Neisseria meningitidis MC58 (serogroup B): NMB1188
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Entry
NMB1188 CDS
T00027
Symbol
ilvD-2
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
nme
Neisseria meningitidis MC58 (serogroup B)
Pathway
nme00290
Valine, leucine and isoleucine biosynthesis
nme00770
Pantothenate and CoA biosynthesis
nme01100
Metabolic pathways
nme01110
Biosynthesis of secondary metabolites
nme01210
2-Oxocarboxylic acid metabolism
nme01230
Biosynthesis of amino acids
Module
nme_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
nme_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
nme00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NMB1188 (ilvD-2)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
NMB1188 (ilvD-2)
Enzymes [BR:
nme01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
NMB1188 (ilvD-2)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
AAF41572
UniProt:
Q9JS61
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Position
complement(1187359..1189218)
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AA seq
619 aa
AA seq
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MPEYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLV
AREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCIS
NCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNVS
NRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHAGRKELFLEAGR
MIVEITKRYYEQNDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFK
MADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTL
KDAIEQWDVTNPENTRAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYS
QDGGLAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVI
IRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGA
IGLVHEGDTVEIDIPNRSIHLAISDEELAARRAEMEARGSKAWKPKNRDRYVSAALRAYG
AMATSADKGAVRDVAQIER
NT seq
1860 nt
NT seq
+upstream
nt +downstream
nt
atgcctgaataccgctccaaaacctccacccacggccgcaatatggcgggcgcacgtgca
ttgtggcgcgccaccggcgtgatggaaaccgacttcggcaagcccatcatcgccgttgcc
aactccttcacccaattcgtgcccggccatgtccacctgcacaatatgggccagctggtt
gcccgcgaaatcgaaaaagccggcgcaatcgccaaagaattcaacaccatcgccatcgac
gacggcatcgctatgggacacagcggcatgctgtactccctgcccagccgcgatttgatt
gccgactctatcgaatatatggtcaacgcccactgcgccgacgcgctggtgtgcatttcc
aactgcgacaaaatcaccccgggcatgctgattgccgcgatgcgcctgaacatccccacc
atcttcgtctccggcggcccgatggaagcgggcaaggttatcggcgtggcaaacatccag
cccgaacgccgtttggacttgattgacgcgatgattgaatcggcggacgacaatgtcagc
aaccggcaagtcgaggaagtcgaacaaaacgcctgcccgacctgcggctcgtgttcgggt
atgtttacggcaaactcgatgaactgcctgaccgaagcactcggcctttccctgcccggc
aacggttcgtatttggcgacccacgccggccgcaaagaattgttcctcgaagccggccgt
atgattgtcgaaatcaccaaacgctattacgagcaaaacgatgaaaccgtgttaccgcgc
agcattgccaccaaaaaagcgtttgaaaacgctatgacgatggatattgcgatgggcggc
agcaccaataccattttgcacctgttggccgttgccaacgaagccggtgtcgatttcaaa
atggcagacatcgaccgcttaagccgcgtcgtgccctgcatctgcaaaaccgcacccaac
aaccacgactactatatggaagacgtgcatcgcgccggcggtatcttcgccatcctgaaa
gaactggacaaagcgggcaaactgcacaccgacgtgcacaccatccacgcgccgacgctg
aaagacgcgattgaacaatgggacgtgaccaatcccgaaaacacccgtgccatcgaacgc
ttcaaagccgcgccgggcggcgtacgcaccacccaagcgttctcgcaaaaccgtatgtgg
aaaaccctcgacctcgaccgcgaaaaaggctgtatccgcgacgtggcacacgcctactcg
caagacggcggtttggcggtcttgttcggcaacatcgccgagcgcggctgcgtggtaaaa
accgcaggcgtggacgagagcatcctcaaattcaccggccgcgcccgcgtgtttgaaagc
caagaagacgcagtagaaggcattttgggcaaccaaatcgtcgctggcgacatcgtcatc
atccgctacgaaggcccgaaaggcggcccgggcatgcaggaaatgctgtatccgacttcc
tacctgaaatctaaaggcctcggcaaagcctgcgctctcttaaccgacggacgcttctcc
ggcggcacatcaggtttgtccatcggacacgcctcgcccgaagcggcggaaggtggcgcg
atcggtttggtacacgaaggcgataccgtcgaaatcgacatccccaaccgcagcatccac
cttgccatttccgatgaagagcttgccgcacgccgtgccgaaatggaagcgcgcggcagc
aaagcatggaagcctaaaaaccgcgaccgctacgtctccgccgcattaagagcttacggc
gcgatggcgacttccgccgacaaaggcgcggtgcgcgacgtagcgcaaatcgaaagataa
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