Neisseria meningitidis G2136 (serogroup B): NMBG2136_1888
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Entry
NMBG2136_1888 CDS
T01929
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
nmd
Neisseria meningitidis G2136 (serogroup B)
Pathway
nmd00230
Purine metabolism
nmd01100
Metabolic pathways
nmd01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
nmd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NMBG2136_1888 (purL)
Enzymes [BR:
nmd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NMBG2136_1888 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ADY94542
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Position
2017013..2020975
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AA seq
1320 aa
AA seq
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MSVVLPLRGVTALSDFRVEKLLQKAAALDLPEVKLSSEFWYFVGSEKALDAATVEKLQAL
LAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERSMAVWLEG
ALTDEQKQQWAALLHDRMTESVLPDFQTASKLFHHLESETFSGVDVLGGGKEALVKANTE
MGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSL
FGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYPDAAENQGYRFHEEDTHIIMKVETH
NHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPGLKQPWEQDYGKP
EHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSI
QAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDASLDFNSVQRGNPEIERR
AQEVIDRCWQLGGKNPIISIHDVGAGGLSNAFPELVNDAGRGAVFKLREVPLEEHGLTPL
QIWCNESQERYVLSILEKDLDTFRAICERERCPFAVVGTATDDGHLKVRDDLFANNPVDL
PLNVLLGKPPKTTRTDKTVTPSKKPFHADDIDITEAAYRVLRLPAVAAKNFLITIGDRSV
GGMTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPTVALFDAPASGRMCVGEAI
TNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSM
KTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEDSVLLFIDLGFGKARMGG
SAFGQVYNNMSGDAPDLDDTSRLKAFYNVIQQLVAEDKLLAYHDRSDGGLFAVLVEMAFA
GRCGLDIDLNLLLAQTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEELGAVIQVRK
QDVADIINLFYQQQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTWQETSHQIQ
RLRDNPACADSEFALIGDNGRSALFANLKFDVNEDIAAPFINSGAKPKIAILREQGVNGQ
IEMAAAFTRAGFDAYDVHMSDLMAGRIHLADFKMLAACGGFSYGDVLGAGEGWAKSILFH
PALRDQFAAFFADPDTLTLGVCNGCQMVSNLAEIIPGTAGWPKFKRNLSEQFEARLSMVH
VPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQYVDGQNQVTQTYPL
NPNGSPQGIAGITNADGRVTIMMPHPERVYRAAQMSWKPEGWTELSGWYRLFAGARKALG
NT seq
3963 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtcgttttgcccttgcgcggcgttaccgccctttccgatttccgtgttgaaaaa
ctcttgcaaaaagccgccgcactcgatctgcccgaagtcaaattaagcagcgaattttgg
tatttcgtcggcagcgagaaagcacttgatgccgcgactgtcgaaaaactgcaagccttg
ttggcggcgcaaagcgttgaacaaacgcccaaagcgcgcgagggcttgcatttatttttg
gtcacgccccgtttgggtacgatttcgccttgggcttccaaggcaaccaatatcgcggaa
aactgcggtttggcaggcatcgagcgcatcgagcgcagcatggcggtgtggctggaaggt
gcgcttaccgatgaacagaaacagcaatgggcggctttgctgcacgaccgcatgactgaa
tccgtgctgcccgattttcagacggcatccaaattattccaccatctcgaatccgaaact
ttctccggcgtcgatgttttgggcggcggtaaagaggctttggtcaaagccaataccgaa
atgggtttggcactctccgccgacgaaatcgattatctggttgaaaactatcaggctttg
cagcgcaatccgtccgatgttgaattgatgatgttcgcgcaggcaaacagcgaacactgc
cgccacaaaatcttcaacgccgatttcatcctcaacggcgaaaaacaaccgaaatccctg
ttcggcatgatacgcgacacgcacaacgcgcatcccgaaggtacggtcgtcgcttataaa
gacaattcgtccgtaatcgaaggcgcgaaaatcgagcgtttctatccggatgcggcggaa
aaccaaggctaccgtttccacgaggaagacacgcatatcatcatgaaagtggaaacgcac
aaccacccgaccgccatcgcgccgtttgcgggcgcggcgacgggcgcgggcggcgaaatc
cgcgacgaaggtgcgacgggcaaaggttcgcgtccgaaagcgggcttgaccggctttacc
gtgtccaacctcaacatccccggcctcaaacagccgtgggaacaagattacggcaagccg
gaacatatttcctcgccgctggacattatgattgaaggccccatcggcggcgcggcgttc
aacaacgaattcggccgccccaacctcttgggctacttccgcacctttgaagaaaaattt
gacggtcaggttcgcggctaccacaaaccgattatgattgccggcggtctgggcagcatt
caggcgcagcagacgcataaagacgaaatccccgaaggcgcattgctgattcaactgggc
ggcccgggcatgcttatcggcttgggcggcggcgcggcttcttcgatggataccggcacg
aacgacgcgtctttagacttcaattccgtacaacgcggcaaccccgaaatcgaacgccgc
gcgcaggaagtcatcgaccgctgctggcagctcggcggcaaaaacccgattatctccatc
cacgacgtgggcgcgggcggtttgtccaacgccttccccgaactcgtcaacgatgccgga
cgcggcgcggtattcaagctgcgcgaagtgccgttggaagaacacggtttaacgcctttg
caaatctggtgtaacgaatcgcaagagcgttatgtgttgtcgattttggaaaaagatttg
gacaccttccgcgccatctgcgaacgcgaacgctgcccgtttgccgtggtcggcacggcg
accgacgacggccatttgaaagtgcgcgacgatttgttcgccaacaaccccgtcgatttg
ccgctgaacgtcttgctcggcaaaccgcccaaaaccacgcgtaccgacaaaacggttacg
ccgtccaaaaaaccgtttcacgccgacgatatcgacatcaccgaagccgcctaccgcgtt
ttgcgcctgcctgccgtagccgccaaaaacttcctgattaccatcggcgaccgcagcgtc
ggcggcatgacccaccgcgaccaaatggtcggcaaataccaaacccccgtagccgactgc
gccgttaccatgatgggcttcaatacctatcgcggcgaagcaatgtctatgggcgaaaaa
ccgaccgttgccctgtttgacgcgcctgcttcaggcagaatgtgcgtcggcgaagccatc
accaacatcgcggcggtcaacatcggcgacatcggcaacatcaagctctccgccaactgg
atggcggcgtgcggcaacgagggcgaagacgaaaaactctaccgcaccgtcgaagcggtt
tccaaagcctgtcaggcattggatttgagcattcccgtgggcaaagacagcctgtcgatg
aaaactgtgtggcaggacggcgaagagaaaaaatccgtcgtctcgccattgagcctgatt
atctctgcgttcgcgccggtcaaagacgtgcgcaaaaccgttacgcccgaattgaaaaac
gtcgaagacagcgtattgttatttatcgatttgggcttcggcaaagcgcgtatgggcggc
tctgcattcggtcaggtatacaacaacatgagcggcgacgcgcccgatttggacgataca
agtcgtctgaaagcgttttacaacgtgattcaacagcttgtcgccgaagacaaactcttg
gcataccacgaccgcagcgacggcggtttgtttgccgttttggtagaaatggcgtttgcg
gggcggtgcggcttggatatagatttaaatttattgcttgcacaaacatttattaccaac
cataccgctctgtctcaatcattgcggactgaagaggtaaaagcgttggctgaatggcaa
gaaaccattgcccgcacattatttaatgaagagttgggtgctgttatccaagttagaaaa
caagatgttgccgatattatcaatttattctatcaacaacagctgcatcataatgtcttt
gaaatcggtacgttaactgatgagaacacgttaatcatccgcgacgggcaaacgcacctt
atttctgacaacctaatcaaactgcaacaaacctggcaagaaaccagccatcaaatccaa
cgcctgcgcgacaaccccgcctgcgccgacagcgagttcgcattgattggcgacaacgga
cgcagcgcattgtttgccaacctgaaattcgacgtgaacgaagacatcgccgcgccgttt
atcaacagcggcgcgaaacccaaaatcgccatcctgcgcgaacagggcgtaaacgggcaa
atcgaaatggccgccgcctttacccgcgccggattcgatgcttacgacgtgcatatgtcc
gacctgatggcaggccgcatccacctcgccgacttcaaaatgctggcggcgtgcggcggc
ttcagctacggcgacgtactcggcgcgggcgaaggctgggcgaaatcgattctgttccac
cctgctctgcgcgaccagtttgccgccttcttcgccgacccggacacgctgacattgggc
gtgtgcaacggctgccaaatggtcagcaaccttgccgaaatcatccccggcacggcaggc
tggccgaagttcaaacgcaacctgagcgaacagtttgaagcgcgcctaagcatggttcac
gtccccaaatccgcgtcgctgattctgaacgaaatgcaaggctccagcctgcccgtcgtc
gtcagccacggcgaaggccgcgccgacttcgcacttcacggcggcaacatttctgccgat
ttgggcattgcgctgcaatatgtggacggtcaaaaccaagttacccaaacctatccgctc
aaccccaacggctcgccgcaaggcatcgccggcattaccaacgccgacggccgcgtgacc
atcatgatgccccaccccgaacgcgtgtaccgcgccgcacaaatgagctggaaaccggaa
ggctggacggaactgtccggctggtaccgcctctttgccggcgcacgtaaagccttgggc
taa
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