KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100603005
Entry
100603005         CDS       T03265                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle03015  mRNA surveillance pathway
nle04022  cGMP-PKG signaling pathway
nle04024  cAMP signaling pathway
nle04114  Oocyte meiosis
nle04218  Cellular senescence
nle04261  Adrenergic signaling in cardiomyocytes
nle04270  Vascular smooth muscle contraction
nle04390  Hippo signaling pathway
nle04510  Focal adhesion
nle04611  Platelet activation
nle04720  Long-term potentiation
nle04728  Dopaminergic synapse
nle04750  Inflammatory mediator regulation of TRP channels
nle04810  Regulation of actin cytoskeleton
nle04910  Insulin signaling pathway
nle04921  Oxytocin signaling pathway
nle04931  Insulin resistance
nle05031  Amphetamine addiction
nle05034  Alcoholism
nle05168  Herpes simplex virus 1 infection
nle05205  Proteoglycans in cancer
nle05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:nle00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    100603005 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    100603005 (PPP1CA)
   04024 cAMP signaling pathway
    100603005 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    100603005 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100603005 (PPP1CA)
   04218 Cellular senescence
    100603005 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100603005 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100603005 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100603005 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100603005 (PPP1CA)
   04921 Oxytocin signaling pathway
    100603005 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100603005 (PPP1CA)
   04270 Vascular smooth muscle contraction
    100603005 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    100603005 (PPP1CA)
   04720 Long-term potentiation
    100603005 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100603005 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100603005 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    100603005 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100603005 (PPP1CA)
   05034 Alcoholism
    100603005 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100603005 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100603005 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nle01009]
    100603005 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:nle03021]
    100603005 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:nle03019]
    100603005 (PPP1CA)
   03041 Spliceosome [BR:nle03041]
    100603005 (PPP1CA)
Enzymes [BR:nle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100603005 (PPP1CA)
Protein phosphatases and associated proteins [BR:nle01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100603005 (PPP1CA)
Transcription machinery [BR:nle03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100603005 (PPP1CA)
Messenger RNA biogenesis [BR:nle03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     100603005 (PPP1CA)
Spliceosome [BR:nle03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100603005 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 100603005
NCBI-ProteinID: XP_003273972
Ensembl: ENSNLEG00000006360
UniProt: G1R3I1
LinkDB
Position
4:complement(86985639..86991310)
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggcaagaatgtacagctgacagagaacgagatccgcggtctgtgcctg
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacatacacggccagtactacgaccttctgcgactatttgagtatggcggt
ttccctcccgagagcaactacctctttctgggggactatgtggacaggggcaagcagtcc
ttggagaccatctgcctgctgctggcctataagatcaagtaccccgagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctatggtttctacgatgagtgc
aagagacgctacaacatcaaactgtggaaaaccttcactgactgcttcaactgcctgccc
atcgcggccatagtggacgaaaagatcttctgctgccatggaggcctgtccccggacctg
cagtccatggagcagattcggcggatcatgcggcccacagacgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaacgac
cgtggcgtctcttttacctttggagccgaggtggtggccaagttcctccacaagcacgac
ttggacctcatctgccgagcacaccaggtggtagaagatggctacgagttctttgccaag
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaacgctggc
gccatgatgagcgtggacgagaccctcatgtgctccttccagatcctcaagcccgccgac
aagaacaaggggaagtacgggcagttcagtggcctgaaccctggaggccgacccatcacc
ccaccccgcaattccgccaaagccaagaaatag

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