Neisseria meningitidis FAM18 (serogroup C): NMC1749
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Entry
NMC1749 CDS
T00458
Symbol
murF
Name
(GenBank) UDP-MurNAc-pentapeptide synthetase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nmc
Neisseria meningitidis FAM18 (serogroup C)
Pathway
nmc00300
Lysine biosynthesis
nmc00550
Peptidoglycan biosynthesis
nmc01100
Metabolic pathways
nmc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nmc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMC1749 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMC1749 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMC1749 (murF)
Enzymes [BR:
nmc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMC1749 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CAM10923
UniProt:
A1KVL9
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Position
complement(1782892..1784331)
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AA seq
479 aa
AA seq
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MFYHSKTGDKKSAATDVSAARILTKVNMKPLDLNFICQALKLPMPSESKPVSRIVTDSRD
IRAGDVFFALAGGRFDAHDFVEDVLAAGAAAVVVSREDCVAMDGALKVDDTLAALQTLAK
VWRENVNPFVFGITGSVGKTTVKEMLAAVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLN
EKHRYAVIEMGMNHFGELAVLTQIAKPDAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQG
LCSDGMALIPQEDANMAVFKTATLNLNTRTFGIDSGDVHAENIVLKPLSCEFDLVCGDER
AAVVLPVPGRHNVHNAAAAAALSLAAGLSLNDVAEGLKGFSNIKGRLNVKSGIKGATLID
DTYNANPDSMKAAIDVLARMPAPRIFVMGDMGELGEDEAAAMHAEVGAYARDQGIEAAYF
VGDNSVEAAEKFGADGLWFAAKDPLIQVLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
gtgttttaccacagtaaaacaggcgataaaaaatcagccgctaccgatgtgtccgccgcc
cgaatattaacgaaagtaaatatgaaaccactggacctaaatttcatctgccaagccctc
aagcttccgatgccgtctgaaagcaaacccgtgtcgcgcatcgtaaccgacagccgcgac
atccgcgcgggcgatgtgtttttcgcattggcgggcgggcggtttgatgcgcatgatttt
gttgaagacgtattggctgctggtgcggcggcggttgtggtttcgcgcgaagattgcgtt
gcaatggatggcgcgttgaaagtcgatgacacgcttgccgcattgcaaacgttggcaaag
gtgtggcgtgaaaatgtgaatccgtttgtgttcggcattaccggttcggtcggcaagacg
acggtgaaggagatgctggctgcggtattgcgccgccgtttcggcgataatgccgttttg
gcgacggcaggcaacttcaacaaccacatcggattgccgttgactttgttgaaattaaac
gaaaaacaccgctatgccgtgattgaaatgggtatgaaccattttggcgaactggcggtt
ttgacacaaatcgccaaacccgatgccgcattggtcaacaacgccatgcgcgcccatgtc
ggctgcggtttcgacggagtgggcgatattgccaaagcgaaaagcgagatttatcaaggc
ttatgttcagacggcatggcactgattcctcaagaagatgccaatatggctgtcttcaaa
acggcaacgcttaatttgaatacgcgcactttcggcatcgatagcggcgatgtccacgcg
gaaaatatcgtgctgaaaccgttgtcgtgcgaatttgatttggtgtgcggcgacgaacgc
gccgccgtggtgctgcctgttcccggccgccacaatgtccacaacgccgccgctgccgcc
gcgctgtctttggctgcaggtttgagtttgaacgatgtggcggaaggtttgaaaggcttc
agcaatatcaaaggccgtctgaacgtcaaatccggaatcaagggcgcaaccctgattgac
gatacttataatgcgaacccggacagcatgaaagccgcgattgacgtgttggcgcgtatg
cctgcgccgcgtattttcgtaatgggcgatatgggcgaactgggcgaggacgaagccgcc
gctatgcacgccgaagtcggcgcgtatgcccgcgaccaaggcatcgaagcggcttatttt
gtcggcgacaacagcgtcgaagcggcggaaaaatttggcgcggacggtttgtggttcgcc
gccaaagacccgttgattcaagtgttgcgccacgatttgcccgaacgcgccaccgtgttg
gtgaaaggttcgcgctttatgcagatggaagaagtggtcgaggcattggaggataagtga
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