KEGG   Neisseria leonii: ORY85_00055
Entry
ORY85_00055       CDS       T10281                                 
Symbol
cysG
Name
(GenBank) siroheme synthase CysG
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
nln  Neisseria leonii
Pathway
nln00860  Porphyrin metabolism
nln01100  Metabolic pathways
nln01110  Biosynthesis of secondary metabolites
nln01120  Microbial metabolism in diverse environments
nln01240  Biosynthesis of cofactors
Module
nln_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:nln00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    ORY85_00055 (cysG)
Enzymes [BR:nln01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     ORY85_00055 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     ORY85_00055 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     ORY85_00055 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Shikimate_DH HTH_38 Hydrolase_6 CIS_TMP Yop-YscD_cpl
Other DBs
NCBI-ProteinID: WWV74833
LinkDB
Position
complement(12640..14016)
AA seq 458 aa
MNYFPLFADLRGEPVLVVGGGTVAERKIAPLLEAGASVRVVARKLNSQVRAWADEGRLNW
VANEFADGMVHDVLLVIAATDDETLNRHVSQAAKAAKRLVNVVDRQELCTFITPAVIDRS
PLQIAVSSNGTSPVLSRRVRQAVEKCVPFSFGTMAQLAAEARDDVKAALPDLARRRLFWE
QLFDGVFADYCAQGRLNDARRELKQRLAADTPPQGSVCLVGAGPGDAGLLTLHALHAIQA
ADVVLYDALVSDEVMRLVRKDAEKICVGKRAQGHQVRQEETNRLLLEHARSGRRVVRLKG
GDPFVFGRGGEELQVLAEAGIPFRIVPGITAALGATAYAGIPLTHRDYAQSVQFITGHCR
ADGSDVAWQNFAQNNQTLAVYMGTIRAAEIAAQLIRHGRAADTPVAIISNGTRRNQSVIS
GRLDRLADLAARAEAPALMVIGQTAALHGQLDWFGKRD
NT seq 1377 nt   +upstreamnt  +downstreamnt
atgaattattttcctttatttgccgacttgcgcggcgagccggtgctggtggtcggcggc
ggcacggtggccgaacgcaaaatcgcgccgctgctggaagcaggtgcttcggtacgcgtg
gttgcccgaaagcttaatagtcaagttcgtgcatgggcagacgaaggccgtctgaattgg
gtggcaaacgaatttgcagacggtatggttcatgatgttctgctggtcatcgccgctacc
gatgacgaaacgctcaatcggcacgtttctcaggccgccaaagccgccaagcggctggtc
aatgtggtagatcggcaggagctgtgcacgtttatcaccccggccgtcatcgaccgctcg
ccgctgcaaatcgccgtgtcgagcaacggcacatcgccggtattgagccgccgcgtgcgg
caggccgtcgaaaaatgcgtgccgttttcgttcggcacaatggcgcagctggcagccgaa
gcgcgtgatgatgtgaaagccgccctgcccgatttggcgcgccgccgcctgttttgggag
cagctgttcgacggggtgtttgccgattattgcgcacaaggccgtctgaacgatgcccgc
cgcgaactgaaacagcggctggctgccgatacgccgccgcagggttcggtgtgtctggtc
ggcgcggggccgggcgatgccgggctgctcacactgcacgcgctacacgccattcaggca
gccgatgtggtgctgtatgacgcgctggtgagtgatgaggtgatgcggctggtgcgcaaa
gatgcggaaaaaatctgcgtgggcaaacgggcgcagggtcatcaggtgcggcaggaggaa
accaaccgcctgctgctggaacacgcccgcagcggccggcgcgtggtgcgtctcaaaggc
ggcgacccgttcgttttcgggcgcggcggcgaagaattgcaggtgctggccgaagcgggg
attccgttccgcatcgtgccgggcattaccgccgcgctgggggctacggcttatgccggt
atcccgctgacccaccgcgattatgcccaatcggtgcagtttatcaccggccactgccgc
gccgacggcagcgatgtcgcttggcagaatttcgcccaaaacaatcaaacgctggcagtg
tatatgggaaccatccgcgcggccgaaattgccgcacaactgatccgccacggccgcgcc
gccgacacgcccgtcgccatcatcagcaacggtacgcgccgcaaccagagcgtcatcagc
ggccgtctcgaccgtctggccgatttggccgcacgcgccgaggctcccgccctgatggtt
atcggacagaccgccgcgctgcacgggcagctggactggttcggcaagcgggactga

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