KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 115838359
Entry
115838359         CDS       T03265                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04120  Ubiquitin mediated proteolysis
nle04380  Osteoclast differentiation
nle04630  JAK-STAT signaling pathway
nle04668  TNF signaling pathway
nle04910  Insulin signaling pathway
nle04917  Prolactin signaling pathway
nle04920  Adipocytokine signaling pathway
nle04930  Type II diabetes mellitus
nle04931  Insulin resistance
nle04932  Non-alcoholic fatty liver disease
nle04935  Growth hormone synthesis, secretion and action
nle05160  Hepatitis C
nle05164  Influenza A
nle05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:nle00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    115838359 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    115838359 (SOCS3)
   04668 TNF signaling pathway
    115838359 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    115838359 (SOCS3)
   04920 Adipocytokine signaling pathway
    115838359 (SOCS3)
   04917 Prolactin signaling pathway
    115838359 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    115838359 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    115838359 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    115838359 (SOCS3)
   05164 Influenza A
    115838359 (SOCS3)
   05168 Herpes simplex virus 1 infection
    115838359 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    115838359 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    115838359 (SOCS3)
   04931 Insulin resistance
    115838359 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:nle04121]
    115838359 (SOCS3)
Ubiquitin system [BR:nle04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     115838359 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 115838359
NCBI-ProteinID: XP_030683808
LinkDB
Position
14:88334056..88337339
AA seq 225 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgcagtgaccggcggcgaggcgaacctgctgctc
agcgccgagcccgccggcacctttctgatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtctgggaccaagaacctgcgaatccagtgtgaggggggc
agcttctctctgcagagcgatccccggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcaccactacatgccgccccctggagccccctccttcccctcgccacct
actgaaccctcctccgaggtgcccgagcagccgtctgcccagccactccctgggagtccc
cccagaagagcctattacatctactccgggggcgagaagatccccctggtgttgagccgg
cccctctcctccaacgtggccactcttcagcatctctgtcggaagaccgtcaacggccac
ctggactcctatgagaaagtcacccagctgccggggcccattcgggagttcctggaccag
tacgatgccccgctttaa

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