgccagtagaaggt
gcaggagaagaggcgtcgactccgtcagctcctataaataaaggccccaaacccagaagg
gagaagaaggagcctggtaccagagtgagaaaaacacctacatcatctggtaaacctagt
gcaaagaaaatgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagtgat
ttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagcagcagcc
gaaagacctaaatacacatttgatttctcagaagaagaggatgatgatgctgatgatgat
gatgatgacaataatgatttagaggaattgaaagttaaagcatctcccataacaaatgat
ggggaagatgaatttgttccttcagatgggttagataaagatgaatatacattttcacca
ggcaaatcaaaagccactccagaaaaatctttgcatgacaaaaaaagtcaggattttgga
aatctcttctcctttccttcatattctcagaagtcagaagatgattcagctaaatttgac
agtaatgaagaagattctgcttctgttttttcaccatcatttggtctgaaacagacagat
aaagttccaagtaaaaccgtagctgctaaaaagggaaaaccgtcttcagatacagcccct
aagcccaagagagccccaaaacagaagaaagtagtagaggctgtaaactctgactcggat
tcagaatttggtattccaaagaagactacaacaccaaaaggtaaaggccgaggggcaaag
aaaaggaaagcatctggctctgaaaatgaaggcgattataaccctggcaggaaaacatcc
aaaacaacaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggacatc
ttcccctcagacttccctactgagccaccttctctgccacgaaccggtcgggctaggaaa
gaagtaaaatattttgcagagtctgatgaagaagaagaagacgttgattttgcaatgttt
aattaa
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integrated database retrieval system
