Neisseria meningitidis MC58 (serogroup B): NMB1996
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Entry
NMB1996 CDS
T00027
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
nme
Neisseria meningitidis MC58 (serogroup B)
Pathway
nme00230
Purine metabolism
nme01100
Metabolic pathways
nme01110
Biosynthesis of secondary metabolites
Module
nme_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nme00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NMB1996 (purL)
Enzymes [BR:
nme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NMB1996 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AAF42323
UniProt:
Q9JXK5
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All DBs
Position
2102032..2105994
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AA seq
1320 aa
AA seq
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MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFVGSEKALDAATVEKLQAL
LAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWLEG
RLNDEQKQQWAALLHDRMTESVLPDFQTASKLFHHLESETFSGVDVLGGGKEALVKANTE
MGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSL
FGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYPNAAENQGYRFHEEDTHIIMKVETH
NHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQPWEQDYGKP
EHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSI
QAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDASLDFNSVQRGNPEIERR
AQEVIDRCWQLGGKNPIISIHDVGAGGLSNAFPELVNDARRGAVFKLREVPLEEHGLNPL
QIWCNESQERYVLSILEKDLDAFRAICERERCPFAVVGTATDDGHLKVRDDLFANNPVDL
PLNVLLGKLPKTTRTDKTVAPSKKPFHAGDIDITEAAYRVLRLPAVAAKNFLITIGDRSV
GGLTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPTVALFDAPASGRMCVGEAI
TNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSM
KTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEDSVLLFVDLGFGKARMGG
SAFGQVYNNMSGDAPDLDDTGRLKAFYSVIQQLVAENKLLAYHDRSDGGLFAVLVEMAFA
GRCGLDIDLNLLLAQTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEELGAVIQVRK
QDVADIINLFYQQQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTWQETSHQIQ
RLRDNPACADSEFALIGDNERSALFADVKFDVNEDIAAPFINSGAKPKIAILREQGVNGQ
IEMAAAFTRAGFDAYDVHMSDLMAGRIHLADFKMLAACGGFSYGDVLGAGEGWAKSILFH
PALRDQFAAFFADPDTLTLGVCNGCQMVSNLAEIIPGTAGWPKFKRNLSEQFEARLSMVH
VPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQYIDGQNQVTQTYPL
NPNGSPQGIAGVTNADGRITIMMPHPERVYRAAQMSWKPEGWTELSGWYRLFAGARKALG
NT seq
3963 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtcgttttgcccttgcgcggcgttaccgccctttccgatttccgtgttgaaaaa
ctcttgcaaaaagccgccgcactcggtctgcccgaagtcaaattaagcagcgaattttgg
tatttcgtcggcagcgagaaagcacttgatgccgcgactgtcgaaaaactgcaagccttg
ttggcggcgcaaagcgttgaacaaacgccaaaagcgcgcgagggcttgcatttgtttttg
gtcacgccccgtttgggtacgatttcgccgtgggcttccaaggcgaccaatatcgcggaa
aactgcggtttggcaggcatcgaacgcatcgagcgcggtatggcggtgtggctggaaggt
cgtctgaacgatgaacagaaacagcaatgggcggctttgctgcacgaccgcatgaccgaa
agcgtgctgcccgattttcagacggcctccaaattattccaccatctcgaatccgaaact
ttctccggcgtcgatgttttgggcggcggtaaagaagctttggtcaaagccaataccgaa
atgggcttggcactttccgccgacgaaatcgattatctggtcgaaaactatcaggctttg
cagcgcaatccgtccgatgttgaattgatgatgttcgcgcaggcaaacagcgaacactgc
cgccacaaaatcttcaacgccgatttcatcctcaacggcgaaaagcagcccaaatccctc
ttcggtatgatacgcgacacacacaacgcgcatcccgaaggcacggtcgttgcctataaa
gacaattcgtccgtaatcgaaggcgcgaaaatcgagcgtttctatccgaatgcggcggaa
aaccaaggctaccgtttccacgaggaagacacgcatatcatcatgaaagtggaaacgcac
aaccacccgaccgccatcgcgccgtttgcgggtgcggcgacgggcgcgggcggcgaaatc
cgcgacgaaggcgcgacgggcaaaggttcgcgtccgaaagcgggcctgaccggctttacc
gtgtccaacctcaatattcccgacctcaaacagccgtgggaacaagactacggcaagccg
gaacatatttcctcgccgctggacatcatgattgaaggcccgatcggcggcgcggcgttc
aacaacgaattcggccgccccaacctcttgggctacttccgcacttttgaagaaaaattt
gacggtcaggttcgcggctatcacaaaccgattatgattgccggcggcttgggcagcatt
caggcgcagcagacgcataaagacgaaatccccgaaggcgcattgctgatccaactgggc
ggcccgggtatgcttatcggcttgggcggcggcgcggcttcttcgatggataccggcaca
aacgacgcgtctttggacttcaactccgtgcaacgcggcaaccccgaaatcgaacgccgc
gcgcaggaagtcatcgaccgctgctggcagctcggcggcaaaaacccgattatctccatc
cacgacgtaggcgcgggcggcctgtccaacgccttccccgaactggtcaacgatgccaga
cgcggcgcagtattcaagctgcgcgaagtgccgcttgaagaacacggcctcaacccgctg
caaatctggtgcaacgaatcgcaagagcgttatgtgttgtcgattttggaaaaagatttg
gatgctttccgcgccatctgcgaacgcgaacgctgcccgtttgccgtagtcggcacggcg
actgacgacggtcatttgaaagtacgcgacgatttgttcgccaacaatcccgtcgatttg
ccgttgaacgtcttgctcggcaaactgcccaaaaccacgcgcaccgacaaaacggttgca
ccgtccaaaaaaccgtttcacgcgggcgatatcgacattaccgaagccgcctaccgcgtt
ttgcgcctgcctgccgtagccgccaaaaacttcctgattaccatcggcgaccgcagcgtc
ggcggtttgacgcaccgcgaccaaatggtcggcaaatatcaaactccagtagccgactgc
gccgttaccatgatgggcttcaacacctatcgcggtgaagcgatgtctatgggcgaaaaa
ccgaccgtcgccctgtttgatgcgcctgcttcgggcagaatgtgcgtcggcgaagccatc
accaacatcgcggcggtcaacatcggagacatcggcaacatcaaactctccgccaactgg
atggcggcgtgcggcaacgaaggcgaagacgaaaaactctaccgcactgtcgaagccgtt
tccaaagcctgtcaggcattggatttgagcatccccgtgggcaaagacagcctgtcgatg
aaaaccgtttggcaggacggcgaggagaaaaaatccgtggtttcaccgttgagcctgatt
atctcagcgttcgcgcctgtgaaagacgtacgcaagactgttacgcctgagttgaaaaac
gtcgaagacagcgtattgttgtttgtcgatttgggcttcggcaaagcgcgtatgggcggt
tcggcgtttggtcaggtgtacaacaatatgagcggcgacgcgcccgatttggacgataca
ggtcgtctgaaagccttttacagtgtgattcagcagcttgttgccgaaaacaaactcttg
gcgtatcacgaccgcagcgacggcggcttgtttgccgttttggtagaaatggcgtttgcg
gggcggtgcggcttggatatagatttaaatttattgcttgcacaaacatttattaccaac
cataccgctctgtctcaatcattgcggactgaagaggtaaaagcgttggctgaatggcaa
gaaaccattgcccgcacattatttaatgaagagttgggtgctgttatccaagttagaaaa
caagatgttgccgatattatcaatttattctatcaacaacagctgcatcataatgtcttt
gaaatcggtacgttaactgatgagaacacgttaatcatccgcgacgggcaaacgcacctt
atttctgacaacctaatcaaactgcaacaaacctggcaagaaaccagccatcaaatccaa
cgcctgcgcgacaaccctgcctgcgccgacagcgagttcgcactgattggcgacaacgaa
cgcagcgcattgtttgccgacgtgaagttcgacgtgaacgaagacatcgccgcgccgttt
atcaacagcggcgcgaaacccaaaatcgccatcctgcgcgaacagggcgtaaacgggcaa
atcgaaatggccgccgcctttacccgcgccggattcgatgcttacgacgtgcatatgtcc
gacctgatggcaggccgcatccacctcgccgacttcaaaatgctggcggcgtgcggcggc
ttcagctacggcgacgtactcggcgcgggcgaaggctgggcgaaatcgattctgttccac
cctgctctgcgcgaccagtttgccgccttcttcgccgacccggacacgctgacattgggc
gtgtgcaacggctgccaaatggtcagcaaccttgccgaaatcatccccggcacggcaggc
tggccgaagttcaaacgcaacctgagcgaacagtttgaagcacgcctgagcatggttcac
gttccgaaatcagcgtcgctgattctgaacgaaatgcaaggctccagcctgcctgtcgtg
gtcagccacggcgaaggccgcgccgacttcgcgcttcacggcggcaatatttccgccgat
ttgggcattgcgctgcaatacatcgacggacaaaaccaagtgacccaaacttatccgctc
aaccccaacggctcgcctcaaggcatcgccggcgttactaacgccgacggccgcatcacc
atcatgatgccccaccccgaacgcgtgtaccgtgccgcgcaaatgagctggaaaccggaa
ggctggacggaactgtccggctggtaccgcctctttgccggcgcacgtaaagccttgggc
taa
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