| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
nle Nomascus leucogenys (northern white-cheeked gibbon)
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| Pathway |
| nle04977 | Vitamin digestion and absorption |
| nle04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:nle00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100602390 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
100602390 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
100602390 (ABCC1)
04981 Folate transport and metabolism
100602390 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100602390 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100602390 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:nle02000]
100602390 (ABCC1)
Enzymes [BR:nle01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
100602390 (ABCC1)
Transporters [BR:nle02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
100602390 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
18:complement(87403561..87553576)
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| AA seq |
1475 aa
MTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQL
ERRKGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAQVDLFRDITFYIYFSLLLIQL
VLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNK
EDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQ
KEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPNWQGYFY
TVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNL
MSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVFAGVAVMVLMVPVNAVMAMK
TKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLS
AVGTFTWVCTPFLVALCTFAVYVTIDKNNILDAQTAFVSLALFNILRFPLNILPMVISSI
VQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARGDPPTLNGITF
SIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLQENI
LFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNA
DVYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKI
SEMGSYQELLARDGAFAEFLRTYASTEQEQDPEENGSKVMDEEEAGVTGVSGPGKEAKQM
ENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHSSTAELQKAGAKKEETWKLVEADKAQTG
QVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRL
SVYGALGISQGIAVFGYSMAVSIGGILASRFLHVDLLHSILRSPMSFFERTPSGNLVNRF
SKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVAS
SRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVAN
RWLAVRLECVGNCIVLCAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMET
NIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVT
INGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQD
PVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLEHECAEGGENLSVGQRQ
LVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTR
VIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
4428 nt +upstreamnt +downstreamnt
atgacacctctcaacaaaaccaaaactgccttgggatttttgctgtggatcgtctgctgg
gcagacctcttctactctttctgggaaagaagtcggggcatattcctggccccagtgttt
ctggtcagcccaactctcttgggcatcaccatgctgcttgctacctttttaattcagctg
gagaggaggaagggagttcagtcttcagggatcatgctcactttctggctgatagcccta
ctgtgtgcgctagccatcctgagatccaaaattatgactgccttaaaagaggatgcccag
gtggacctgtttcgtgacatcactttctacatctacttttccctgttactcattcagctc
gtcttgtcctgtttctcagatcgttcacccctgttctcggaaaccatccatgaccctaat
ccctgcccagagtccagcgcctccttcctgtccaggatcaccttctggtggatcacaggg
ttgattgtccggggctaccgccagcccctggagggcagcgacctctggtccttaaacaag
gaggacacgtcggaacaagtcgtgcctgttttggtaaagaactggaagaaggaatgtgcc
aagactaggaagcagccagtgaaggttgtgtactcctccaaggatcctgcccagccgaaa
gagagttccaaggtggatgcgaatgaggaggtggaggctttgattgtcaagtccccacag
aaggagtggaacccctccctgtttaaggtgttatacaagacctttgggccctacttcctc
atgagcttcttctttaaggccatccacgacctgatgatgttttccgggccgcagatctta
aagttgctcatcaagttcgtgaacgacacgaaggcccctaattggcagggctacttctac
accgtactgctgttcgtcactgcctgcctgcagaccctcgtgctgcaccagtacttccac
atctgtttcgtcagtggcatgaggatcaagaccgctgtcattggggctgtctatcggaag
gccctggtgatcaccaattcagccagaaaatcctccacggtcggggagatcgtcaacctc
atgtctgtggacgctcagaggttcatggacttggccacgtacattaacatgatctggtca
gcccccctgcaagtcatccttgctctctacctcctgtggctgaacctgggcccttccgtc
ttcgctggagtggcggtgatggtcctcatggtgcccgtcaatgctgtgatggcgatgaag
accaagacgtatcaggtggcccacatgaagagcaaagacaatcggatcaagctgatgaac
gaaattctcaatgggatcaaagtgctaaagctttatgcctgggagctggcattcaaggac
aaggtcctggccatcaggcaggaggagctgaaggtgctgaagaagtctgcctacctgtca
gcggtgggcaccttcacctgggtctgcacgcccttcctggtggccctgtgcacatttgcc
gtctacgtgaccattgacaagaacaacatcctggatgcccagacagccttcgtgtctttg
gccttgttcaacatcctccggtttcccctgaacattctccccatggtcatcagcagcatc
gtgcaggcgagtgtctccctcaaacgcctgaggatctttctctcccatgaggagctggaa
cctgacagcatcgagcgacggcctgtcaaagacggcgggggcacgaacagcatcaccgtg
aggaatgccacattcacctgggccaggggcgaccctcccacgctgaatggcatcaccttc
tccatcccggaaggtgccttggtggccgtggtgggccaggtgggctgcggaaagtcgtcc
ctgctctcagccctcttggctgagatggacaaagtggaggggcacgtggctatcaagggc
tccgtggcctatgtgccacagcaggcctggattcagaatgattctctccaagaaaacatc
ctttttggatgtcagctggaggaaccatattacaggtccgtgatacaggcctgtgccctc
ctcccagacctggaaatcctgcccagcggggatcggacagagattggcgagaagggcgtg
aacctgtctgggggccagaagcagcgcgtgagcctggcccgggccgtgtactgcaacgct
gacgtttacctcttcgatgatcccctctcagcagtggatgcccacgtgggaaaacacatc
tttgaaaatgtgattggccccaaggggatgctgaagaacaagacgcggatcttggtcact
cacagcatgagctacttgccgcaggtggacgtcatcatcgtcatgagtggcggcaagatc
tctgagatgggttcctaccaggagctgctggcccgagacggcgccttcgctgagttcctg
cgtacctacgccagcacagagcaggagcaggacccagaggagaacggcagcaaagtgatg
gacgaggaggaagcaggggtcacgggcgtcagcggtccagggaaggaagcaaagcaaatg
gagaatggcatgctggtgacggacagtgcagggaagcaactgcagagacagctcagcagc
tcctcctcctatagcggggacatcagcaggcaccacagcagcaccgcagaactgcagaaa
gctggggccaagaaggaggagacctggaagctggtggaggctgacaaggcgcagacgggg
caggtcaagctttccgtatactgggactacatgaaggccatcggactcttcatctccttt
ctcagcatcttccttttcatgtgtaaccacgtgtccgcgctggcttccaactattggctc
agtctctggactgatgaccccatcgtcaacgggacccaggagcacactaaagtccggctg
agcgtctatggagccctgggcatttcacaagggatcgccgtgtttggctactccatggcc
gtgtccatcggggggatcttggcttcccgctttctgcacgtggacctgctgcacagcatc
ctgcgatcacccatgagcttctttgagcggaccccaagtgggaacctggtgaaccgcttc
tccaaggagctggacacggtggactccatgatcccggaagtcatcaagatgttcatgggc
tccctgttcaacgtcatcggtgcctgcatcgttatcctgctggccacgcccatcgctgca
atcatcatcccgcccctcggcctcatctacttcttcgtccagaggttctacgtggcctcc
tcccggcagctgaagcgcctcgagtcggtcagccgctccccggtctattcccatttcaac
gagaccttgctgggggtcagcgtcattcgagcctttgaggagcaggagcgcttcatccac
cagagtgacctgaaggtggacgagaaccagaaggcctattaccccagcatcgtggccaac
aggtggctggccgtgcggttggagtgtgtgggcaactgcatcgttctgtgtgctgccctg
ttcgcggtgatctccaggcacagcctcagcgctggcttggtgggcctctcagtgtcttac
tcattgcaggtcaccacgtatttgaactggctggttcggatgtcatctgagatggaaacc
aacatcgtggccgtggagagactcaaggagtattcagagactgagaaggaggcgccctgg
caaatccaggagacagctccgcccagcagctggccccaggtgggccgagtggaattccgg
aactactgcctgcgctaccgagaggacctggacttcgttctcaggcacatcaatgtcacc
atcaatgggggagaaaaggtcggcatcgtggggcggacgggagctgggaagtcgtccctg
accctgggcttatttcggatcaatgagtctgccgaaggagaaatcatcatcgacggcatc
aacatcgccaagatcggcctgcacgacctccgcttcaagatcaccatcattccccaggac
cctgttttgttttcgggttccctccgcatgaacctggacccattcagccagtactcggac
gaagaagtctggacgtccctggagctggcccacctgaaggacttcgtgtcagcccttcct
gacaagctggagcacgaatgtgcagaaggcggggagaacctcagtgttgggcagcgccag
cttgtgtgcctagcccgggccctgcttaggaagacgaagatccttgtgttggatgaggcc
acagcagccgtggacctggaaacggacgacctcatccagtccaccatccggacacagttc
gaggactgcaccgtcctcaccatcgcccatcggctcaacaccatcatggactacacaagg
gtgatcgtcttggacaaaggagaaatccaggagtacggcgccccatcggacctcctgcag
cagagaggtcttttctacagcatggccaaagatgccggcttggtgtga |
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