Nomascus leucogenys (northern white-cheeked gibbon): 100597430
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Entry
100597430 CDS
T03265
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00790
Folate biosynthesis
nle01100
Metabolic pathways
nle01240
Biosynthesis of cofactors
nle01523
Antifolate resistance
nle04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100597430 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100597430 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100597430 (FPGS)
Enzymes [BR:
nle01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
100597430 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
100597430
NCBI-ProteinID:
XP_030673729
Ensembl:
ENSNLEG00000017495
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Position
8:103938602..103968966
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AA seq
672 aa
AA seq
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MSRARSHLRAALLLAAASARGVTTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMERYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKVPHAGGLAGGCGW
GCYMFQLPISPEEGLHGLWALTSPCATGWQLCLHAPLLPLPDTHGLPRLPPREGVCPLPR
TLHLRPWEQEPQQAWGLPASMWPLGTLISPAMPSGLWQVDLAVVEVGIGGAYDCTNIIRK
PVVCGVSSLGIDHTSLLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISC
PLYLCPTLEALEEGGPPLTLGLEGEHQRSNAALALQLAHCWLQRQDPHGAGEPKASRPGL
LWQLPLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSVQACVRWFRQA
LQGRERPSGGPEVRVLLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQN
FTVTLDQVLLRCLEHQQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSL
VFSCISHALQWISQGRDPIFQPPSPPKGLLTHAVAHSGASILREAAAIHVLVTGSLHLVG
GVLKLLEPALSQ
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggagccacctgcgcgccgctctattactggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcggcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgctgtgcgcatgctcaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccagacacagctggaagccatggaa
cggtacctggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccac
gtcactgggacgaaggggaagggctccacctgtgccttcacggaatgtatcctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcctgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggtgccccatgcaggagggctggcgggtgggtgtggttgg
gggtgctacatgttccagctccccatctccccagaagaggggctgcacgggctctgggcc
ttgacatctccctgtgccacaggatggcagctgtgtctccatgcccccctacttccgctt
cctgacactcatggccttccacgtcttcctccaagagaaggtgtgtgccctctccctaga
accctgcatctgaggccttgggaacaggaacctcagcaggcctgggggctccctgcttcc
atgtggcctctgggcaccctcatatcccctgccatgccctctggtctttggcaggtggac
ctggcagtggtggaggtgggcattggcggggcttatgactgcaccaacatcatcaggaag
cctgtggtgtgcggagtctcctctcttggcatcgaccacaccagcctcctgggggatacg
gtggagaagatcgcatggcagaaagggggcatctttaagcaaggtgtccctgccttcact
gtactccaacctgaaggtcccctggcagtgctgagggaccgagcccagcagatctcatgt
cctctatacctgtgtccgacgctggaggccctggaggaaggggggccgccgctgaccctg
ggcctggagggggagcaccagcggtccaacgccgccttggccttgcagctggcccactgc
tggctgcagcggcaggacccccatggtgctggggagccgaaggcatccaggccagggctc
ctgtggcagctgcccctggcacccgtgttccagcccacatcccacatgcggcttgggctt
cgtaacacggagtggccgggccggacgcaggtgctgcggcgcgggcccctcacctggtac
ctggacggggcgcacaccgccagcagcgtgcaggcctgcgtgcgctggttccgccaagcg
ctgcagggccgcgagaggccgagcggtggcccagaggttcgagtcttgctcttcaatgct
accggggaccgggacccggcggccctgctgaagctgctgcagccctgccagtttgactat
gccgtcttctgccctaacctgacagaggtgtcatccacaggcaacgcagaccaacagaac
ttcacggtgacactggaccaggttctgctccgctgcctggaacaccagcagcactggaac
cacctggacgaagagcaggccagcccggacctctggagtgcccccagcccagagcctggt
gggtctgcatccctgcttctggcgccccacccaccccacacctgcagtgccagttccctc
gtcttcagctgcatttcacatgccttgcaatggatcagccaaggccgagaccccatcttc
cagccacccagtcccccaaagggcctcctcacccacgccgtggctcacagtggggccagc
atactccgtgaggctgctgccatccatgtgctagtcactggcagcctgcacctggtgggt
ggtgtcctgaagcttctggagcccgcactgtcccagtag
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