Nomascus leucogenys (northern white-cheeked gibbon): 100602552
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Entry
100602552 CDS
T03265
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00230
Purine metabolism
nle00670
One carbon pool by folate
nle01100
Metabolic pathways
nle01523
Antifolate resistance
Module
nle_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100602552 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100602552 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100602552 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
nle04147
]
100602552 (ATIC)
Enzymes [BR:
nle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
100602552 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
100602552 (ATIC)
Exosome [BR:
nle04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100602552 (ATIC)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
100602552
NCBI-ProteinID:
XP_003254092
Ensembl:
ENSNLEG00000007215
UniProt:
G1R6I6
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Position
22a:115821929..115860679
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AA seq
592 aa
AA seq
DB search
MAPSQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLQTRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
NYCVLQMDQSYKPGENEVRTLFGLHLSQKRNNGVVNKSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggctcccagccagctcgccttatttagtgtctctgacaaaaccggccttgtggaattt
gcaagaaacctgaccgctcttggtttgaatctggtcgcttccggagggactgcaaaagct
ctcagggatgctggtctggcagtcagagatgtctctgagttgacgggatttcccgaaatg
ttggggggtcgtgtgaaaactttgcatcctgcagtccatgctggaatcttggctcgtaat
attccagaagataatgctgacatggccagacttgatttcaatcttataagagttgttgcc
tgcaatctctatccctttgtaaagacagtggcttctccaggtgtaactgttgaagaggct
gtggagcaaattgacattggtggagtaaccttactgagagctgcagccaaaaaccatgct
cgagtgacagtcgtgtgtgaaccagaggactatgtggtggtgtccacggagatgcagagc
tccgagagtaaggacacctccttgcagactagacgccagttagccttgaaggcattcact
catacggcacaatatgatgaagcaatttcagattatttcaggaaacagtacagcaaaggc
atatctcagatgcccttgcggtatggaatgaaccctcatcagacccctgcccagctgtac
acactgcagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgcgatgctttgaacgcctggcagctggtgaaggaactcaaggaggctttaggtattcca
gccgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactcagt
gaagatgaggccaaagtctgcatggtctatgatctctataaaaccctcacacccatctca
acagcatatgcaagagcaagaggggctgataggatgtcttcatttggtgattttgttgca
ttgtccgatgtttgtgatgtaccaactgcaaaaattatttccagagaagtatctgatggt
ataattgctccaggatatgaagaagaagccttgacaatactttccaaaaagaaaaatgga
aactactgtgtccttcagatggaccagtcttacaaaccaggtgaaaatgaagttcgaact
ctctttggtcttcatttaagccagaagagaaataatggtgtcgtcaacaagtcattattt
agcaatgttgttaccaagaataaagatttgccagagtctgccctccgagacctcatcgta
gccaccattgctgtcaagtacactcagtctaactctgtgtgctacgccaagaacgggcag
gttatcggcattggagcaggacagcagtctcgtatacactgcactcgccttgcaggagat
aaggcaaactattggtggcttagacaccatccacaagtgctttcgatgaagtttaaaaca
ggagtgaagagagcagaaatctccaatgccatcgatcaatatgtgactggaaccattggc
gaggatgaagatttgataaagtggaaggcactgtttgaggaagtccctgagttactcact
gaggcagagaagaaggaatgggttgagaaactgactgaagtttctgtcagctctgatgcc
ttcttccctttccgagataatgtagacagagctaaaaggagtggtgtggcgtacattgcg
gctccctccggttctgctgctgacaaagttgtgattgaggcctgcgacgaactgggaatc
atccttgctcatacgaaccttcggctcttccaccactga
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