Neisseria meningitidis alpha14 (cnl strain): NMO_0973
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Entry
NMO_0973 CDS
T00954
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nmi
Neisseria meningitidis alpha14 (cnl strain)
Pathway
nmi00290
Valine, leucine and isoleucine biosynthesis
nmi00620
Pyruvate metabolism
nmi01100
Metabolic pathways
nmi01110
Biosynthesis of secondary metabolites
nmi01210
2-Oxocarboxylic acid metabolism
nmi01230
Biosynthesis of amino acids
Module
nmi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NMO_0973 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NMO_0973 (leuA)
Enzymes [BR:
nmi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NMO_0973 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
P22_Cro
Motif
Other DBs
NCBI-ProteinID:
CBA05812
UniProt:
C6S6Y5
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All DBs
Position
1003637..1005430
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AA seq
597 aa
AA seq
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MQLDIDRLVAYFGGVNALAEALKQHDPENAATTAAIYKWRTRGSLPLAQLQKLTALAEAQ
GRPLDLNAFLQKNESLERTEMTQANRVIIFDTTLRDGEQSPGAAMTKEEKIRVARQLEKL
GVDIIEAGFAAASPGDFEAVNAIAKTITKSTVCSLSRAIERDIRQAGEAVAPAPKKRIHT
FIATSPIHMEYKLKMKPKQVIEAAVKAVKIAREYTDDVEFSCEDALRSEIDFLAEICGAV
IEAGATTINIPDTVGYSIPYKTEEFFRELIAKTPNGGKVVWSAHCHNDLGLAVANSLAAL
KGGARQVECTVNGLGERAGNASVEEIVMALKVRHDLFGLETGIDTTQIVPSSKLVSTITG
YPVQPNKAIVGANAFSHESGIHQDGVLKHRETYEIMSAESVGWATNRLSLGKLSGRNAFK
TKLADLGIELESEEALNAAFARFKELADKKREIFDEDLHALVSDEMGSMNAESYKFISQK
ISTETGEEPRADIVFSIKGEEKRASATGSGPVDAIFKAIESVAQSGAALQIYSVNAVTQG
TESQGETSVRLARGNRVVNGQGADTDVLVATAKAYLSALSKLEFSAAKPKAQGSGTI
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgcaattagatatagaccgcttggttgcttatttcggcggcgtgaacgcgcttgccgaa
gcgttgaaacagcacgatcccgaaaatgccgcgacgaccgccgccatctataaatggcgc
acgcgcggctcgctgcctctggcgcaactgcaaaagctgaccgcgttggcggaagcgcaa
ggcaggccgctggatttgaatgcttttttacaaaaaaacgaatctctggagagaacagaa
atgacacaggccaaccgcgttatcattttcgacaccaccctgcgcgacggcgagcagtcg
cccggcgccgctatgaccaaagaggaaaaaatccgcgtcgcccgccagctggaaaaattg
ggtgtggacatcatcgaagcgggttttgccgctgccagcccgggcgatttcgaggcggtc
aatgcgattgcgaaaaccattaccaaatcaacggtctgttcattgtcccgcgccatcgag
cgggacatccgtcaggcgggtgaggccgttgcgcccgcgccgaaaaaacgcatccacacc
ttcatcgccaccagccccatccatatggagtacaaattgaagatgaagccgaagcaggtg
attgaggcggcggtcaaagcggtgaaaatcgctcgtgaatacaccgacgatgtggaattt
tcctgcgaagacgcgttgcgttcggaaatcgatttccttgccgaaatctgcggcgcggtg
attgaagcgggcgcgaccaccatcaatattcccgataccgtcggctattcaatcccgtac
aaaaccgaagaatttttccgcgaactgattgccaaaacgcccaacggcggcaaagtcgtt
tggtcggcacactgccacaacgatttgggcttggcggttgccaattcgcttgccgcatta
aaaggcggcgcgcgtcaggtggaatgtactgtcaacggcttgggcgaacgtgcaggcaat
gcttcggttgaagaaatcgtgatggcgttgaaagtgcgccacgacttgttcggcttggaa
accggcatcgataccacgcaaatcgtgccttcgtccaaactggtgtccaccattacgggc
tatcccgtgcagcccaataaagccattgtcggtgccaatgccttttcgcatgaatcgggc
atccatcaggatggggtgctgaaacaccgcgaaacttacgagattatgtccgccgaatcg
gtcggctgggcaacaaaccgtttgagcttgggcaaattgtccggccgcaacgccttcaaa
accaagctggcggatttgggcatcgagttggaaagcgaagaggcactgaacgccgcgttt
gcccgcttcaaagaactcgccgacaaaaaacgcgaaatcttcgatgaagacctgcacgca
ctggtatccgacgaaatgggcagcatgaatgccgagagctacaaattcatctcccaaaaa
atcagcaccgaaaccggcgaagagccgcgcgccgacatcgtgttcagcatcaaaggcgaa
gaaaaacgcgcttccgccacaggctccggccccgtggatgcgattttcaaagcgattgaa
agcgtggcgcaaagcggcgcggctttgcagatttattccgtcaacgccgtcacgcaaggt
acggaaagccagggcgaaaccagcgtccgtctggcgcgcggcaaccgcgtcgtcaacggt
cagggcgcggataccgacgttttggttgccactgccaaagcctacctttccgctttgagc
aagctggaatttagtgccgccaaaccgaaagcgcagggcagcggtacgatttga
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