Nomascus leucogenys (northern white-cheeked gibbon): 100606063
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Entry
100606063 CDS
T03265
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00310
Lysine degradation
nle01100
Metabolic pathways
nle05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100606063 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100606063 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
nle03036
]
100606063 (DOT1L)
Enzymes [BR:
nle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
100606063 (DOT1L)
Chromosome and associated proteins [BR:
nle03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100606063 (DOT1L)
HMT complexes
Dot1-containing complex
100606063 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
100606063
NCBI-ProteinID:
XP_030651734
Ensembl:
ENSNLEG00000002122
LinkDB
All DBs
Position
17:complement(93551510..93623993)
Genome browser
AA seq
1537 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDSKSNAATPTKGP
EGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTA
NPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGTAQQLLSHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRSQSLQLL
KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCAKFSLPHLSSMSPELSMNGQAAGY
ELCGALSRPSSKQNTPQYLASPLDQEVVPCTPSHGGRPRLEKLSGLAAPDYTRLSPAKIV
LRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL
AGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST
PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA
EPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGATQGPL
PEASKGDLPSDSGFSDPESEAKRRIVFTIATGAGSAKQSPSSKHSPLTSSARGDCVLSHG
QDSRKRGRRKRASTGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI
TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI
ERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSP
LQASSTLSQNSLFAFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGG
GLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLK
GEGSRGKEAGEGGLPLCGPTDKTPLLTCKAAKARDRELDLKNGHNLFISAAAVPPGSLLS
GPGLAPAASSAGSVASSAQTHRPFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS
VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN
NT seq
4614 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgagactgaagtcgcccgtgggggctgagcccgccgtgtac
ccgtggccgctgccggtctacgataaacatcacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaagaaatcccggatctcaagctcgctatggagaattacgtttta
attgactatgacaccaaaagcttcgagagcatgcagaggctctgtgacaagtacaaccgt
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
cggccgtccaccgggctcctgcgccacatcctgcagcaggtctacaaccactcggtgacc
gaccccgagaagctcaacaactacgagcccttctcccccgaggtgtatggggagacctcc
ttcgacctggtggcccagatgattgacgagatcaagatgaccgacgacgacctgtttgtg
gacttggggagcggtgtgggccaggtcgtgctccaggttgccgctgccaccaactgcaaa
catcactatggcgtcgagaaagcagacatcccggccaagtatgcggagaccatggaccgc
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacattggagaga
ggcgatttcctctcagaagagtggagggagcgaatcgccaacacgagtgttatatttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaaaccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtggtggagctctcgcccctgaag
ggctcggtgtcgtggacggggaagccagtctcctactacctgcacactatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaggaggca
gcccggcgccgccagcagcgcgacagcaagagcaatgcagccacgcccactaagggccca
gagggcaaggtggccggccccgcggacgcccccatggactctggtgctgaggaagagaag
gcgggagcagccaccgtgaagaagccgtctccctccaaagcccgcaagaagaagctaaac
aagaaggggaggaagatggccggccgcaagcgtgggcgccccaagaagatgaacactgca
aaccccgagcggaagcccaagaagaaccaaactgcactggatgccctgcacgctcagacc
gtgtctcagacggcggcctcctcaccccaggatgcctacagatcccctcacagcccgttc
taccagctacctccgagcgtgcagcggcactcccccaacccgctgctggtggcgcccacc
ccgcccgcgctgcagaagctgctagagtccttcaagatccagtacctgcagttcctggca
tacacaaagaccccccagtacaaggccagcctgcaggagctgctgggccaggagaaggag
aagaatgcccagctcctgggcacggctcagcagctcctcagccactgccaggcccagaag
gaggagatcaggagactgttccagcaaaaattggatgagctgggcgttaaggcgctgacc
tacaacgacctgattcaagcgcagaaggagatctctgcccataaccagcagctgcgggag
cagtcggagcagctggagcaggacaaccgcgcgctccgcagccagagcttgcagctgctc
aaggctcgctgcgaggagctgcagctggactgggccacgctgtctctagagaagctgctg
aaggagaagcaggccttgaagagccagatctcagagaagcagaggcactgcctggagctg
cagatcagcattgtggagctagagaagagccagcggcagcaggagctcctgcagctcaag
tcctgtgtgccgcctgacgacgccttgtccctgcacctgcgtgggaagggcgccctgggc
cgcgagctggagcctgatgccagccggctgcacctggagctggactgcgccaagttctcg
ctgcctcacttgagcagcatgagcccggagctctccatgaacggccaggctgctggctat
gagctctgcggcgcgctgagccggccctcgtccaagcagaacacaccccagtacctggcc
tcacccctggaccaggaggtggtgccctgcacccccagccatggcggccggccacgcctg
gagaagctctctggcctagccgcacccgactacactaggctgtcccccgccaagattgtg
ctgaggcggcacctgagccaggaccacacggtgcccggcaggccggccgccagtgagctg
cactcgagagctgagcacaccaaggagaacggccttccctaccagagccccagcgtgcct
ggcagcatgaagctgagccctcaggacccgcggcccctgtcccctggggccttgcagctt
gctggagagaagagcagtgagaagggcctgagagagcgcgcctacggcagcagcggggaa
ctcatcaccagcctgcccatcagcatcccgctcagcaccgtgcagcccaacaagctcccg
gtcagcatccccctggccagcgtggtgctgcccagccgcgccgagagggcgaggagcacc
cccagtcctgtgctgcagccccgtgacccctcgtccacacttgaaaagcagattggtgct
aatgcccacggtgctgggagcagaagccttgccctggcccccgcaggcttctcctacgct
ggctcggtggccatcagcggggccttggcgggcagcccggcctctctcacacctggagcc
gagccggccaccttggatgagtcctccagctctgggagcctttttgccaccgtggggtcc
cgcagctccacgccacagcaccccctgctgctggcacagccccggaactcgctcccggcc
tctcccgcccaccagctctcctccagtccccggcttggtggggccacccagggcccgctc
cccgaggccagcaagggggacctgccctccgattccggcttctcagatcctgagagtgaa
gccaagaggaggatcgtgttcaccatcgccactggtgcgggcagtgccaagcagtcgccc
tccagcaagcacagccccctgacctccagcgcccgtggggactgtgtgctgagccacggg
caggacagccgcaagcgcggccggcggaagcgagcatctacggggacgcccagcttgagt
gcaggcgtgtcccccaagcgccgagccctgccatctgtcgctggccttttcacacagccg
tcggggtctcccctcaacctcaactccatggtcagtaacatcaaccagcccctggagatt
acagccatctcgtcccccgagacctccctgaagagctcccctgtgccctaccaggaccac
gaccagccccccgtgctcaagaaggagcggcctctgagccagaccaatggggcacactac
tccccactcacctcagatgaggagccaggctctgaggacgagcccagcagtgcccgaatt
gagagaaaaattgcaacaatctccttagaaagcaaatctcccccgaaaaccttggaaaat
ggtggtggcttggcgggaaggaagccagcgcctgccggcgagccagtcaatagcagcaag
tggaagtccaccttctcgcccatctctgacatcggcctggccaagtctgcagacagcccg
ctgcaggccagctccaccctcagccagaactccctgttcgcgttccggcccgccctggag
gagccctctgccgatgccaagctggccgctcaccccaggaaaggctttcccggctccctg
tcgggggctgatggactcagcccgggcaccaaccctgccaacggctgcaccttcggcggg
ggcctggccgcggacctgagtttacacagcttcagtgatggtgcttctcttccccacaag
ggccccgaggcggccggcctgagctccccgctgagcttcccctcgcagcgcggcaaggag
ggctcggacgccaaccctttcctgagcaagaggcagctggacggcctggctgggctgaag
ggcgagggcagccgcggcaaggaggcaggggagggcggcctgccgctgtgcgggcccacg
gacaagaccccgctgctgacctgcaaggccgccaaggcccgggaccgcgagctcgacctc
aagaatggccacaacctcttcatctctgcggcggccgtgcctcccggaagcctcctcagc
ggccccggtctggccccggcggcgtcctccgcaggcagcgtggcgtcctccgcccagaca
caccggcccttcctgggccccttcccgccgggaccgcagttcgcgctcggccccatgtcc
ctgcaggccaacctcggctccgtggccggctcctccgtgctgcagtcgctgttcagctct
gtgccggccgccgcaggcctggtgcacgtgtcgtccgctgccaccagactgaccaactcg
cacgccatgggcagcttttccggggtggcaggcggcacagttggaggtaactag
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integrated database retrieval system
