Nomascus leucogenys (northern white-cheeked gibbon): 100597073
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Entry
100597073 CDS
T03265
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04020
Calcium signaling pathway
nle04022
cGMP-PKG signaling pathway
nle04024
cAMP signaling pathway
nle04148
Efferocytosis
nle04260
Cardiac muscle contraction
nle04261
Adrenergic signaling in cardiomyocytes
nle04380
Osteoclast differentiation
nle04919
Thyroid hormone signaling pathway
nle04972
Pancreatic secretion
nle05010
Alzheimer disease
nle05017
Spinocerebellar ataxia
nle05022
Pathways of neurodegeneration - multiple diseases
nle05410
Hypertrophic cardiomyopathy
nle05412
Arrhythmogenic right ventricular cardiomyopathy
nle05414
Dilated cardiomyopathy
nle05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100597073 (ATP2A2)
04024 cAMP signaling pathway
100597073 (ATP2A2)
04022 cGMP-PKG signaling pathway
100597073 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100597073 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100597073 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
100597073 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
100597073 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
100597073 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
100597073 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100597073 (ATP2A2)
05017 Spinocerebellar ataxia
100597073 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
100597073 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100597073 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
100597073 (ATP2A2)
05414 Dilated cardiomyopathy
100597073 (ATP2A2)
05415 Diabetic cardiomyopathy
100597073 (ATP2A2)
Enzymes [BR:
nle01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100597073 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
100597073
NCBI-ProteinID:
XP_012365368
Ensembl:
ENSNLEG00000002636
UniProt:
A0A2I3HQE6
LinkDB
All DBs
Position
10:77390200..77462881
Genome browser
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagactgtggaggaggtgctgggccacttcggcgtcaacgag
agtaccgggctgagcctggagcaggtcaagaagcttaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagacttg
ctagttaggattttattactggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccttttgtaattttactcatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgccatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataaggttaacttccatcaaatctaccacactaagagttgaccagtcaattctc
acaggtgaatctgtctctgtcatcaagcacactgatcccgtccctgacccacgagctgtc
aaccaagataaaaagaacatgctgttttctggtacaaacattgctgctgggaaagctatg
ggagtggtggtagcaactggagttaacactgaaattggcaagatccgggatgaaatggtg
gcaacagaacaggagagaacacccctccagcaaaaactagatgaatttggggaacagctt
tccaaagtcatctcccttatttgcattgcagtctggatcataaatattgggcacttcaat
gacccggttcatggagggtcctggatcagaggtgctatttactactttaaaattgcagtg
gccctggctgtagcagccattcctgaaggtctgcctgcagtcattaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagcctcccgtctgtggaa
acccttggttgtacttctgttatctgctcggacaagactggtacacttacaacaaaccag
atgtcagtctgcaggatgttcattctggacagagtggaaggtgatacttgttcccttaat
gagtttaccataactggatcaacttacgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcaccagtatgatggtctggtagaattagcaacaatttgtgctctttgt
aatgactctgctttggattacaatgaggcaaagggtgtatatgaaaaagttggagaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagaacgtgcaaatgcctgcaactcagtcattaaacagctgatgaaa
aaggaattcactctagagttttcacgtgacagaaagtcaatgtcggtttactgtacacca
aataaaccaagcaggacatcaatgagcaagatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagtactaaggttcctatgacctctggagtc
aaacagaagatcatgtctgtcattcgagagtggggtagtggcagcgacacactgcgatgc
ctggccctggccactcacgacaacccactgagaagagaagaaatgcaccttgaggactct
gccaactttattaaatatgagaccaatctgaccttcgttggctgcgtgggcatgctggat
cctccaagaatcgaggtggcctcctccgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcactggggacaacaagggcactgctgtggccatctgtcgccgcattggcatc
ttcgggcaggatgaggacgtgacgtcgaaagctttcacaggccgggagtttgatgaactc
aacccctccgcccagcgagacgcctgcctgaacgcccgctgttttgcgcgagttgaaccc
tcccacaagtctaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggcgatggcgtgaacgatgctcctgctctgaagaaagccgagattggcattgctatgggc
tctgggactgcagtggctaaaaccgcctctgagatggtcctggcggatgacaacttctcc
accattgtggctgccgttgaggaggggcgggcaatctacaacaacatgaaacagttcatc
cgctacctcatctcatccaacgtcggggaagttgtctgtattttcctgacagcagccctt
ggatttcccgaggctttgattcctgttcagctgctctgggtcaatctggtgacagatggc
ctgcctgccactgcactggggttcaaccctcctgatctggacatcatgaataaacctccc
cggaacccaaaggaaccattgatcagcgggtggctctttttccgttacttggctattggc
tgttacgtcggtgctgctaccgtgggtgctgctgcatggtggttcattgctgctgacggt
ggtccaagagtgtccttctaccagctgagtcatttcctacagtgtaaagaggacaacccg
gactttgaaggcgtggattgtgcaatctttgaatccccatacccgatgacaatggcgctc
tctgttctagtaactatagaaatgtgtaacgccctcaacagcttgtccgaaaaccagtcc
ttgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcactccacttcctgatcctctatgtcgaacccttgccactcatcttccagatcacaccg
ctgaacgtgacccagtggctgatggtgctgaaaatctccttgcccgtgattctcatggac
gagacgctcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcctctggtgatctgggtctatagcacagacactaactttagcgatatgttc
tggtcttga
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