KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100598029
Entry
100598029         CDS       T03265                                 
Symbol
PPP3CC
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04020  Calcium signaling pathway
nle04022  cGMP-PKG signaling pathway
nle04114  Oocyte meiosis
nle04218  Cellular senescence
nle04310  Wnt signaling pathway
nle04360  Axon guidance
nle04370  VEGF signaling pathway
nle04380  Osteoclast differentiation
nle04625  C-type lectin receptor signaling pathway
nle04650  Natural killer cell mediated cytotoxicity
nle04658  Th1 and Th2 cell differentiation
nle04659  Th17 cell differentiation
nle04660  T cell receptor signaling pathway
nle04662  B cell receptor signaling pathway
nle04720  Long-term potentiation
nle04724  Glutamatergic synapse
nle04728  Dopaminergic synapse
nle04921  Oxytocin signaling pathway
nle04922  Glucagon signaling pathway
nle04924  Renin secretion
nle05010  Alzheimer disease
nle05014  Amyotrophic lateral sclerosis
nle05020  Prion disease
nle05022  Pathways of neurodegeneration - multiple diseases
nle05031  Amphetamine addiction
nle05152  Tuberculosis
nle05163  Human cytomegalovirus infection
nle05166  Human T-cell leukemia virus 1 infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05170  Human immunodeficiency virus 1 infection
nle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nle05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100598029 (PPP3CC)
   04310 Wnt signaling pathway
    100598029 (PPP3CC)
   04370 VEGF signaling pathway
    100598029 (PPP3CC)
   04020 Calcium signaling pathway
    100598029 (PPP3CC)
   04022 cGMP-PKG signaling pathway
    100598029 (PPP3CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100598029 (PPP3CC)
   04218 Cellular senescence
    100598029 (PPP3CC)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100598029 (PPP3CC)
   04650 Natural killer cell mediated cytotoxicity
    100598029 (PPP3CC)
   04660 T cell receptor signaling pathway
    100598029 (PPP3CC)
   04658 Th1 and Th2 cell differentiation
    100598029 (PPP3CC)
   04659 Th17 cell differentiation
    100598029 (PPP3CC)
   04662 B cell receptor signaling pathway
    100598029 (PPP3CC)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100598029 (PPP3CC)
   04921 Oxytocin signaling pathway
    100598029 (PPP3CC)
   04924 Renin secretion
    100598029 (PPP3CC)
  09156 Nervous system
   04724 Glutamatergic synapse
    100598029 (PPP3CC)
   04728 Dopaminergic synapse
    100598029 (PPP3CC)
   04720 Long-term potentiation
    100598029 (PPP3CC)
  09158 Development and regeneration
   04360 Axon guidance
    100598029 (PPP3CC)
   04380 Osteoclast differentiation
    100598029 (PPP3CC)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100598029 (PPP3CC)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100598029 (PPP3CC)
   05170 Human immunodeficiency virus 1 infection
    100598029 (PPP3CC)
   05163 Human cytomegalovirus infection
    100598029 (PPP3CC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100598029 (PPP3CC)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100598029 (PPP3CC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100598029 (PPP3CC)
   05014 Amyotrophic lateral sclerosis
    100598029 (PPP3CC)
   05020 Prion disease
    100598029 (PPP3CC)
   05022 Pathways of neurodegeneration - multiple diseases
    100598029 (PPP3CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    100598029 (PPP3CC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100598029 (PPP3CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nle01009]
    100598029 (PPP3CC)
Enzymes [BR:nle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100598029 (PPP3CC)
Protein phosphatases and associated proteins [BR:nle01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100598029 (PPP3CC)
SSDB
Motif
Pfam: Metallophos DUF5378 DUF7084
Other DBs
NCBI-GeneID: 100598029
NCBI-ProteinID: XP_030672812
Ensembl: ENSNLEG00000015570
UniProt: M3ZAP8
LinkDB
Position
8:27438104..27546407
AA seq 511 aa
MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKI
INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDC
LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFMEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGL
TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR
KDSIHADGPTKSVTSAHSHAAHRSNQGKKAQ
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgtccgggaggcgcttccacctctccaccaccgaccgcgtcatcaaagctgtccccttt
cctccaacccaacggcttacttttaaggaagtatttgagaatgggaaacctaaagttgat
gttttaaaaaaccatttggtaaaggaaggacgactggaagaggaagtagccttaaagata
atcaatgatggggctgccatcctgaggcaagagaagactatgatagaagtagatgctcca
atcacagtatgtggtgatattcacggacaattctttgacctaatgaagttatttgaagtt
ggaggatcacctagtaacacacgctacctctttctgggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtatttatggagtttaaagattaatcatcccaaaacattg
tttctgcttcggggaaatcatgaatgcaggcatcttacagactatttcaccttcaaacag
gaatgtcgaatcaaatattcggaacaggtatatgatgcctgtatggagacatttgactgt
cttcctcttgctgccctcttaaaccagcagtttctctgtgtacatggaggaatgtcacct
gaaattacttctttagatgacattaggaaattagacaggtttatggaacctcccgccttt
ggacctgtgtgtgacctgctttggtctgatccctcagaggattatggcaatgagaagacc
ttggagcactatacccacaacactgtccgagggtgctcttatttctacagttaccctgca
gtttgtgaatttttgcagaacaataatttactatcaattatcagagcccatgaagcccaa
gatgctggatatcgaatgtacaggaagagtcaagcaacaggctttccatcacttattaca
attttctctgcccccaattacctagatgtctataacaataaagctgctgtgttgaaatac
gaaaacaatgtcatgaatatcaggcagtttaactgttctccacatccctactggcttcca
aactttatggatgttttcacatggtctttgccttttgttggggaaaaagtcacagagatg
ctggtaaatgtgctcaacatatgctctgatgacgaactgatttctgatgatgaagcagaa
ggaagcactacagttcgtaaggagatcatcaggaataagatcagagccattgggaagatg
gcacgggtcttttcaattcttcggcaagaaagtgagagtgtgctgactctcaagggcctg
actcccacaggcacgctccctctgggcgtcctctcaggaggcaagcagactatcgagaca
gccacagtagaagcggtagaggcccgggaagccatcagagggttctcgcttcagcacaag
atccggagttttgaagaagcgcgaggtctggaccgaattaatgagcgaatgccaccccga
aaggatagcatacacgctgatgggccaacgaaatccgtaacctcagcacactcacatgct
gcacacaggagcaaccaagggaagaaagcccagtaa

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