Nomascus leucogenys (northern white-cheeked gibbon): 100602656
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Entry
100602656 CDS
T03265
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100602656 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
nle01002
]
100602656 (BACE1)
Enzymes [BR:
nle01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
100602656 (BACE1)
Peptidases and inhibitors [BR:
nle01002
]
Aspartic peptidases
Family A1: pepsin family
100602656 (BACE1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
100602656
NCBI-ProteinID:
XP_003253245
Ensembl:
ENSNLEG00000007342
UniProt:
A0A2I3HBH0
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All DBs
Position
15:17496275..17527437
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AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTSDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRQQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagccctgccctggctcctgctgtggatgggcgcgggagtgctgcctgcccac
ggcacccagcacggcatccggctgcccctgcgcagcggcctggggggcgcacccctgggg
ctgcggctgccccgggagaccgacgaagagcccgaggagcccggccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtcggggcagggctactacgtggagatgacc
gtgggcagccccccgcagacgctcaacatcctggtggatacaggcagcagtaactttgca
gtgggtgctgccccccaccccttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggtgtgtatgtgccctacacccagggcaagtgggaaggggag
ctgggcaccgacctggtaagcatcccccatggccccaacgtcactgtgcgtgccaacatt
gctgccatcactgaatcagacaagttcttcatcaacggctccaactgggaaggcatcctg
gggctggcctatgctgagattgccaggcctgacgactccctggagcctttcttcgactct
ctggtaaagcagacccacgttcccaacctcttctccctgcagctttgtggtgctggcttc
cccctcaaccagtctgaagtgctggcctctgtcggagggagcatgatcattggaggtatc
gaccactcgctgtacacaggcagtctctggtatacacccatccggcgggagtggtattac
gaggtgatcattgtgcgggtggagatcaatggacaggatctgaaaatggactgcaaggag
tacaactatgacaagagcattgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtgtttgaagctgcagtcaaatccatcaaggcagcctcctccacggagaagttccctgat
ggtttctggctaggagagcagctggtgtgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctcactctacctaatgggtgaggttaccaaccagtccttccgcatcacc
atccttccgcagcaatacctgcggccagtggaagatgtggccacgtcccaagacgactgt
tacaagtttgccatctcacagtcatccacgggcactgttatgggagctgttatcatggag
ggcttctacgttgtctttgatcgggcccgaaaacgaattggctttgctgtcagcgcttgc
catgtgcacgatgagttcaggacagcagcggtggaaggcccttttgtcacctcggacatg
gaagactgtggctacaacattccacagacagacgagtcaaccctcatgaccatagcctat
gtcatggctgccatctgcgccctcttcatgctgccactctgcctcatggtgtgtcagtgg
cgctgcctccgctgcctgcgccagcagcatgatgactttgctgatgacatctccctgctg
aagtga
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