Nomascus leucogenys (northern white-cheeked gibbon): 100599238
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Entry
100599238 CDS
T03265
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle03060
Protein export
nle04141
Protein processing in endoplasmic reticulum
nle04612
Antigen processing and presentation
nle04918
Thyroid hormone synthesis
nle05012
Parkinson disease
nle05014
Amyotrophic lateral sclerosis
nle05020
Prion disease
nle05022
Pathways of neurodegeneration - multiple diseases
nle05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
100599238 (HSPA5)
04141 Protein processing in endoplasmic reticulum
100599238 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
100599238 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
100599238 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
100599238 (HSPA5)
05014 Amyotrophic lateral sclerosis
100599238 (HSPA5)
05020 Prion disease
100599238 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
100599238 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100599238 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
nle03110
]
100599238 (HSPA5)
04131 Membrane trafficking [BR:
nle04131
]
100599238 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
nle04147
]
100599238 (HSPA5)
Enzymes [BR:
nle01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
100599238 (HSPA5)
Chaperones and folding catalysts [BR:
nle03110
]
Heat shock proteins
HSP70 / DNAK
100599238 (HSPA5)
Membrane trafficking [BR:
nle04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
100599238 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
100599238 (HSPA5)
Exosome [BR:
nle04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
100599238 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
100599238 (HSPA5)
Exosomal proteins of colorectal cancer cells
100599238 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
100599238
NCBI-ProteinID:
XP_003264177
Ensembl:
ENSNLEG00000017348
UniProt:
G1S6C2
LinkDB
All DBs
Position
8:complement(101366582..101371839)
Genome browser
AA seq
654 aa
AA seq
DB search
MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccctggtggccgcgatgctgctgctgctcagcgcggcgcgggccgaggag
gaggacaagaaagaggacgtgggcacggtggtcggcatcgacctggggaccacctactcc
tgcgtcggcgtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc
atcacgccgtcctatgtggccttcactcctgaaggggaacgtctgattggcgatgccgcc
aagaaccagctcacctccaaccccgagaacacggtctttgacgccaagcggctcatcggc
cgcacgtggaatgacccgtctgtgcagcaggacatcaagttcttgccgttcaaggtggtt
gaaaagaaaactaaaccatacattcaagttgatattggaggtgggcaaacaaagacattt
gctcctgaagaaatttctgccatggttctcactaaaatgaaagaaaccgctgaggcttat
ttgggaaagaaggttacccatgcagttgttactgtacccgcctattttaatgatgcccaa
cgccaagcaaccaaagacgctggaactattgctggcctaaatgttatgaggatcatcaat
gagcctacggcagctgctattgcttatggcctggataagagggagggggagaagaacatc
ctggtgtttgacctgggtggcggaaccttcgatgtgtctcttctcaccattgataatggt
gtcttcgaagtcgtggccactaatggagatactcatctgggtggagaagactttgaccag
cgtgtcatggaacacttcatcaaactgtacaaaaagaagactggcaaagacgtcaggaaa
gacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttttctgag
accctgactcgggccaaatttgaagagctcaacatggatctgttccggtctactatgaag
cccgtccagaaagtgttggaagattctgatttgaagaagtctgatattgatgaaattgtt
cttgttggtggctcgactcgaattccaaagattcagcaactggttaaagaattcttcaat
ggcaaggaaccatcccgtggcataaacccagatgaagctgtagcatatggtgctgctgtc
caggctggtgtgctctctggtgatcaagatacaggtgacctggtactgcttgatgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
acagtggtgcctaccaagaagtctcagatcttttctacagcttccgataatcaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctgacaaaagacaatcatcttctcggt
acatttgatctgactggcattcctcctgctcctcgtggggtcccacagattgaagtcacc
tttgagatagatgtgaatggtattcttcgagtgacagctgaagacaaaggtacggggaac
aaaaataagatcacaattaccaatgaccagaatcgcctgacaccggaagaaatcgaaagg
atggttaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcattgat
agtagaaatgagttggaaagctatgcctattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactttcctctgaagataaggagaccatggaaaaagctgtagaagaa
aagattgaatggctggaaagccaccaagatgctgacattgaagacttcaaagctaagaag
aaggaactggaagaaattgttcaaccaattatcagcaaactctatggaagtgcaggccct
cctccaactggtgaagaggatacagcagaaaaagatgagttgtag
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