Neisseria meningitidis MC58 (serogroup B): NMB0416
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Entry
NMB0416 CDS
T00027
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nme
Neisseria meningitidis MC58 (serogroup B)
Pathway
nme00300
Lysine biosynthesis
nme00550
Peptidoglycan biosynthesis
nme01100
Metabolic pathways
nme01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nme00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMB0416 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMB0416 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMB0416 (murF)
Enzymes [BR:
nme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMB0416 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AAF40854
UniProt:
Q9K0Y8
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All DBs
Position
424872..426239
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AA seq
455 aa
AA seq
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MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRAGDVFFALAGERFDAHDFVEDVLAA
GAAAVVVSREDCAAMDGALKVDDTLAALQTLAKAWRENVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDDAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
NAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDGIALIPQEDANMAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGDERAAVVLPVPGRHNVHNAAAAAALALAAG
LSLNDVAEGLKGFSNIKGRLNVKSGIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFV
MGDMGELGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDP
LIQVLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
agcaaacccgtgtcgcgcatcgtaaccgacagccgcgacatccgcgcgggcgatgtgttt
ttcgcattggcgggcgagcggtttgacgcgcatgattttgttgaagacgtattggctgct
ggtgcggcggcggttgtggtttcgcgcgaagattgtgctgcaatggatggcgcgttgaaa
gtcgatgacacgcttgccgcattgcaaacgctggcaaaggcgtggcgtgaaaatgtgaat
ccgtttgtgttcggcattaccggttcgggcggcaagacgacggtgaaggaaatgctggct
gcggtattgcgccgccgtttcggcgatgatgccgtgttggcgacggcaggcaacttcaac
aaccatatcggattgccgctgactttgttgaagttaaacgaaaaacaccgctatgccgtg
attgaaatgggcatgaaccatttcggcgaactggcggttttaacgcaaatcgccaaacca
aatgccgcattggtcaacaacgccatgcgcgcccatgtcggctgcggtttcgacggagtg
ggcgatattgccaaagcgaaaagcgagatttaccaaggtttatgttcagacggcattgca
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgttcacgcggaaaatattgtgctgaaaccg
ttgtcgtgcgaatttgatttggtgtgcggcgatgagcgcgccgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctggctttggctgcgggt
ttgagtttgaacgatgtggcggaaggtttgaaaggcttcagcaatatcaaaggccgtctg
aacgtcaaatccggaatcaagggcgcaaccctgattgacgatacttataatgcgaaccct
gacagcatgaaagctgcgattgacgtgttggcgcgtatgcctgcgccgcgtattttcgtg
atgggcgatatgggcgaactgggcgaactgggcgaggacgaagccgccgctatgcacgcc
gaagtcggcgcgtatgcccgcgaccaaggcatcgaagcggcttattttgtcggcgacaac
agcgtcgaagcggcggaaaaatttggcgcggacggtttgtggttcgccgccaaagacccg
ttgattcaagtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcg
cgctttatgcagatggaagaagtggtcgaggcattggaggataagtga
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