KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100604516
Entry
100604516         CDS       T03265                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04014  Ras signaling pathway
nle04015  Rap1 signaling pathway
nle04024  cAMP signaling pathway
nle04062  Chemokine signaling pathway
nle04071  Sphingolipid signaling pathway
nle04145  Phagosome
nle04148  Efferocytosis
nle04151  PI3K-Akt signaling pathway
nle04310  Wnt signaling pathway
nle04360  Axon guidance
nle04370  VEGF signaling pathway
nle04380  Osteoclast differentiation
nle04510  Focal adhesion
nle04520  Adherens junction
nle04530  Tight junction
nle04613  Neutrophil extracellular trap formation
nle04620  Toll-like receptor signaling pathway
nle04650  Natural killer cell mediated cytotoxicity
nle04662  B cell receptor signaling pathway
nle04664  Fc epsilon RI signaling pathway
nle04666  Fc gamma R-mediated phagocytosis
nle04670  Leukocyte transendothelial migration
nle04722  Neurotrophin signaling pathway
nle04810  Regulation of actin cytoskeleton
nle04932  Non-alcoholic fatty liver disease
nle04933  AGE-RAGE signaling pathway in diabetic complications
nle04972  Pancreatic secretion
nle05014  Amyotrophic lateral sclerosis
nle05020  Prion disease
nle05022  Pathways of neurodegeneration - multiple diseases
nle05100  Bacterial invasion of epithelial cells
nle05132  Salmonella infection
nle05135  Yersinia infection
nle05163  Human cytomegalovirus infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05169  Epstein-Barr virus infection
nle05170  Human immunodeficiency virus 1 infection
nle05200  Pathways in cancer
nle05203  Viral carcinogenesis
nle05205  Proteoglycans in cancer
nle05208  Chemical carcinogenesis - reactive oxygen species
nle05210  Colorectal cancer
nle05211  Renal cell carcinoma
nle05212  Pancreatic cancer
nle05231  Choline metabolism in cancer
nle05415  Diabetic cardiomyopathy
nle05416  Viral myocarditis
nle05417  Lipid and atherosclerosis
nle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100604516 (RAC1)
   04015 Rap1 signaling pathway
    100604516 (RAC1)
   04310 Wnt signaling pathway
    100604516 (RAC1)
   04071 Sphingolipid signaling pathway
    100604516 (RAC1)
   04024 cAMP signaling pathway
    100604516 (RAC1)
   04151 PI3K-Akt signaling pathway
    100604516 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    100604516 (RAC1)
   04148 Efferocytosis
    100604516 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100604516 (RAC1)
   04620 Toll-like receptor signaling pathway
    100604516 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    100604516 (RAC1)
   04662 B cell receptor signaling pathway
    100604516 (RAC1)
   04664 Fc epsilon RI signaling pathway
    100604516 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    100604516 (RAC1)
   04670 Leukocyte transendothelial migration
    100604516 (RAC1)
   04062 Chemokine signaling pathway
    100604516 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    100604516 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100604516 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    100604516 (RAC1)
   04380 Osteoclast differentiation
    100604516 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100604516 (RAC1)
   05205 Proteoglycans in cancer
    100604516 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100604516 (RAC1)
   05203 Viral carcinogenesis
    100604516 (RAC1)
   05231 Choline metabolism in cancer
    100604516 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100604516 (RAC1)
   05212 Pancreatic cancer
    100604516 (RAC1)
   05211 Renal cell carcinoma
    100604516 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100604516 (RAC1)
   05163 Human cytomegalovirus infection
    100604516 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100604516 (RAC1)
   05169 Epstein-Barr virus infection
    100604516 (RAC1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100604516 (RAC1)
   05100 Bacterial invasion of epithelial cells
    100604516 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100604516 (RAC1)
   05020 Prion disease
    100604516 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    100604516 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100604516 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    100604516 (RAC1)
   05415 Diabetic cardiomyopathy
    100604516 (RAC1)
   05416 Viral myocarditis
    100604516 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100604516 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100604516 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:nle04131]
    100604516 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nle04147]
    100604516 (RAC1)
   04031 GTP-binding proteins [BR:nle04031]
    100604516 (RAC1)
Membrane trafficking [BR:nle04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    100604516 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    100604516 (RAC1)
  Macropinocytosis
   Ras GTPases
    100604516 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    100604516 (RAC1)
Exosome [BR:nle04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100604516 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   100604516 (RAC1)
  Exosomal proteins of colorectal cancer cells
   100604516 (RAC1)
  Exosomal proteins of bladder cancer cells
   100604516 (RAC1)
GTP-binding proteins [BR:nle04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    100604516 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 100604516
NCBI-ProteinID: XP_030652339
Ensembl: ENSNLEG00000015697
LinkDB
Position
17:complement(31986065..32016570)
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggagctgtaggtaaaacttgcctactg
atcagttacacaaccaatgcatttcctggagaatatatccctactgtctttgacaattat
tctgccaatgttatggtagatggaaaaccggtgaatctgggcttatgggatacagctgga
caagaagattatgacagattacgccccctatcctatccacaaacagatgtgttcttaatt
tgcttttcccttgtgagtcctgcatcatttgaaaatgtccgtgcaaagtggtatcctgag
gtgcggcaccactgtcccaacactcccatcatcctagtgggaactaaacttgatcttagg
gatgataaagacacgatcgagaaactgaaggagaagaagctgactcccatcacctatccg
cagggtctagccatggctaaggagattggtgctgtaaaatacctggagtgctcggcgctc
acacagcgaggcctcaagacagtgtttgacgaagcgatccgagcagtcctctgcccacct
cccgtgaagaagaggaagagaaaatgcctgctgttgtaa

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