Nonlabens marinus: NMS_1445
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Entry
NMS_1445 CDS
T09770
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nmf
Nonlabens marinus
Pathway
nmf00300
Lysine biosynthesis
nmf00550
Peptidoglycan biosynthesis
nmf01100
Metabolic pathways
nmf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nmf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMS_1445
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMS_1445
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMS_1445
Enzymes [BR:
nmf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMS_1445
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAO55454
UniProt:
W8VQ50
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Position
complement(1525885..1527132)
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AA seq
415 aa
AA seq
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MNIESLYSSFKSSKGVHTDTRTLQPGQLYVALSGENFDGNAYVDAAFAKGASHVVCSDPG
KASQENVTVVADTLKALQELATYHRNKLNLPIVGLTGSNGKTTTKELIIAVLSQKFQVKG
TKGNLNNHIGVPLTLLSFDEQTQIGVVEMGANHIGEIAELCQIAQPNFGLITNFGKAHLE
GFGSLEGVKRGKSELYDYLRANNGKAIVLSTDVEQLARSKDLERRVTPIMDLKSSQPIEF
TFENETITTQLTGSYNFNNMELAAGVGLEFGLHAAEIGKGLSSYKPVNNRSQLIVRDSYT
VIMDAYNANPTSMKAALENLALQDGFTVAILGDMFEMGSYAAPEHQEIVNHAEKLKINQV
ILLGHHFFETQSATVQKFKTFEDFLQNPPISSDLKATVLIKGSRGMALERVLEIL
NT seq
1248 nt
NT seq
+upstream
nt +downstream
nt
atgaatatagaatcattatacagttcgttcaaatccagtaaaggcgttcataccgatacc
cgaaccttacagcctgggcagctatacgttgccttgtcgggtgaaaattttgatggtaat
gcctatgtagatgccgctttcgcgaaaggtgcttcacatgtagtctgcagcgacccgggt
aaagcatctcaagaaaacgtaaccgtagttgcagatactctaaaagcattacaggagtta
gccacataccatagaaataaattaaacctacctattgtaggtttaacaggaagtaatggt
aaaacgaccaccaaagaattaatcatcgccgttctttcacaaaagtttcaagtcaaaggc
actaaaggaaatttaaataatcatataggtgtcccacttaccttattatcctttgatgag
caaacacaaataggtgtggtggaaatgggtgcgaatcacataggtgaaattgctgaatta
tgccagatcgcccaacctaactttgggttgattactaatttcggaaaagcgcatttagaa
ggtttcggcagtctggaaggtgttaaaagaggcaaaagcgaactctacgattatttaaga
gcaaataacggcaaagctatagtgctttccaccgatgttgagcagctagccagatcaaaa
gacctagaaaggcgtgtgacacccattatggatttgaaatcctctcaacctatcgaattc
acttttgaaaacgaaacaatcaccacccaacttaccggtagttataattttaacaatatg
gaattggcagcaggagttggtcttgagtttgggctacatgctgcagagatagggaaaggt
cttagtagctataagcctgtcaacaataggtcgcaattgatagtaagagatagttacacc
gtgataatggatgcatataatgcaaatcctaccagcatgaaagcggctttggaaaacctt
gcgttacaagatggttttacggtagccattctaggtgatatgtttgaaatggggtcttat
gctgccccagaacatcaagaaattgtcaatcatgcagaaaaactaaagatcaatcaggtt
attttactaggacatcatttttttgaaacgcaaagcgcaacggtacaaaaattcaagact
tttgaagactttttacagaaccctcctatttccagcgacttaaaagctactgttttgata
aaaggctctcgcggcatggctttggaacgcgtgttagaaattttgtag
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