KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 101176289
Entry
101176289         CDS       T03265                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoform X7
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01522  Endocrine resistance
nle04015  Rap1 signaling pathway
nle04020  Calcium signaling pathway
nle04024  cAMP signaling pathway
nle04072  Phospholipase D signaling pathway
nle04261  Adrenergic signaling in cardiomyocytes
nle04270  Vascular smooth muscle contraction
nle04540  Gap junction
nle04611  Platelet activation
nle04713  Circadian entrainment
nle04714  Thermogenesis
nle04724  Glutamatergic synapse
nle04726  Serotonergic synapse
nle04728  Dopaminergic synapse
nle04730  Long-term depression
nle04750  Inflammatory mediator regulation of TRP channels
nle04911  Insulin secretion
nle04912  GnRH signaling pathway
nle04913  Ovarian steroidogenesis
nle04915  Estrogen signaling pathway
nle04916  Melanogenesis
nle04918  Thyroid hormone synthesis
nle04921  Oxytocin signaling pathway
nle04922  Glucagon signaling pathway
nle04923  Regulation of lipolysis in adipocytes
nle04924  Renin secretion
nle04925  Aldosterone synthesis and secretion
nle04926  Relaxin signaling pathway
nle04927  Cortisol synthesis and secretion
nle04928  Parathyroid hormone synthesis, secretion and action
nle04934  Cushing syndrome
nle04935  Growth hormone synthesis, secretion and action
nle04961  Endocrine and other factor-regulated calcium reabsorption
nle04962  Vasopressin-regulated water reabsorption
nle04970  Salivary secretion
nle04971  Gastric acid secretion
nle04972  Pancreatic secretion
nle04976  Bile secretion
nle05012  Parkinson disease
nle05030  Cocaine addiction
nle05031  Amphetamine addiction
nle05032  Morphine addiction
nle05034  Alcoholism
nle05142  Chagas disease
nle05146  Amoebiasis
nle05163  Human cytomegalovirus infection
nle05165  Human papillomavirus infection
nle05200  Pathways in cancer
nle05207  Chemical carcinogenesis - receptor activation
nle05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101176289 (GNAS)
   04020 Calcium signaling pathway
    101176289 (GNAS)
   04072 Phospholipase D signaling pathway
    101176289 (GNAS)
   04024 cAMP signaling pathway
    101176289 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101176289 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101176289 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    101176289 (GNAS)
   04922 Glucagon signaling pathway
    101176289 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    101176289 (GNAS)
   04912 GnRH signaling pathway
    101176289 (GNAS)
   04913 Ovarian steroidogenesis
    101176289 (GNAS)
   04915 Estrogen signaling pathway
    101176289 (GNAS)
   04921 Oxytocin signaling pathway
    101176289 (GNAS)
   04926 Relaxin signaling pathway
    101176289 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    101176289 (GNAS)
   04918 Thyroid hormone synthesis
    101176289 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    101176289 (GNAS)
   04916 Melanogenesis
    101176289 (GNAS)
   04924 Renin secretion
    101176289 (GNAS)
   04925 Aldosterone synthesis and secretion
    101176289 (GNAS)
   04927 Cortisol synthesis and secretion
    101176289 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101176289 (GNAS)
   04270 Vascular smooth muscle contraction
    101176289 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    101176289 (GNAS)
   04971 Gastric acid secretion
    101176289 (GNAS)
   04972 Pancreatic secretion
    101176289 (GNAS)
   04976 Bile secretion
    101176289 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    101176289 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101176289 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    101176289 (GNAS)
   04728 Dopaminergic synapse
    101176289 (GNAS)
   04726 Serotonergic synapse
    101176289 (GNAS)
   04730 Long-term depression
    101176289 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101176289 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101176289 (GNAS)
   04714 Thermogenesis
    101176289 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101176289 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    101176289 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101176289 (GNAS)
   05165 Human papillomavirus infection
    101176289 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101176289 (GNAS)
   05142 Chagas disease
    101176289 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    101176289 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    101176289 (GNAS)
   05031 Amphetamine addiction
    101176289 (GNAS)
   05032 Morphine addiction
    101176289 (GNAS)
   05034 Alcoholism
    101176289 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101176289 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101176289 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101176289 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nle04147]
    101176289 (GNAS)
   04031 GTP-binding proteins [BR:nle04031]
    101176289 (GNAS)
Exosome [BR:nle04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101176289 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   101176289 (GNAS)
  Exosomal proteins of colorectal cancer cells
   101176289 (GNAS)
  Exosomal proteins of bladder cancer cells
   101176289 (GNAS)
GTP-binding proteins [BR:nle04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    101176289 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Roc Gtr1_RagA GTP_EFTU TniB AAA_29 Peptidase_S49_N FtsK_SpoIIIE
Other DBs
NCBI-GeneID: 101176289
NCBI-ProteinID: XP_003277551
Ensembl: ENSNLEG00000009392 ENSNLEG00000018276
LinkDB
Position
13:complement(5237392..5309155)
AA seq 379 aa
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNGDEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVM
NVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQ
DLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNM
VIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEF
ARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRV
FNDCRDIIQRMHLRQYELL
NT seq 1140 nt   +upstreamnt  +downstreamnt
atgggctgcctcgggaacagtaagaccgaggaccagcgcaacgaggagaaggcgcagcgt
gaggccaataaaaagatcgagaagcagctgcagaaggacaagcaggtctaccgggccacg
caccgcctgctgctgctgggtgctggagaatctggtaaaagcaccattgtgaagcagatg
aggatcctgcatgttaatgggtttaatggagatgagaaggcaaccaaggtgcaggacatc
aaaaacaacctgaaagaggcgatcgaaaccattgtggccgccatgagcaacctggtgccc
cccgtggagctggccaaccccgagaaccagttcagagtggactacattctgagtgtgatg
aacgtgcctgactttgacttccctcccgaattctatgagcatgccaaggctctgtgggag
gatgaaggagtgcgtgcctgctacgaacgctccaacgagtaccagctgatcgactgtgcc
cagtacttcctggacaagatcgatgtgatcaagcaggccgactatgtgccgagcgatcag
gacctgcttcgctgccgtgtcctgacttctggaatctttgagaccaagttccaggtggac
aaagtcaacttccacatgtttgacgtgggtggccagcgcgatgaacgccgcaagtggatc
cagtgcttcaatgatgtgactgccatcatcttcgtggtggccagcagcagctacaacatg
gtcatccgggaggacaaccagaccaaccgcctgcaggaggctctgaacctcttcaagagc
atctggaacaacagatggctgcgcaccatctctgtgattctgttcctcaacaagcaagat
ctgctcgctgagaaagtccttgctgggaaatcgaagattgaggactactttccagaattt
gctcgctacactactcctgaggatgctactcccgagcccggagaggacccacgcgtgacc
cgggccaagtacttcattcgagatgagtttctgaggatcagcactgccagtggagatggg
cgtcactactgctaccctcatttcacctgcgctgtggacactgagaacatccgccgtgtg
ttcaacgactgccgtgacatcattcagcgcatgcaccttcgtcagtacgagctgctctaa

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