Nomascus leucogenys (northern white-cheeked gibbon): 100605499
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Entry
100605499 CDS
T03265
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00760
Nicotinate and nicotinamide metabolism
nle01100
Metabolic pathways
nle04068
FoxO signaling pathway
nle04148
Efferocytosis
nle04152
AMPK signaling pathway
nle04211
Longevity regulating pathway
nle04213
Longevity regulating pathway - multiple species
nle04218
Cellular senescence
nle04310
Wnt signaling pathway
nle04922
Glucagon signaling pathway
nle04936
Alcoholic liver disease
nle05031
Amphetamine addiction
nle05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
100605499 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100605499 (SIRT1)
04068 FoxO signaling pathway
100605499 (SIRT1)
04152 AMPK signaling pathway
100605499 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100605499 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
100605499 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100605499 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
100605499 (SIRT1)
04213 Longevity regulating pathway - multiple species
100605499 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100605499 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
100605499 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100605499 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
nle03036
]
100605499 (SIRT1)
03029 Mitochondrial biogenesis [BR:
nle03029
]
100605499 (SIRT1)
Enzymes [BR:
nle01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
100605499 (SIRT1)
Chromosome and associated proteins [BR:
nle03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
100605499 (SIRT1)
Mitochondrial biogenesis [BR:
nle03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
100605499 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
100605499
NCBI-ProteinID:
XP_030654379
Ensembl:
ENSNLEG00000012003
LinkDB
All DBs
Position
18:17774306..17811356
Genome browser
AA seq
747 aa
AA seq
DB search
MADEAALALQPSGSPSAAGAEREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREV
PAAAAGCPAAAAALGREAEAAAAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPSLADNF
YDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRP
RIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDI
NTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIE
YFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRII
QCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPE
QFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLG
DCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHISEDSSS
PERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDL
KNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSD
SEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDIPERAGGAGFGTD
GDDQEAINEAISMKQEVTDMNCPSNKS
NT seq
2244 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggccctcgcccttcagcccagcggctccccctcggcggcgggggcc
gagagggaggccgcgtcgtcccccgccggggagccgctccgcaagaggccgcggagagat
ggtcccggcctcgagcggagcccgggcgagcccggtggggcggccccagagcgtgaggtg
cccgcggcggccgccggctgcccggctgcggcggcggcgctggggcgggaggcggaggca
gcggcggcggcggcggcgggtggggagcaagaggcccaggcgactgcggcggctggggaa
ggagacaatgggccgggcctgcagggcccatctcgggagccatcgctggccgacaacttc
tacgacgaagacgacgacgacgagggcgaggaggaggaagaggcggcggcggcggcgatt
gggtaccgagataaccttctgttcggtgatgaaattatcactaatggttttcattcctgt
gaaagtgatgaggaggatagagcctcacatgcaagctctagtgattggactccaaggcca
cggataggtccatatacttttgttcagcaacatcttatgattggcacagatcctcgaaca
attcttaaagatttattgccggaaacaattcctccacctgagttggatgatatgacactg
tggcagattgttattaatatcctttcagaaccaccaaaaaggaaaaaaagaaaagatatt
aatacaattgaagatgctgtgaaattactgcaagagtgcaaaaaaattatagttctaact
ggagctggggtgtctgtttcatgtggaatacctgacttcaggtcaagggatggtatttat
gctcgccttgctgtagacttcccagatcttccagatcctcaagcgatgtttgatattgaa
tatttcagaaaagatccaagaccattcttcaagtttgcaaaggaaatatatcctggacaa
ttccaaccatctctctgtcacaaattcatagctttgtcagataaggaaggaaaactactt
cgcaactatacccagaacatagacacgctggaacaggttgcgggaatccaaaggataatt
cagtgtcatggttcctttgcaacagcatcttgcctgatttgtaaatacaaagttgactgt
gaagctgtacgaggagatatttttaatcaggtagttcctcgatgtcctaggtgcccagct
gatgagccgcttgctatcatgaaaccagagattgtgttttttggtgaaaatttaccagaa
cagtttcatagagccatgaagtatgacaaagatgaagttgaccttctcattgttattggg
tcttccctcaaagtaagaccagtagctctaattccaagttccataccccatgaagtgcct
cagatattaattaatagagaacctttgcctcatctgcattttgatgtagagcttcttgga
gactgtgatgtcataattaatgaattgtgtcataggttaggtggtgaatatgccaaactt
tgctgtaaccctgtaaagctctcagaaattactgaaaaacctccacgaacacaaaaggaa
ttggcttatttgtcagagttgccacccacacctcttcatatttcggaagactcaagttca
ccagaaagaacttcaccaccagattcttcagtgattgtcacacttttagaccaagcagct
aagagtaatgatgatttagatgtgtctgaatcaaaaggttgtatggaagaaaaaccacag
gaagtacaaacttctaggaatgttgaaagtattgctgaacagatggaaaatccggatttg
aagaatgttggttccagtactggggagaaaaatgaaagaacttcagtggctggaacagtg
agaaaatgctggcctaatagagtggcaaaggagcagattagtaagcggcttgatggtaat
cagtatctgtttttgccaccaaatcgttacattttccatggcgctgaggtatattcagac
tctgaagacgacgtcttatcctctagttcttgtggcagtaacagtgatagtgggacatgc
cagagtccaagtttagaagaacccatggaggatgaaagtgaaattgaagaattctacaat
ggcttagaagatgagcctgatattccagagagagctggaggagctggatttgggactgat
ggagatgatcaagaggcaattaatgaagctatatctatgaaacaggaagtaacagacatg
aactgtccatcaaacaaatcatag
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