KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100607264
Entry
100607264         CDS       T03265                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04020  Calcium signaling pathway
nle04022  cGMP-PKG signaling pathway
nle04114  Oocyte meiosis
nle04218  Cellular senescence
nle04310  Wnt signaling pathway
nle04360  Axon guidance
nle04370  VEGF signaling pathway
nle04380  Osteoclast differentiation
nle04625  C-type lectin receptor signaling pathway
nle04650  Natural killer cell mediated cytotoxicity
nle04658  Th1 and Th2 cell differentiation
nle04659  Th17 cell differentiation
nle04660  T cell receptor signaling pathway
nle04662  B cell receptor signaling pathway
nle04720  Long-term potentiation
nle04724  Glutamatergic synapse
nle04728  Dopaminergic synapse
nle04921  Oxytocin signaling pathway
nle04922  Glucagon signaling pathway
nle04924  Renin secretion
nle05010  Alzheimer disease
nle05014  Amyotrophic lateral sclerosis
nle05020  Prion disease
nle05022  Pathways of neurodegeneration - multiple diseases
nle05031  Amphetamine addiction
nle05152  Tuberculosis
nle05163  Human cytomegalovirus infection
nle05166  Human T-cell leukemia virus 1 infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05170  Human immunodeficiency virus 1 infection
nle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nle05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100607264 (PPP3CB)
   04310 Wnt signaling pathway
    100607264 (PPP3CB)
   04370 VEGF signaling pathway
    100607264 (PPP3CB)
   04020 Calcium signaling pathway
    100607264 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    100607264 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100607264 (PPP3CB)
   04218 Cellular senescence
    100607264 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100607264 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    100607264 (PPP3CB)
   04660 T cell receptor signaling pathway
    100607264 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    100607264 (PPP3CB)
   04659 Th17 cell differentiation
    100607264 (PPP3CB)
   04662 B cell receptor signaling pathway
    100607264 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100607264 (PPP3CB)
   04921 Oxytocin signaling pathway
    100607264 (PPP3CB)
   04924 Renin secretion
    100607264 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100607264 (PPP3CB)
   04728 Dopaminergic synapse
    100607264 (PPP3CB)
   04720 Long-term potentiation
    100607264 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    100607264 (PPP3CB)
   04380 Osteoclast differentiation
    100607264 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100607264 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100607264 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    100607264 (PPP3CB)
   05163 Human cytomegalovirus infection
    100607264 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100607264 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100607264 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100607264 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    100607264 (PPP3CB)
   05020 Prion disease
    100607264 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    100607264 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100607264 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100607264 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nle01009]
    100607264 (PPP3CB)
Enzymes [BR:nle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100607264 (PPP3CB)
Protein phosphatases and associated proteins [BR:nle01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100607264 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 100607264
NCBI-ProteinID: XP_030654094
Ensembl: ENSNLEG00000029785
LinkDB
Position
18:complement(23540047..23599148)
AA seq 534 aa
MAAPEPARAVPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDERLIYGNKKVGSAAARKEIIRNKIR
AIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGF
SPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHTAQ
NT seq 1605 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgtaccgcccccgcccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgtccctttccccccaacacatcgcttgacatct
gaagaagtatttgatttggatgggatacccagggttgatgttctgaagaaccacttggtg
aaagaaggtcgagtagatgaagaaattgcgcttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaggtagaagctccaatcacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaatacg
cgatacctttttcttggcgattatgtggacagaggttattttagtatagagtgtgtcttg
tatttatgggttctgaagattctatacccaagcacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaagtattca
gaaagagtctatgaagcttgtatggaagcttttgatagtttgcctcttgctgcactttta
aaccaacagtttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgtta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttactggttgcctaattttatggatgtcttcacg
tggtctttaccttttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactaatgactgaaggtgaagaccagtttgatgaacggctcatatat
ggcaataaaaaagtaggttcagctgcagcccggaaagaaataataagaaacaaaattcga
gcaattggcaagatggcaagagtcttctctgttctcagggaggagagtgaaagtgtgctg
acactcaagggcctgactcccacagggatgttgcctagtggagtgttagctggaggacgg
cagaccctgcaaagtgccacagttgaggctattgaggctgaaaaagcaatacgaggattc
tctccaccacatagaatctgcagttttgaagaggcaaagggtttggataggatcaatgag
agaatgccacctcggaaagatgctgtacagcaagatggtttcaattctctgaacaccgca
catgccactgagaaccacgggacgggcaaccatactgcccagtga

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