Numida meleagris (helmeted guineafowl): 110406041 Help Entry 110406041         CDS       T06015                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism nmel  Numida meleagris (helmeted guineafowl) Pathway nmel04115   p53 signaling pathway nmel04140   Autophagy - animal nmel04150   mTOR signaling pathway nmel04218   Cellular senescence nmel04910   Insulin signaling pathway nmel05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:nmel00001]  09130 Environmental Information Processing   09132 Signal transduction    04150 mTOR signaling pathway     110406041 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     110406041 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     110406041 (TSC2)    04218 Cellular senescence     110406041 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110406041 (TSC2)  09160 Human Diseases   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     110406041 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:nmel01009]     110406041 (TSC2) Protein phosphatases and associated proteins [BR:nmel01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      110406041 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  110406041 NCBI-ProteinID:  XP_021267713 LinkDB All DBs Position 13:6536603..6567196 Genome browser AA seq 1833 aa AA seqDB search MAKPQSKDSGLKEKFKNLLGLGTSRGSSKSSEGKQTEFIITAEILKELSIECGLSNRIRA ISQICEVAKTKKIEEHAVEAIWKVVADMLQPERPAEARHAVLHLLKSIIQGQGERLGILR AHFFKVIKDYPSNEDLHERLEVFKALTENGRYITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLEDYVADMVHKICILCIQTSSSVDIEISLQVLDAVVCYNCLPSENLPVFI ITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMADAALLRGAVFFVG MALWGAHRLNSLKNSPTSVLPSFLKAMTCPNAVVSYEIVLSITRLIKKYGKELQAVTWDI LLDIMERLLQQLQSLESQELKSIVHDLLTTVEELCDQNEFHGSEERFFELVERCADQRPE SSVLNLIAYRAQSIHPAKDGWIHNLQMLMERFFRNESRSAVRIKVLDVLSFVLSINRQFY EEELINLVVISQLAHIPEDKDHQVRKLATQLLVDLAEGCNTHHFNSLLDIIEKVAVHSLS SPSELEERDLLSYSASLEDVKTAVLGLLIILQTKLYSLPSSHAMRVYEMLIHHIQRHYLY AYSLAVASSIRLQVFDFLLMLRADSLHRLGLANKDGAVRFSPYCLCDFVEAEKRASEKKP TGTLSPPSGSPSVPSQNSAIRIGHLPYSMVFGVLLQCLKQETDWKVLKLVLNKLPESLRY KVLFLTSPCNIDLLASALSYMLTDKKTTDRLHGTPEGFSRTDLHLAVVPVLTALISYHNY LDKAKQREIVYCLEHGLIYRCANQCVVALSVCSVEMPDIIIKALPVLIVKLTHISATANM AIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIR CRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSSLRLAKNAKQGLN NSPPVKELKEPSAVDAFRSRSISVSEHVVRSRIQTSITSSSLGSADENSMAQADDNLKNL HLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTITTSVGTGTR SLLGLDSGELQSSTESGSDPVLQVRQTKEAPAKLESQAGQQVCRSSRNRVRSMSGGHALR VGALDGSASHFPGGSASQGTQSPPAPASRPEKTNPAPQTPLQKEKANLAAYVPLLTQGWA EILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRETALYKSLSV PSSSLATGTAKPSLLQRSNTVASFSSMYQSSCQGKLHRSISWAESAVVLEEGSPLEMELK ETESPAESPESEDFETSCSEQVLSEERFAKAQESYSRSSSTSSQEEKSLKSDELVEGGIP IGRALPVEDGRALEELSFQPSQPLSKSSSSPELQTLQEILKDANGREVTRRLSTEVKSKS QSGNLEGEGLGSWLSKGEDTRAAGTGGLDGSGPATSPRSPSGHRPRGYTISDSAPSRRGK RMERDAFKSRTAATNAEKVPGINPSFVFLQLYHSPFFGDENNKPLLLPNETFEKSVQLLD QIPSYDTHKIAVLYVGEGQSNNEIAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKIYLG GLDVCGEDGQFTYCWHDDIMQAIFHIATLMPTKDLDKYRCDKKRHLGNDFVSIVYNDSGE DFKLGTIKGQFNFVHVIITPLDYDCNLVTLQCRKDMEGLVDTSVAKIISDKNLPFVARQM ALHANMASQVHHSRSNPTDTYPSKWIARLRHIKRLRHRLREETQYQTPGLPLQMHPTAPT KPSPQMAQDPPPAYETGQRKRLISSVDDFTEFV NT seq 5502 nt NT seq  +upstreamnt  +downstreamnt atggcaaagcctcaaagcaaggattctgggctgaaggagaagttcaagaatctcttgggg ctgggaacgtcccggggaagttcaaagtcatcagagggcaagcaaacggaattcatcatc actgcagaaatactcaaggaactgagcatagaatgtggattaagtaataggatacgagca atcagccaaatctgtgaagtggcaaaaacaaaaaaaattgaagagcacgcagtggaagca atatggaaggtggtagctgatatgctccagccagagcgcccagctgaagccagacatgct gttcttcatctcctaaagtcaatcattcaaggacagggtgagagattaggaatccttaga gcacatttttttaaggttattaaggactatccctccaatgaagacttgcatgaacggctt gaagtgtttaaggctctaacagagaatggacgatacatcacttacttagaagaagagtta gctgactttgtgctacagtggatggatgttggtttgtcttcagaattccttttggtttta gtgaacctggtgaaattcaacagttgctatctggaagactatgtagctgacatggtccac aagatatgcatcttgtgtattcagacttcatcatctgtggacatagagatttctttgcaa gttttagatgctgttgtttgctataactgtctgccatcagagaacctgccagtatttatc atcactttgtgccgtaccatcaacgtgaaggaactctgtgagccatgctggaagcttatg cgcaaccttttgggaactcatttgggacacagtgcaatctacaacatgtgcaggatcatg gaagacagagcttacatggccgatgcagcgctgctgagaggagcggtgttctttgttggg atggctctctggggtgctcatcgcctcaattcactcaagaattccccaacttcagtgctg ccttcattcctcaaggccatgacatgtcccaatgcagttgtatcttacgagatagttctg tccatcacccgtctgataaagaagtatgggaaggaactgcaagctgtaacctgggatatc ctcttggacatcatggagcgattactgcagcagctgcagagtttagagagccaagaactt aagtccattgtacatgatcttttgactacagtagaagagctctgtgaccagaatgagttt catggttctgaagagaggttttttgagctggtggaaagatgtgctgatcagagaccggaa tcttctgtattaaacttgatagcatacagagctcaatccattcatcctgccaaagatggc tggattcacaacctgcagatgttaatggagagattcttcagaaacgaaagtcgtagtgct gttcgtattaaagttctggatgtcttgtcctttgtactgagcattaacagacagttctat gaggaagagctgataaacttggttgtaatctctcagctggctcacattccagaggataaa gaccatcaagttcgaaaattggccactcagctacttgtagaccttgctgaaggctgcaac acacatcactttaacagcttgcttgatatcatagaaaaggtggctgtgcattctctctca tctccttctgaactggaagagagggatttgctatcatattcagcttctttggaggacgtg aagacagcagttcttggacttctgataattcttcagacaaaactctacagcttaccttcc agccatgccatgcgggtgtacgagatgctgattcaccacatccagcgccactatctgtat gcgtacagccttgctgtggctagcagcatcagattgcaggtatttgatttcctcctgatg cttcgagctgactccctccaccgtcttggccttgctaacaaggatggagcagtgagattc agcccttactgtctgtgtgattttgtagaagcagagaagagagcttctgagaaaaagcct actggtacgctctctccgccttcaggaagtcccagtgtgccttcccagaacagcgccatt cggatcggacatttgccatactcaatggtctttggagtccttctgcagtgtttgaagcaa gagacagactggaaggtgttgaagttggtcctcaacaaactaccagaatccctccgctat aaagtgttgtttttaacctctccttgtaacatagacctcctggcatctgcactgagctac atgctcacagacaagaagacaacggacagactccatggtaccccagaaggcttttcccgc actgacttgcatctggctgtagttccagtactgacagcattgatatcttatcataattat ctggacaaagctaaacagcgtgaaatagtgtattgcctggaacacggtcttatttatcgc tgtgcaaaccagtgcgttgtagcactctctgtctgcagtgttgagatgcccgacatcatc ataaaggcacttcctgtcttaatagtcaaattaacccacatatctgctacggccaatatg gcaatccctctcttagaatttctttcaactctggcaaggctgcctcacctctacaggaac tttgctgcagagcagtatgccagcgtgtttgccatctccctgccatacacaaacccttcc aagtttaaccagtacattgtttgcctggcccaccatgtgatagctatgtggttcattcgg tgtcgccttcccttccgaaaggattttgttccctttattaccaagggtttgcgctccaac gtgctgctctcctttgatgacacacctgaaaaggacagtttcagggctcgtagtacaagc ctcaatgagaggccaaaaagtagtttaagactagccaaaaatgcaaagcaaggcttgaat aactctcctccagtgaaagagctgaaagaaccctctgcagttgatgccttccgatcccgc agcatcagtgtgtctgaacatgtggtccgcagtcggatacagacatccatcactagttcc agcttgggctctgcggatgaaaattcaatggctcaggctgatgacaacttaaaaaatctc catctggaactcactgagacttgtctggatatgatggcccgatacgtcttctccaacttc accgcggtgcctaagaggtctcctgtgggtgagtttctgttggctggaggaaggacaaag acatggctggttggcaacaagctggtgaccatcactacaagtgtcggaacagggacaagg tccttgcttggcctagactctggagagctccaaagcagcacagaatcaggctcagacccc gttttgcaagtgagacaaactaaagaagctccagcaaaacttgaatctcaagctgggcag caggtttgcagaagctctcgcaacagagtcagatccatgtctggtggtcacgccttacgt gttggtgccttagatggctcagcctctcacttccctggtggctcggcttcccaaggcacg cagagtcctcctgctcctgcatctcggccagagaagactaatcctgctccacagacgcct ttgcagaaagaaaaagcgaacttagctgcgtatgtcccactgctgacacagggctgggca gaaatcctcgtgcgcagacccacaggcaacacgagctggctaatgagcctggagaaccca ctcagtcccttttcttcagacattaacaatatgcccctgcaagagctgtccaacgcactc atggctgcggagcgttttaaagagcaccgagagacagctctctacaagtccctctctgtt ccttcctccagcttggccactgggacagccaagccatcgcttctccagcgttccaacaca gtggcctctttctcttccatgtaccagtccagttgtcaagggaagttgcacaggagcata tcctgggcagaatctgcggtagtgctggaggaagggagccccttggaaatggagctgaag gaaaccgagtccccagctgagtctccggagagtgaagattttgagacgtcgtgttctgag caagtcctgagcgaggaaaggttcgctaaagcccaggagtcttacagcaggtcctcctcg acctctagccaggaagaaaaatctctgaagtcggacgagctggtggagggtggtattccc atcgggagagcgctgcccgtggaggatggccgggcactggaggagctctccttccagccc tcccagccgctcagcaagtcgagctcttcccccgagctgcagacactgcaggagatcctc aaagatgcaaacggcagagaagtaacaaggaggctgagcacggaagtgaaatccaaatct cagtctgggaacctggaaggggaaggactgggcagttggctgagcaagggtgaggacacc agagcagcgggcacgggggggttggatggcagcggccccgccacctcgccacgctcccca tctgggcaccggccccgggggtacaccatctccgactctgccccatcacggagagggaag aggatggagagagatgccttcaagagcagaacggcagccaccaatgctgagaaagtacct ggaataaacccaagctttgtgtttttacaattgtaccattccccgttctttggtgatgaa aacaacaagcccctcctgttgccaaatgagacgtttgaaaaatcggtgcagctcctggat cagattccttcatatgacacacacaagatcgccgtgctctacgttggagagggccagagc aacaatgaaatcgctattctgtcaaatgagcacggctcctatcgctataccgagttcctg acgggcttagggaagctcattgaactcaaagactgccagccagataaaatctacctcggt ggcctggatgtatgtggggaggatggacagttcacctactgctggcacgatgacatcatg caagccattttccacattgctacactgatgcccacgaaggatttggataaatatcgctgc gacaagaagaggcaccttgggaatgattttgtttctattgtttacaatgattctggtgag gacttcaaactgggaacaataaagggtcagttcaatttcgtgcatgttatcataacaccg cttgactatgactgcaacctggtcacgctgcagtgtcgaaaagacatggagggccttgta gacacgagtgttgctaagatcatctctgacaagaacctaccgttcgtcgcccgtcagatg gccctgcatgctaacatggcttcccaggttcaccatagtcgatccaaccctactgacacc tacccatccaaatggatcgctcggctgcggcacatcaagcggctgaggcaccggctacgt gaagaaacccagtaccaaactcctggccttcccctgcagatgcacccaactgctccgacc aagccctctccgcagatggctcaggacccaccgccagcctacgagaccgggcagaggaag cggctcatctcctcggtggatgacttcactgagttcgtgtag

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