KEGG   Numida meleagris (helmeted guineafowl): 110393351
Entry
110393351         CDS       T06015                                 
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
nmel  Numida meleagris (helmeted guineafowl)
Pathway
nmel04270  Vascular smooth muscle contraction
nmel04350  TGF-beta signaling pathway
nmel04510  Focal adhesion
nmel04520  Adherens junction
nmel04530  Tight junction
nmel04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:nmel00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    110393351 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110393351 (ROCK1)
   04520 Adherens junction
    110393351 (ROCK1)
   04530 Tight junction
    110393351 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110393351 (ROCK1)
 09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    110393351 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nmel01001]
    110393351 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:nmel03036]
    110393351 (ROCK1)
Enzymes [BR:nmel01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     110393351 (ROCK1)
Protein kinases [BR:nmel01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   110393351 (ROCK1)
Chromosome and associated proteins [BR:nmel03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    110393351 (ROCK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C APH PH_11
Other DBs
NCBI-GeneID: 110393351
NCBI-ProteinID: XP_021241789
LinkDB
Position
2:complement(100800394..100883696)
AA seq 1358 aa
MSTGESFESRFEKIDGTLKDPKSEVNVDCLLDGLDALVYDLDFPALRKNKNIDNFLNRYK
DTVNKMRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSSRRVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNEISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKDDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLDEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLSVSAENSNDNRTGS
SMDKSVMENMQKMIYDLEEQLHNEMQLKDEMEQKCRSSNITLDKIMKELDEEGNQRKNLE
LTVSQIEKEKMALQHKINDYQRKIEQESEKRRNVENEVSTLKDQMEDLKKISQHSQITNE
KITQLQKQLEEANDLLRTESETAVRLRKGNTEMSKSLSQVESLNRELQERCRVLESAKLQ
VEKDYYQLQAALESERRDRSHGSEMIGELQVRITTLQEELKNLKNNLERVEAERKQAQDR
LNHSEKEKNNLEIDLNYKLKSLQDRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEK
KVKEERAAREKAENRIVQAEKQCSMLDFDLKQSQQKLEHLLQQKERLEDEVKNLSHQLEQ
ETNKRIMAQNELKAQAFEADNLKGSEKQLKQEINTLLEAKRLLEVELAQLAKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIDEKNKETQRKMQDLQNEKETLTTQLDLAETK
AESEQLARALLEEQYFELSQESKKAASRHRQEMTDKDSIIRRLEETNNTLTKDVDLITKE
NSEISEKIKKQEEEYKLKKEEEINNIRMQYEKSISTERTLKTQAVNKLAEIMNRKDFKID
RKKASTQDLRKKEKENRKLQLELNQEKEKFNQMVVKYQKELNEMQAQLAEESTYRNELQM
QLDSKESDIEQLRRKILDLQQGMDSTSVSSLQPDEIDGNLSESRLEGWLSIPNKGNIKRH
GWKKQYVVVSSKKILFYNDEKDKDQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIF
QILYANEGECRKDVEVEPVQPTEKTNFLSHKGHEFIPTIYHFPANCEACAKPLWHVFKPP
AALECRRCHVKCHRDHLDKKEELIAPCKVSYDVTSARDMLLLASCQDEQKKWVNHLVKKI
PKNPPAAFVRASPRTVSTRSSANQSFRKVVKNTSGKTS
NT seq 4077 nt   +upstreamnt  +downstreamnt
atgtcgacgggagaaagttttgagtctcgatttgaaaaaatcgacgggactttaaaggat
cccaaatccgaagtgaacgtggactgtttgctggatggattagatgctttggtatatgac
ttggattttcctgccttacgaaaaaacaaaaacattgataacttcttaaacaggtataaa
gacacagtaaataaaatgagagatctgcgcatgaaagctgaagattatgaagtggtgaag
gtgattggcagaggggcatttggggaggttcagttggtaaggcataaatcgtcaagaaga
gtgtatgctatgaaacttctgagcaaatttgagatgataaaaagatcagattctgcgttc
ttctgggaagaaagggatattatggcttttgctaatagtccctgggttgttcagttattt
tacgcattccaagatgatcgttacctttacatggtcatggagtacatgcctggtggagac
cttgtgaatttaatgagtaactacgacgttcctgagaaatgggcaagattttatactgct
gaagttgttcttgcattagatgcaattcactcaatgggctttatacacagagatgtgaag
cctgataatatgctgctagataaagctggtcatttaaaactagcagattttggtacttgt
atgaagatgaacaaggaaggtatggtacgatgcgatacagctgtaggaacaccagactat
atctcccctgaagtgttgaaatcccagggtggtgacggttactatggacgagaatgtgac
tggtggtcagttggagtctttttgtatgagatgcttgtaggtgacacacctttttatgca
gattctttggttggaacatacagtaagattatgaaccacaagaactcccttaccttccct
gatgacaacgagatctctaaagaggcaaaaaaccttatttgtgcctttttaactgatagg
gaagtgagactaggacgaaatggtgtagaagaaattaaacgccatcttttcttcaaagat
gatcagtgggcttgggagactctcagagacactgtagcaccagttgtgcctgacttaagt
agtgacatagacactagtaattttgatgatctggatgaagacaaaggagaggaggaaaca
tttcccattccaaaagcatttgtgggcaaccagcttccttttgttggatttacgtattac
agcaaccgtcggtatttatctgtctctgcagaaaattccaatgataacagaacaggctcc
agtatggataaaagtgtgatggaaaatatgcagaagatgatctatgatttggaagagcag
ctacataatgaaatgcagttgaaagatgaaatggagcagaagtgcagatcttcaaacata
acgctagacaagataatgaaagaactggatgaggagggaaatcaaagaaagaacctagaa
ttaacagtgtcccagattgagaaggaaaagatggcactgcagcataagataaatgactac
caaagaaaaattgaacaagagagtgaaaagagacggaacgtggaaaacgaagtgtctacg
ctaaaagatcaaatggaagacttgaaaaaaatcagccagcattcacaaattacaaatgag
aagataacacagttacaaaaacaactagaagaagccaatgatttgctacggacagaatcg
gaaacagcagtaagactgagaaagggtaacacggaaatgagcaagtcattaagtcaagta
gaatcactgaatagagaactgcaggaaaggtgcagagttctagaaagcgcaaaactgcag
gtggagaaagattattatcaactgcaagcagctttggaatcagaacgaagggacagaagt
catggatctgaaatgattggagaactacaggttcggattacgactttacaagaagaatta
aaaaaccttaaaaataatcttgaaagagtggaagcagaaagaaaacaagcacaggatagg
cttaatcattcagaaaaggaaaagaataacttggagatagatttgaactacaaactcaag
tctttgcaagaccgcttagaacaggaagtaaatgaacacaaagtgaccaaagctcgatta
actgacaaacatcagtcaatagaggaggcaaaatcagttgcaatgtgtgaaatggaaaaa
aaagtgaaggaagaaagggcagcaagagaaaaggcagagaatcgaatagtgcaggctgaa
aaacagtgttccatgctagacttcgacctgaagcaatctcagcagaaactggaacacctt
cttcagcaaaaggaaagactggaagatgaagtaaagaatctgtcacatcagctagagcaa
gagacaaataagcgaataatggcgcagaatgaattaaaggcgcaagcttttgaagcagat
aacttgaagggttctgagaagcaactgaaacaagaaatcaacacgttattggaagcaaag
agattactggaagttgagttggctcaacttgctaaacagtacagaggaaatgaaggtcaa
atgcgtgagcttcaggatcagcttgaagcggagcagtatttttcgacactttacaaaact
caggttaaggaactgaaggaagaaattgatgaaaagaataaagaaactcaaagaaaaatg
caggacttgcaaaatgagaaagaaacactcactacgcagctggatttagctgaaaccaaa
gctgagtcggaacagttggcacgagcacttcttgaagagcagtattttgaattgagtcag
gagagcaaaaaggcagcatcaagacataggcaagaaatgactgataaggacagcatcata
agaaggctggaggaaactaacaacaccttaaccaaagatgtcgatttaataacaaaagaa
aattcagaaatcagtgaaaaaattaagaaacaggaggaagaatataaactgaaaaaagag
gaagaaatcaacaatattagaatgcagtatgagaagagtatcagcactgagagaactctg
aagacacaggctgtcaacaaactggctgagataatgaatagaaaagattttaaaatagat
agaaagaaagcaagtacgcaagatttgaggaagaaagagaaggaaaaccgaaagctacaa
ttagagcttaatcaagaaaaagagaaattcaatcagatggtagtgaaataccaaaaggag
cttaatgaaatgcaagcgcaactagcagaagaatcaacatacaggaatgagctacagatg
cagctggatagtaaagagagtgacatagaacaactacgaaggaaaattctggatctccag
caaggaatggattccaccagtgtttctagtctacagccagacgaaattgatggaaatctt
tcagaatcaaggcttgaaggttggctttcaataccaaacaagggaaacataaagcggcat
ggctggaagaaacagtacgttgtggtgagcagtaaaaagatactgttctataatgatgaa
aaggacaaggaccagtctaatccatccatggtactagacatagataagctgttccatgtc
cgacccgtaactcaaggagatgtatatagagcagaaactgaagaaattcctaaaatattc
cagattctgtatgctaatgagggggaatgcaggaaggatgtggaggtagaaccagtacag
cctacagagaagacaaactttctaagtcataaaggccatgaatttattccaacaatatac
cactttccagccaactgtgaggcctgtgccaaacctctttggcacgtctttaaaccccct
gctgccctggaatgtcgaagatgccacgtgaagtgccatagggaccacttggacaaaaag
gaggagttaattgcaccgtgcaaagtgagttacgatgtaacttcagcaagagatatgttg
ttactggcatcctgtcaagatgaacagaagaagtgggtgaatcatttagtaaagaagatc
cctaagaacccaccagctgcttttgttcgtgcttctcctagaactgtgtctacaagatcc
tcagcgaaccagtcattccgaaaagttgttaaaaatacttctggaaaaacgagctaa

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