Neisseria macacae: MON40_04245
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Entry
MON40_04245 CDS
T08217
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
nmb
Neisseria macacae
Pathway
nmb00230
Purine metabolism
nmb01100
Metabolic pathways
nmb01110
Biosynthesis of secondary metabolites
Module
nmb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nmb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MON40_04245 (purL)
Enzymes [BR:
nmb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MON40_04245 (purL)
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GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
UNV85728
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Position
complement(885257..889267)
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AA seq
1336 aa
AA seq
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MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLKSEFWYFVGSEKALDAATVEKLQAL
LAAQSVKETPEAREGLHLFLVTPRLGTISPWASKATNIAENCGLEGIERIERGMAVWLEG
RLNDEQKQQWAALLHDRMTESVLPDFQMASKLFHHLESETFSTVDVLGGGKEALVKANTE
MGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQQKSL
FGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYPNAAENQGYRFHEEDTHIIMKVETH
NHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQPWELDYGKP
EHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSI
QAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMNTGTNDASLDFNSVQRGNPEIERR
AQEVIDRCWQLGDQNPIISIHDVGAGGLSNAFPELVNDAGRGAVFKLREVPLEEHGLNPL
QIWCNESQERYVLSILEKDLDTFRAICERERCPFTVVGTATDDGHLKVRDDLFSNNPVDL
PLNVLLGKPPKTTRSDKTVRSSEKPFNAGNIDITEAAYRVLRLPAVAAKNFLITIGDRSI
GGMTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPTVALFDAPASGRMCVGEAI
TNIAAVNIGGIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSM
KTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEDSVLLFIDLGFGKARMGG
SAFGQVYNNMSGDAPDLDDTGRLKAFYSVIQQLVAEDKLLAYHDRSDGGLFATLAEMAFA
GRCGLDITLGSILFATMIATYTPAQIDHDLSLVNAGSIISTKENIIRSLFNEELGAVLQV
RAEDTDYVLKQFDKKEFFVNKGGFSPRKIGKFASHYIGTINPTSDRLVITAADETLFDQT
RADLQRAWQETSHAIQRLRDNPACADSEFALIGDNERSALFADAKFDVNEDIAAPFVNSG
AKPKIAILREQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRVHLADFKMLAACGGFSYG
DVLGAGEGWAKSILFHPALRDQFAAFFADPNTLTLGVCNGCQMVSNLAEIIPGTAGWPKF
KRNLSEQFEARLSMVHVPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGKISDGLGIA
LQYVDGQNQVTQTYPLNPNGSPQGIAGVTNADGRVTIMMPHPERVYRAAQMSWKPEDWTE
LSGWYRLFAGARKALG
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgtctgttgttttgcccttgcgcggcgttaccgccctttccgatttccgtgttgaaaaa
ctcttgcaaaaagcggccgcactcggcctgcccgaagtgaaactgaaaagcgaattttgg
tatttcgtcggcagcgagaaagcactggatgccgcgactgttgaaaaactgcaagccttg
ttggcggcgcaaagcgttaaagaaacgcccgaagcgcgcgagggcttgcatttatttttg
gtaacgccccgtttgggcacgatttcgccgtgggcttccaaggcgaccaatatcgcggaa
aactgcggtttggaaggcatagagcgcatcgaacgcggcatggcggtatggctggaaggt
cgtctgaatgatgaacagaaacagcaatgggcggctttgctgcacgaccgcatgaccgaa
tctgtgctgcccgattttcagatggcctccaaattattccaccatctcgaatccgaaact
ttctctaccgttgatgttttaggcggcggtaaagaggctttggttaaagccaataccgaa
atgggtttggcactctccgccgacgaaatcgattatctggttgaaaactatcaggctttg
cagcgcaatccgtccgatgtggagctgatgatgttcgcgcaggcaaacagcgaacactgc
cgccacaaaattttcaacgccgatttcatcctcaacggcgaaaagcagcagaaatcgctc
ttcggcatgatacgcgacacgcacaacgcgcatcccgaaggcacggtcgttgcctataaa
gacaattcgtccgtgatcgaaggcgcaaaaattgagcgtttctatccgaatgcggcggaa
aaccaaggttaccgtttccacgaggaagacacgcatatcatcatgaaagtggaaacgcac
aaccacccgaccgccatcgcgccgtttgcaggcgcggcaacgggcgcgggcggcgaaatc
cgcgacgaaggcgcgacgggcaaaggttcgcgccctaaagcgggcttgaccggctttacc
gtctccaacctcaacattcccgacctcaaacagccgtgggaactagactacggcaagccg
gaacatatttcctcgccgttggacatcatgattgaaggccctatcggcggcgcggcgttc
aacaacgaattcggccgcccgaacctcttgggctacttccgcacttttgaagagaagttt
gacggtcaggttcgcggctaccacaaaccgattatgattgccggcggcttgggcagcatt
caggcgcagcagacgcataaagacgaaatccccgaaggcgcattgctgatccaactgggc
ggtccgggcatgctcatcggcttgggcggcggcgcggcttcttcgatgaataccggtaca
aatgacgcgtctttggacttcaactccgtacaacgcggcaaccctgaaatcgaacgccgc
gcgcaggaagtgatcgaccgctgctggcagctcggcgaccaaaacccgattatctccatc
cacgacgtcggcgcgggcggcctgtccaacgccttccccgaactcgttaacgatgccgga
cgcggcgcggtattcaagctgcgcgaagtgccgctggaagagcacggcctcaacccgctg
caaatctggtgcaacgaatcgcaagagcgttatgtgttgtcgattttggaaaaagatttg
gataccttccgcgccatctgcgaacgcgaacgctgcccgtttaccgtggtcggcacggcg
accgacgacggtcatttgaaagtacgcgacgatttgttctccaacaaccccgtcgatttg
ccgctgaacgtcttactcggcaaaccgcccaaaaccacacgcagcgacaaaaccgtgagg
tcgtctgaaaaaccgtttaacgcgggcaatatcgacatcaccgaagccgcctaccgcgtt
ctgcgcctgcctgccgttgccgccaaaaacttcctgattaccatcggcgaccgcagcatc
ggcggcatgacccaccgcgaccaaatggtcggcaaataccaaacccccgtagccgactgc
gccgttaccatgatgggcttcaacacctatcgcggcgaagcgatgtctatgggtgaaaaa
ccgaccgtcgccctgtttgacgcgcctgcctcgggcagaatgtgcgtcggcgaagccatc
accaacatcgcggcggtcaacatcggcggcatcggcaatatcaagctttccgccaactgg
atggcggcgtgcggcaacgaaggcgaagacgaaaaactctaccgcaccgtcgaagcggtt
tctaaagcctgtcaggcattggatttgagcatccccgtgggcaaagacagcctgtcgatg
aaaaccgtttggcaagacggcgaagagaaaaaatccgtcgtctcgccgttgagcctgatt
atctccgcgttcgcacctgtcaaagacgtgcgcaaaaccgttacgcccgagttgaaaaac
gtcgaagacagcgtattgctgtttatcgatttgggcttcggcaaagcacgcatgggcggc
tcggcgttcggtcaggtgtacaacaatatgagtggcgacgcgcccgatttggacgataca
ggtcgtctgaaagccttttacagcgtgattcaacagcttgtcgccgaagacaaactcttg
gcgtatcacgaccgcagcgacggcggcttgtttgcaacgctggcggaaatggcgtttgcg
gggcgttgcgggttggatatcacattaggaagcatactttttgcaaccatgatagcaacc
tatacacctgcccagattgaccacgacctaagccttgttaatgctggttctatcatctct
accaaagaaaacataatccgttcgctgtttaacgaagagcttggtgcagttttgcaggtt
cgtgcagaagatactgactatgtactcaagcagtttgacaagaaagaattttttgtaaac
aagggtggcttctctccgcgcaagataggaaaatttgccagccattatattggcacaatc
aatccgacatccgaccgtcttgtaatcactgctgctgatgaaactctgttcgaccaaacc
cgcgccgacctgcaacgcgcatggcaggaaaccagccacgccatccaacgcctgcgcgac
aaccccgcctgcgccgacagcgagttcgccctgattggcgacaacgaacgcagcgcattg
tttgccgacgcgaagtttgatgtaaacgaagacatcgccgcgccgttcgtcaacagcggc
gcgaaacccaaaatcgccatcctgcgcgaacagggcgtgaacgggcaaatcgaaatggcc
gccgcgttcacacgcgcaggattcgatgcctacgacgtgcatatgtccgacctgatggca
ggccgcgtccaccttgccgacttcaaaatgctggcggcgtgcggcggcttcagctacggt
gacgtactcggcgcgggcgaaggctgggcgaaatccatcctgttccaccccgccttgcgc
gaccagttcgccgccttcttcgccgacccgaacacgctgacattgggcgtgtgcaacggc
tgccagatggtcagcaacctcgccgaaatcatccccggcacggcaggctggccgaagttc
aaacgcaacctgagcgaacagttcgaagcgcgcctgagcatggttcacgtccccaaatca
gcctccctgatcctgaacgaaatgcaaggctccagcctgcccgtcgtcgtcagccacggc
gaaggccgcgccgacttcgcgcttcacggcggcaaaatttcagacggcctcggcatcgcg
ctgcaatacgtcgacggacaaaaccaagtcacccaaacctacccgctcaaccccaacggc
tcgccgcaaggcatcgccggcgttaccaacgccgacggccgcgttaccatcatgatgccc
caccccgaacgcgtgtaccgcgccgcacaaatgagctggaaaccggaagactggacggaa
ctgtccggctggtaccgcctctttgccggagcaaggaaggctttgggttaa
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