Numida meleagris (helmeted guineafowl): 110389421
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Entry
110389421 CDS
T06015
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
nmel
Numida meleagris (helmeted guineafowl)
Pathway
nmel00520
Amino sugar and nucleotide sugar metabolism
nmel00541
Biosynthesis of various nucleotide sugars
nmel01100
Metabolic pathways
nmel01250
Biosynthesis of nucleotide sugars
Module
nmel_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
nmel00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
110389421 (GNE)
00541 Biosynthesis of various nucleotide sugars
110389421 (GNE)
Enzymes [BR:
nmel01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
110389421 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
110389421 (GNE)
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Gene cluster
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
DRTGG
FGGY_N
Glucokinase
Motif
Other DBs
NCBI-GeneID:
110389421
NCBI-ProteinID:
XP_021235468
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Position
Z:complement(51590653..51627751)
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AA seq
767 aa
AA seq
DB search
MDCKWKLEISFTIDSLGWISDSPNMTIMQNELYFKNLSKQKQKEDMEKNGNNHKLRVCVA
TCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTI
VRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEG
GEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNK
DYMSVIRVWLGEDVKPKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVD
AGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPV
INLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLK
SIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYT
QLNPKTYEDRLDLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEW
SSVDLRTPVSDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHE
LIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLVVEGMS
MKNEEVVSAAHLIQAAKLGNTKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHY
VNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY
NT seq
2304 nt
NT seq
+upstream
nt +downstream
nt
atggattgcaagtggaaactagaaatatcttttaccattgacagcttgggatggatttct
gatagtcctaacatgactattatgcaaaatgaactgtatttcaagaatctttcaaaacag
aaacagaaagaagacatggagaagaatggaaacaaccacaaacttcgtgtttgtgttgct
acttgcaaccgtgctgattattcaaaattagctcccattatgtttggtattaaggcagaa
ccacagttctttgagcttgatgtcgtagtgcttggttcccacttgattgatgattatggg
aacacttatcgcatgatcgaacaagatgacttcgatattcatacaagattgcacactatt
gtgagaggggaggatgaggcagccatggtggaatcagtgggcctcgcattagtgaagtta
ccagatgtcctgaaccgcctgaaacctgacataatgatagttcatggtgacagatttgat
gctttggcactagccacatctgcagccctgatgaatattcgcattcttcacattgaaggt
ggggaagtcagtgggaccattgacgactctattagacatgccataaccaaactggcccat
taccacgtgtgctgcacaaggagtgcagagcagcatttgatagccatgtgtgaagaccac
gatcgcatccttttagcaggctgtccttcatatgacaagcttctctctgccaaaaataag
gactacatgagtgttatacgcgtgtggctgggtgaagatgttaaacccaaagattatata
gttgctctgcaacatcctgtaaccacggatattaaacattccataaagatgttcgaactg
acactagatgcactcatttcatttaacaagagaacgcttgttctattccccaatgtagat
gcaggaagcaaagagatggttcgggtgatgaggaagaagggcattgaacatcatcccaat
tttcgggcagtgaagcatgtcccatttgaccagttcattcagctagttgcccatgctggt
tgtatgattggtaacagcagttgtggtgtcagagaagtgggagcatttggcacacctgtc
atcaacttggggacacgtcagacaggaagagaaacaggtgaaaatgttcttcatgttcgt
gacgctgacacacaggataaaattctgcatgcgctacagctccagtttggtaagcagtat
ccatgctcaaaaatatatggtgatggtaatgctgttccaaggattttgaagttccttaaa
tctattgacctcaaagagccattgcaaaagaaattctgttttcctcctgtcaaagataat
atttctcaagatatagaccatattctagagactcagagtgctttggctgtggacctaggc
ggaacaaatctccgagtagcaattgtcagtatgaagggtgaaatagttaagaagtatacc
cagctcaaccctaaaacttacgaagacagactagatttaattctaaagatgtgtgtagaa
gctgcatcggaggcagtaaatctgaactgcagaattttgggagtaggtatttccacaggt
ggacgggtaaaccctcgagaaggaattgtacttcactccacaaaactcattcaggagtgg
agctctgtagatctcagaaccccagtatctgatgctctacacttgccagtctgggtggac
aatgatggaaactgtgctgctctggcagaaaggaaatttggtcatggaaaaggaatagaa
aattttgtaacactcatcactggtacaggaattggaggtggaatcattcatcaacatgaa
ttgatccacggcagttctttctgtgctgctgagcttgggcatattgtagtgtctttagat
ggaccagagtgcctgtgtggtagccaaggatgtatagaagcatatgcctctggaatagca
ttacagagagaagctaagaaactgcatgacgaggatctacttgtagtggaaggaatgtca
atgaagaatgaggaggttgttagtgctgcacatctcattcaagcagctaaacttggaaac
acaaaggcagaaagcattctcagaacagctggtacagcattaggacttggagttgtgaac
attctgcacaccatgaacccctctcttgtgatcctctctggagtcctagccagccactat
gttaatgctgttaaagatgtgatacatcgacaggctttgtcgtctgttaaaactgtggat
gtggtggtctcaaatctagcagaccctgctcttcttggagctgctagcctggtactagat
tatactacccgtagaatatactag
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